Results 21 to 30 of about 93,944 (304)

Purkinje Cardiomyocytes of the Adult Ventricular Conduction System Are Highly Diploid but Not Uniquely Regenerative

Journal of Cardiovascular Development and Disease, 2023
Adult hearts are characterized by inefficient regeneration after injury, thus, the features that support or prevent cardiomyocyte (CM) proliferation are important to clarify.
Hirofumi Watanabe, Ge Tao, Peiheng Gan, Baylee C. Westbury, Kristie D. Cox, Kelsey Tjen, Ruolan Song, Glenn I. Fishman, Takako Makita, Henry M. Sucov   +9 more
doaj   +1 more source

Neonatal Deletion of Hand1 and Hand2 within Murine Cardiac Conduction System Reveals a Novel Role for HAND2 in Rhythm Homeostasis

Journal of Cardiovascular Development and Disease, 2022
The cardiac conduction system, a network of specialized cells, is required for the functioning of the heart. The basic helix loop helix factors Hand1 and Hand2 are required for cardiac morphogenesis and have been implicated in cardiac conduction system ...
Rajani M. George, Shuai Guo, Beth A. Firulli, Michael Rubart, Anthony B. Firulli   +4 more
doaj   +1 more source

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders [PDF]

, 2013
Elevated resting heart rate is associated with greater risk of cardiovascular disease and mortality. In a 2-stage meta-analysis of genome-wide association studies in up to 181,171 individuals, we identified 14 new loci associated with heart rate and ...
Kooner, A.S., Cusi, D., Munroe, P., Laiho, Päivi, P. Elliott, D. Absher, Assimes, Themistocles L., Ingelsson, E., C. Wijmenga, Sibon, O.C., Sanna, Serena, Rossin EJ, Pfeufer, Arne, Anneli Pouta, van der Schouw, Y.T., Qi, L., Knowles, JW, Hicks, Andrew A, D. J. Hunter, Groop L, van der Klauw, MM (Melanie), Nelis, M, Albert, Christine M., Olsen, J.V., Sibon, Ody C M, Mari Nelis, Chip Stewart, Toshiko Tanaka, Kim, Young Jin, Peters, Annette, van Gilst, W., Whitfield, J., A. U. Jackson, Kim, Y. J., Poulter, Neil R, Smith, AV, Holewijn, S, Steven A McCarroll, Arnar, D.O., Kathryn A Miller, McArdle WL, Scott RA, D. O. Arnar, Navarro, Pau, M. R. Markus, Antti Jula, Qi, Lu, Qi L, Uitterlinden, André G, Tarasov, K., Forouhi, Nita G., O'Donnell, C., W. L. Caulfield, Jarvelin, M., Stefansson, K, Chambers, John C, Whitfield, JB, Smith AV, O'Donnell, CJ, M. den Heijer, Waite L, Gary Curhan, Robert A Scott, K. L. Lunetta, Montgomery, G.W., Igl, W., Draisma HH, Sever, Peter S, Knowles, J., Tarasov, KV, Quertermous, T., Heckbert, Susan R., J. C. Bis N. Bouatia Naji, Hsueh, Wen-Chi, Milani, L., Hingorani A, Munroe, PB, de Geus, E.J., de Bakker, Paul I. W., M. Chung, Handsaker, Robert E, Qi, L, Thompson, J., de Geus, Eco J C, Eijgelsheim, Mark, Smith, GD, Evans DM, Handsaker, Robert E., S. H. Wild, Claude Bouchard, Strachan, David P., Ong, KK, Smith, G., Dan E Arking, Johnson, T, Jordan T Shin, M. Kumari, Jula A, Shuldiner AR, Femke Hoogstra-Berends, Jarvelin MR, Xie, W.J., Alonso, Alvaro, Kerr, KF, R. N. Luben, Peter S Chines, et al., Joshua W Knowles, van Gilst, WH, Quertermous T, Peal, D.S., Ketkar S, Rizzi F, Olsen, Jesper V., Nieminen MS, de Boer, Rudolf A., Loic Yengo, Johnson T, Y. T. van der Schouw, Zhang, W., P. Navarro, Raitakari, Olli T., Vitart, Veronique, van der