Giant cell myocarditis masquerading as orbital myositis with a rapid, fulminant course necessitating mechanical support and heart transplantation. [PDF]
Giant cell myocarditis (GCM), a rapidly progressive inflammation of the myocardium, is associated with fulminant heart failure, refractory ventricular arrhythmias, and conduction system abnormalities.
Aksoy, Olcay+5 more
core +1 more source
Premature MicroRNA-1 Expression Causes Hypoplasia of the Cardiac Ventricular Conduction System. [PDF]
Mammalian cardiac Purkinje fibers (PFs) are specified from ventricular trabecular myocardium during mid-gestation and undergo limited proliferation before assuming their final form.
Evangelista, Melissa+5 more
core +2 more sources
Dbh+ catecholaminergic cardiomyocytes contribute to the structure and function of the cardiac conduction system in murine heart [PDF]
The heterogeneity of functional cardiomyocytes arises during heart development, which is essential to the complex and highly coordinated cardiac physiological function.
An, Yanru+27 more
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745-4 Sudden “Arrhythmic” Death in Young People with Apparently Normal Heart [PDF]
The aim of the present study was to assess whether and how often the ultimate diagnosis of structural heart disease underlying sudden cardiac arrest depends on histologic examination of the myocardium and specialized conduction system. Among 186 cases of
Angelini, Annalisa+3 more
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High resolution 3-Dimensional imaging of the human cardiac conduction system from microanatomy to mathematical modeling [PDF]
Cardiac arrhythmias and conduction disturbances are accompanied by structural remodelling of the specialised cardiomyocytes known collectively as the cardiac conduction system.
A Atkinson+49 more
core +1 more source
Real-time optical manipulation of cardiac conduction in intact hearts [PDF]
Optogenetics has provided new insights in cardiovascular research, leading to new methods for cardiac pacing, resynchronization therapy and cardioversion.
Bocchi, L.+16 more
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The cardiac sodium channel displays differential distribution in the conduction system and transmural heterogeneity in the murine ventricular myocardium [PDF]
Cardiac sodium channels are responsible for conduction in the normal and diseased heart. We aimed to investigate regional and transmural distribution of sodium channel expression and function in the myocardium.
A. A. M. Wilde+12 more
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Impact of functional studies on exome sequence variant interpretation in early-onset cardiac conduction system diseases [PDF]
Aims The genetic cause of cardiac conduction system disease (CCSD) has not been fully elucidated. Whole-exome sequencing (WES) can detect various genetic variants; however, the identification of pathogenic variants remains a challenge.
Asano, Yoshihiro+44 more
core +1 more source
Anatomic-electrophysiological correlations concerning the pathways for atrioventricular conduction. [PDF]
The remarkable success of radiofrequency ablation in recent decades in curing atrioventricular nodal reentrant tachycardias has intensified efforts to provide a solid theoretical basis for understanding the mechanisms of atrioventricular transmission ...
Anderson, RH, Ho, SY, Mazgalev, TN
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Electrocardiographic patch devices and contemporary wireless cardiac monitoring. [PDF]
Cardiac electrophysiologic derangements often coexist with disorders of the circulatory system. Capturing and diagnosing arrhythmias and conduction system disease may lead to a change in diagnosis, clinical management and patient outcomes.
Carlson, SK+9 more
core +2 more sources