Results 81 to 90 of about 1,265,417 (348)

Transcriptional regulation of neuropeptide receptors underlies context‐dependent adaptation in Drosophila melanogaster

FEBS Open Bio, EarlyView.
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu, Yanan Wei, Zekun Wu, Tianmu Zhang, DoHoon Lee, Hadi Najafi, Woo Jae Kim   +6 more
wiley   +1 more source

Electrical pulse stimulation reflecting the episodic nature of real‐life exercise modulates metabolic and secretory profile of primary human myotubes

FEBS Open Bio, EarlyView.
Here, we introduced an intermittent electrical stimulation protocol mimicking the episodic nature of real‐life exercise in vitro by alternating low‐ and high‐frequency stimulation. In comparison with widely used continuous stimulation, it enhanced the rate of glucose and fatty acid oxidation, but not the myokine release.
Klára Gabrišová, Tímea Kurdiová, Daria Barkova, Natália Pálešová, Jana Babulicová, Silvia Tyčiaková, Marta Novotová, Mária Balážová, Miroslav Sabo, Václav Pustka, Jozef Ukropec, Barbara Ukropcová   +11 more
wiley   +1 more source

Bundle Branch Reentrant Ventricular Tachycardia [PDF]

, 2005
Bundle branch reentrant (BBR) tachycardia is an uncommon form of ventricular tachycardia (VT) incorporating both bundle branches into the reentry circuit.
Kusniec, Jairo, Mazur, Alexander, Strasberg, Boris   +2 more
core   +2 more sources

Ventricular arrhythmias in young competitive athletes: Prevalence, determinants, and underlying substrate [PDF]

, 2018
Whether ventricular arrhythmias (VAs) represent a feature of the adaptive changes of the athlete's heart remains elusive. We aimed to assess the prevalence, determinants, and underlying substrates of VAs in young competitive athletes.Background--Whether ...
Badano, Luigi Paolo, Bellu, Roberto, Berton, Giampaolo, Cipriani, Alberto, Corrado, Domenico, D'Ascenzi, Flavio, De Lazzari, Manuel, Iliceto, Sabino, Mastella, Giulio, Muraru, Denisa, Niero, Alice, Palermo, Chiara, Perazzolo Marra, Martina, Peruzza, Francesco, Portolan, Leonardo, Schiavon, Maurizio, Sciacca, Federco, Tollot, Saverio, Trovato, Domenico, Zorzi, Alessandro   +19 more
core   +2 more sources

Dual Chamber Pacemaker Implant in Coronary Sinus Leading to Several Complications

Diagnostics
Permanent pacemaker implantation is a low-risk procedure. However, complications may occur at a rate of around 4–8%. We present a case where initial implantation resulted in complications that could have been avoided by meticulous assessment of lead ...
Nancy Wassef, Mina Ibrahim, Christine Botrous, Amr Anos, Kai Hogrefe, Janaka Pathiraja   +5 more
doaj   +1 more source

Association of temporary complete AV block and junctional ectopic tachycardia after surgery for congenital heart disease

Annals of Pediatric Cardiology, 2015
Aim: Junctional ectopic tachycardia (JET) is a postoperative complication with a mortality rate of up to 14% after surgery for congenital heart disease. This study evaluated the risk factors of JET and explored the association of postoperative temporary ...
Christian Paech, Ingo Dähnert, Martin Kostelka, Meinhardt Mende, Roman Gebauer   +4 more
doaj   +1 more source

Berberine–cinnamic acid co‐crystal effect in ameliorating hyperlipidemia might be regulated through the PI3K/AKT/mTOR/SREBP‐1 signaling pathway

FEBS Open Bio, EarlyView.
Berberine–cinnamic acid co‐crystal (BBR‐CA) inhibits the phosphorylation of the phosphatidylinositol 3‐kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) pathway, suppressing the transfer of pre‐sterol regulatory element‐binding proteins‐1 (SREBP‐1) from the endoplasmic reticulum to the nucleus. This results in a decrease in the expression level of
Wenheng Gao, Yunlong Li, Lihua Chen, Wenshuo Yang, Yong He, Ye Yang, Dengke Yin, Song Tan   +7 more
wiley   +1 more source

Bloqueio Aurículo-Ventricular Completo Congénito. Caso Clínico e Revisão da Literatura [PDF]

, 2015
Introduction: Congenital complete atrioventricular block (AVB) without cardiac malformation is a rare and potentially fatal condition. In most cases it is associated with maternal systemic lupus erythematosus through transplacental passage of antibodies ...
Borges, A, Freitas, I, Massa, AC, Serrano, F   +3 more
core  

The impact of Hnrnpl deficiency on transcriptional patterns of developing muscle cells

FEBS Open Bio, EarlyView.
We performed nanopore whole‐transcriptome sequencing comparing RNA from Hnrnpl‐knockdown versus control C2C12 myoblasts to investigate the contributions of Hnrnpl to muscle development. Our results indicate that Hnrnpl regulates the expression of genes involved with Notch signaling and skeletal muscle, particularly splicing patterns of specific muscle ...
Hannah R. Littel, Mekala Gunasekaran, Audrey L. Daugherty, Natalya M. Wells, Johnnie Turner, Christine C. Bruels, Christina A. Pacak, Isabelle Draper, Peter B. Kang   +8 more
wiley   +1 more source

Ventricular response during lungeing exercise in horses with lone atrial fibrillation [PDF]

, 2013
Reasons for performing the study Atrial fibrillation (AF) is the most important dysrhythmia affecting performance in horses and has been associated with incoordination, collapse and sudden death.
De Clercq, Dominique, Decloedt, Annelies, Sys, Stanislas, Van Der Vekens, Nicky, van Loon, Gunther, Verheyen, Tinne   +5 more
core   +2 more sources