Schouw, Y., Westra, HJ, Iribarren, Carlos, Ody C M Sibon, Laiho, Paeivi, Martin, Nicholas G, A. Johansson, Jolanda M A Boer, Kähönen, M., C. Langenberg, Ketkar, S, Iacoviello, Licia, Neil R Poulter, van der Schouw, YT, Hadley, D., Evelin Mihailov, Montasser ME, E. J. de Geus, Thompson, JR, Pourcain, Beate St., Westra, H., B. St Pourcain, Ong, K.K., Gudbjartsson, Daniel, Weedon, Michael N., Wareham, N.J., N. C. Onland Moret, Scott, Robert A., Barlassina C, Ulf Gyllensten, van der Schouw YT, Visscher, P., Pourcain, BS, Loos R.J., E. B. Rimm, Erdmann, Jeanette, Tardif JC, Salo, P, Alonso A, van Veldhuisen DJ, B. A. Oostra, E. Widen, Pedersen, Nancy L., Tim D Spector, Verschuren, W. M. Monique, van Gilst, Wiek H, Zhang, WH, Laiho, P, Willer, Cristen, Pedersen, Nancy L, Visscher, PM, Brage, S., Hicks, Andrew A., Lynch SN, Cornelis MC, Verschuren, W.M.M., Rankinen, T, Jackson, A.U., Sever, P.S., Annette Peters, Wilson, James F, Huikuri, Heikki V, den Hoed, M, Kemp, J.P., Rankinen T, Iacoviello, L, S. Bandinelli, Hofman A, Federica Rizzi, Mateo Leach I, de Geus, EJC, Daniel Gudbjartsson, Erdmann, J, Leusink M, Hottenga, J.J., Peter M Visscher, Albert V Smith, Hicks, A.A., Beckmann, Jacques S, Weedon MN, Alvaro Alonso, H. J. Westra, Polasek, Ozren, Brage, S, Thorsteinsdottir, U, Ruth J F Loos, Jarvelin, MR, Elliott P, Miller, Kathryn A., van Duijn, Cornelia M., W. C. Hsueh, Sehmi, J.S., Müller-Nurasyid, M., Lakatta, Edward G., Shields DC, Medland, S.E., Virtamo J, Jackson, Anne U, Newton-Cheh, C, Snieder, Harold, A. S. Havulinna, Huikuri HV, Elizabeth J Rossin, Tuomilehto J, Zhao, JH, D. Kuh, Kivimaki, M., Tardif, J.C., Yang, L., Pramstaller, PP, O'Reilly PF, Mihailov E, Tarasov, Kirill V, Smith, A., Vollenweider, P, Wilmar Igl, Knowles JW, Tarasov, K.V., Marcello R P Markus, Brundel, Bianca J J M, Stolk, Ronald P, Singleton AB, Nolte, I., Visscher, Peter M., Rao DC, Elisabeth Widen, Elliott, P., Fuchsberger, C., M. Dörr, L. Qi, Pramstaller, P., Cornelis, Marilyn C, Salo, P., Zhao, J., Rankinen, Tuomo, Kim, YJ, Tanaka, T, Marjo-Riitta Jarvelin, Handsaker, R.E., Lakatta, E., Jamshidi, Yalda, Psaty, Bruce M., Lynch, S.N., Wong, QN, Khaw, K., Jan A Kors, Kiemeney, L.A.L.M., Mihailov, Evelin, Mitchell, Braxton D., T. Rankinen, Tuomilehto, J., Sarah E Medland, N. J. Timpson, U. Thorsteinsdottir, Morrison, Alanna C, Pedro Marques-Vidal, Milan, David J, Kim, Y., Dirk J van Veldhuisen, Serena Sanna, Lakatta, EG, Holm H, P. A. Lind, E. Ingelsson, Caulfield, W., Shin, Jordan T., CHARGE AF Consortium, den Hoed M, M. E. Montasser, Anne B Newman, Richard A Kronmal, Timpson NJ, Markus, M., Hartikainen, A., Dorret I Boomsma, Segrè AV, Bochud, M., W. Wheeler, Wheeler, W., Wong, Q., Kari Stefansson, Bis JC, Khaw, KT, Hartikainen, AL, Rimm, Eric B, Peal DS, Hu, Frank B., Jensen, MK, Rotter JI, Mihailov, E., Chines, Peter S., Pedersen, N., St Pourcain, Beate, Poulter, N.R., Smith, G.D., Fischer, K (Kirsten), Absher D, Vilmundur Gudnason, Rao, Dabeeru C., Thompson, J.R., Jensen, M., Medland, Sarah E., Felix, Stephan B, Bis, J.C., Wilson, J.F., Samani, N.J., Kronmal, Richard A, Gerjan Navis, T. Johnson, Raitakari, O., Pedersen, NL, van Duijn CM, D. Gudbjartsson, Samani NJ, Olli T Raitakari, Soranzo, N., E. Mihailov, Waeber, G., Zoltán Kutalik, Pouta, A., Widen, Elisabeth, Wong, Q.N., Stacey N Lynch, Montasser, ME, Raitakari, OT, Shin JT, Feitosa MF, Isaacs, A., Hunter DJ, S. Padmanabhan, Segrè, A.V., Kiemeney, L.A., St. Pourcain, B., Hwang, S.J., Global BPgen Consortium, Wilson, James F; id_orcid, O'Reilly, P.F., Gabrielle Boucher, Kooner JS, Montasser, M., Navarro P, Lokki, M.L.L., Kuh, D, Young Jin Kim, Ring, S., J. Virtamo, Jerome I Rotter, Brundel, B.J., Morrison AC, Lakatta, Edward G, de Geus, E.J.C., Willemsen, G.; id_orcid, A. Alonso, Rimm, E., Chambers, J.C., Khaw, Kay-Tee, Sever, P., Navarro, P., Montgomery, Grant W, Stricker BH, Ring, SM, Hayward C, Forouhi NG, Holm, H, van der Schouw, Yvonne T., Hoed, M. den, Samani, Nilesh J, Gudbjartsson, D, Kristiansson, Kati, P. M. Visscher, Boomsma, Dorret I., J. S. Sehmi, McArdle, W.L., Sever, PS, A. G. Uitterlinden, Hsueh, W.C., Handsaker, R., Fischer K, Ladenvall C, Michael N Weedon, Hayward, Caroline, Lynch, SN, Lehtimäki T, Kerr, K., Erdmann J, Albert Hofman, Salo P, Igl, Wilmar, Yang, Jiaqi, Scott, R., Boucher, G, T. Esko, Arnar, DO, CARDIoGRAM Consortium, Lynch, S., Handsaker, RE, Scott, RA, Lindsay Waite, Hicks, A., van Veldhuisen, D.J., Müller-Nurasyid, Martina, Rimm, EB, David M Evans, Albanes D, Boucher G, Arnar, D., Kooner, JS, J. A. Kors, Kiemeney, Lambertus A, K. Fischer, Hicks AA, Hicks, AA, Franke, L., Junttila J, Lakatta, E.G., Cusi, D, Weedon, MN, Stanton, A.V., Oostra, B.A., M. M. van der Klauw, A. C. Morrison, Patrick T Ellinor, L. Groop, Pourcain, B. St, Jamshidi Y, Harmen H M Draisma, Yang J, Sibon, Ody C. M.; id_orcid, Graaf, J. de, Michael Boehnke, Westra, H.J., Spector, T.D., Loos, R.J.F., Forouhi, N., G. W. Montgomery, Lynch, Stacey N, Dina, Christian, Wilson, JF, Forouhi, NG, Waeber, G, Jesper V Olsen, Waite, Lindsay, Bouchard, C, de Geus, Eco J. C., Holm, H., Kim, Y.J., Wilson, J., I. B. Borecki, Dawood Darbar, Absher, D., Sehmi, Jaban S., A. B. Newman, Sandosh Padmanabhan, Leif Groop, Weedon, M., Shields, DC, Froguel, P., K. A. Miller, Braxton D Mitchell, Smith GD, David S Peal, Timpson, N.J., Ulf Ekelund, de Bakker, P., Kooner AS, Shields, D., A. Isaacs, Froguel, P, Lynch, Stacey N., Hoogstra-Berends, F., V. Gudnason, Harris, Tamara B, Mark Walker, Boer, J.M.A., Robert E Handsaker, Claes Ladenvall, Boehnke, M, Groop, L, Sanna, S, Isomaa, B., Walker M, de Bakker, P.I.W., Nolte IM, de Geus EJ, Kemp, John P, Newman, Anne B, Raitakari OT, Paul I W de Bakker, Hu, F.B., Hottenga, J.-J., Ellinor, Patrick T., Langenberg, C, Borecki, Ingrid B., Evans, D., M. N. Weedon, Bochud, Murielle, Marques-Vidal, P, Huikuri, HV, Leusink, Maarten, Albert, C.M., Lind, Lars, Sehmi, Jaban S, A. L. Hartikainen, Stefan Kääb, Hoogstra-Berends, Femke, Lunetta, Kathryn L., Milan, David J., Navarro, P, Peal, David S, Evans, DM, Heckbert, Susan R, Tamara B Harris, Ronald P Stolk, Eriksson, Johan, J. Junttila, F. B. Hu FB, Kanon, B, Chanock, Stephen J, Gérard Waeber, Huikuri, H., Wong, A., Wen-Chi Hsueh, Yengo, L., Isomaa, B, Lundby, A., Chines, P.S., Zhang, W.H., Medland SE, John D Rioux, Vandenput, Liesbeth, D. J. van Veldhuisen, I. Rudan, Melanie M van der Klauw, Jarvelin, M.R., Jensen MK, Draisma, H., Stolk, RP (Ronald), Havulinna, A.S., Nolte, IM (Ilja), Martin, NG, J. P. Kemp, S. N. Lynch, Johnson, T., van Duijn, C., Salomaa, V, Jian Yang, Yang, Jian, J. R. O'Connell, Y. Liu, Kanon B, Martin, N., J. T. Shin, Shuldiner, A.R., Padmanabhan S, Jaspal S Kooner, Liu Y, Sharp, S., Sharp S, Hsueh WC, C. M. Albert, Nicola Glorioso, Ring, Susan M, Marja-Liisa L Lokki, Milan, D.J., Isomaa, Bo, Caulfield, W.L., O'Donnell CJ, Snieder, H, Peter S Sever, Nieminen, Markku S, B. Kanon, M. J. Go, Hunter, David J, Päivi Laiho, W. Igl, Hsueh, W.-C., Chines, Peter S, Ellinor, Patrick T, Esko, T, Rotter, Jerome I, Nicholas J Wareham, Claudia Langenberg, Ekelund, U., Whitfield, John B, Kuh, D., Montasser, M.E., Kors, Jan A, Stewart C, Spector, T., Benaglio, Paola, Thompson, John R., Kerr, Kathleen F., Lundby A, Visscher PM, de Boer, R.A., P. Zitting, Erdmann, J., M. Nelis, Rioux, John D, P. I. de Bakker, Laiho P, A. A. Hicks, Bouchard, C., Paavo Zitting, Absher, Devin, Forouhi, Nita G, Dina C, van der Harst, Pim, S. M. Ring, Luigi Ferrucci, Leach, IM, Zitting P, de Boer, RA, Alicia Lundby, Olsen, J., Mika Kähönen, de Boer, R., Fuchsberger, Christian, Peal, D., Njajou, Omer T., Mihailov, E, Pim van der Harst, Heckbert SR, D. C. Rao, Beckmann, J.S., Bruce M Psaty, Olsen, JV, Lokki, Marja-Liisa L, Chambers, John C., Jula, A, Nita G Forouhi, Jamshidi, Y., Strachan, D., Ekelund, U, Waeber, Gerard, Polasek, O., A. Hofman, Ong, Ken K., Uitterlinden, A., Scott, R.A., Chanock, S., Kooner, Angrad S, Sinisalo, Juha, A. S. Kooner, Fischer, Krista, Harris, TB, Søren Brage, Jacqueline de Graaf, Lind, L, Harris, T., Wareham, Nicholas J., O'Connell, J.R., Chanock, SJ, QT-IGCGC Consortium, Arking, Dan E., Lokki, Marja-Liisa L., J. Eriksson, Marcel den Hoed, Draisma, H.H., Draisma, Harmen H. M., Kemp, J., Go, Min Jin, Kääb, Stefan, Timpson, Nicholas J., Zhao, J.H., Singleton, A.B., Ekelund U, Yongmei Liu, S. Ketkar, K. Kristiansson, Maarten Leusink, Miller KA, Verschuren, W., Vitart, V, Bouatia-Naji, N, Rossin, E.J., N. Glorioso, Fuchsberger C, M. Lorentzon, Evans, David M., Hayward, C, Pramstaller PP, Kemp, JP, Assimes, Themistocles L, Jensen, M.K., van der Harst P, Strachan, DP, Whitfield, J.B., Luben, Robert N., Assimes, TL, Themistocles L Assimes, Assimes, T., Spector, TD, CHARGE-AF Consortium, Igor Rudan, J. C. Tardif, Kumari M, W. L. McArdle, Darbar D, Kronmal RA, Lunetta KL, Nieminen, M.S., Ferrucci, L., Glorioso, N., Hartikainen, A.L., Jouke-Jan Hottenga, Holewijn S, Kronmal, RA, Esko T, Leach, I.M., Müller Nurasyid M, Shin, J., Strachan, David P, R. A. de Boer, Kronmal, R., Lakatta EG, Stanton, Alice V., Samani, Nilesh J., Cisca Wijmenga, Bouatia-Naji, Nabila, Virtamo, J, PR GWGWAS Consortium, Hofman, Bert, Hartikainen AL, Langenberg, Claudia, Markus, M.R.P., Hwang SJ, Olsen JV, Brundel, Bianca J. J. M., Marques-Vidal, Pedro, van Veldhuisen, Dirk J., Widen E, Ferrucci, Luigi, Sibon, O.C.M., W M Monique Verschuren, Jaban S Sehmi, Kirill V Tarasov, Feitosa, Mary F., Markus, M.R., Spector, Tim D., Jorma Viikari, Witteman JC, Snieder, H., Yengo L, Havulinna AS, Fuchsberger, C, S. A. McCarroll, Kay-Tee Khaw, Uitterlinden, André, S. E. Medland, Pouta, Anneli, Medland, Sarah E, Kraft, P, Rizzi, F., Lorentzon, Mattias, Pouta A, Sharp, Stephen, Khaw, K.-T., Sanna S, Stolk, Ronald P., Iribarren, C, Chambers, J., Almgren P, Marques Vidal P, Johansson, A, Chanock SJ, J. Yang, O'Donnell, Christopher J., Willemsen G, Mark Eijgelsheim, Havulinna, Aki S, K. K. Ong, Patricia B Munroe, Goyette, P, Chambers, JC, Peal, DS, Nona Sotoodehnia, R. A. Kronmal, Verschuren WM, de Geus, E.J.C.; id_orcid, B. Isomaa, Lokki, M.L., Albert, C., Hadley, D, Wild, S.H., Lunetta, K.L., Gonneke Willemsen, Isomaa B, Brundel, B.J.J.M., Stricker, B.H., Marques-Vidal, P., James F Wilson, Denis C Shields, Barlassina, Cristina, Stefansson, K., Forouhi, N.G., Albert, CM, Markku S Nieminen, Metspalu A, Cho, Yoon Shin, A. V. Segrè, Caroline Hayward, Willemsen, G, Harris, Tamara B., Hunter, David J., Boomsma, D.I.; id_orcid, Navarro, Pau; id_orcid, Stanton, Alice V, Gudbjartsson, D.F., Boomsma, D., Strachan, D.P., Luben, R., Peter Almgren, Uitterlinden, André; id_orcid, Ben A Oostra, Veronique Vitart, Rudolf A de Boer, Viikari, J, Rudan, Igor, Felix, Stephan B., Beckmann, Jacques S., Smith, George Davey, Luben, RN, Zitting, P., Nancy L Pedersen, Markus MR, Ingrid B Borecki, John B Whitfield, Wijmenga, Cisca, Weedon, Michael N, P. Almgren, Johnson, Toby, Salomaa V, O'Donnell, Christopher J, Rossin, E., Hsueh, WC, J. J. Hottenga, Xie, WJ, André G Uitterlinden, Wheeler W, Arnar, David O., T. Quertermous, Bouchard C, Thorsteinsdottir, U., den Heijer M, Cristina Barlassina, Wiek H van Gilst, Boomsma, DI, Waite, L, Xie, W., C. Dina, Daniele Cusi, Rossin, EJ, Sibon OC, Wong, Quenna, Spector, Tim D, Uitterlinden, A.G., Beckmann JS, K. T. Khaw, Sarah H Wild, Philippe Froguel, Ong, K., PR GWAS Consortium, M. Eijgelsheim, W. Zhang, Peters, A, Montgomery, Grant W., A. Hingorani, Kutalik, Z., Psaty, BM, Kaab, S, Spector TD, Ferrucci L, Feitosa, M.F., Walker, M., Oostra BA, Jaako Tuomilehto, Willemsen, G., Kahonen, M, Andrew B Singleton, Chung, M., Psaty, B.M., Boomsma, D.I., Quertermous, T, Westra, Harm-Jan, Nieminen, Markku S., Sinisalo, J, van der Klauw, Melanie M, Psaty, B., Dina, C, Hwang, S.-J., Kraft P, Grant W Montgomery, Pramstaller, Peter P, Hsueh, W., B. M. Psaty, Wijmenga, Cisca; id_orcid, Rudan, I, Shin, JT, Rudan, D, Vitart, V., Boucher, G., Felix, S.B., Milan DJ, Isaacs A, Junttila, Juhani, Juhani Junttila, Christian Fuchsberger, J. Luan, M. Kähönen, O'Connell, Jeffrey R., Hayward, Caroline; id_orcid, Bruno H Ch Stricker, Verschuren, W M Monique, Jian'an Luan, Heijer, Mariska, Song C, K. W. Knowles, Wendy L McArdle, Polasek, O, Boer, JMA, Wong, Andrew, Angrad S Kooner, Nilesh J Samani, D. Darbar, Ohlsson, Claes, Rizzi, Federica, J. Sinisalo, Milan, D., Stricker, Bruno H. Ch, Boehnke, M., N. G. Martin, Geus, E.J. de, Beckmann, J., U. Ekelund, Philippe Goyette, Jensen, Majken K., Kerr, K.F., Ellinor, P., Snieder, Harold; id_orcid, Shamika Ketkar, Bandinelli, S, Milani L, QRS GWAS Consortium, Sanna, S., J. Viikari, Junttila, J., Uitterlinden, Andre G., O. Polasek, Bianca J J M Brundel, Ketkar, Shamika, Rimm EB, Harm-Jan Westra, Lind, P.A., Song, C., Thorsteinsdottir U, Go, MJ, Sibon, OCM, Groop, L., Ellinor, PT, Sotoodehnia N, Walker, M, Loos, Ruth J F, Khaw KT, Munroe PB, T. Tanaka, Kutalik, Zoltan, Ellinor, P.T., Martin den Heijer, Johansson, Asa, Almgren, P., Timpson, Nicholas J, Hofman, A., Chung M, Lu Qi, Smith, Albert V, Milan, DJ   +999 more
core   +1 more source

Identifying the evolutionary building blocks of the cardiac conduction system.

PLoS ONE, 2012
The endothermic state of mammals and birds requires high heart rates to accommodate the high rates of oxygen consumption. These high heart rates are driven by very similar conduction systems consisting of an atrioventricular node that slows the ...
Bjarke Jensen, Bastiaan J D Boukens, Alex V Postma, Quinn D Gunst, Maurice J B van den Hoff, Antoon F M Moorman, Tobias Wang, Vincent M Christoffels   +7 more
doaj   +1 more source

Innovations and mechanisms in pacing therapy for heart failure [PDF]

, 2022
Despite pharmacological advances, heart failure remains a major cause of mortality and morbidity. Pacing therapy for heart failure was achieved in the 1990s with the advent of biventricular pacing (BVP).
Arnold, Ahranyan
core   +1 more source

Gradual differentiation and confinement of the cardiac conduction system as indicated by marker gene expression

, 2020
The components of the cardiac conduction system, responsible for coordinated activation of the heart chambers, are well defined and their cells differ in gene expression profile and phenotype from those of the surrounding working myocardium.
Christoffels, Vincent M., Stefanovic, Sonia, van Eif, Vincent W. W., Mohan, Rajiv A.   +3 more
core   +2 more sources

Histochemical study of the heart conduction system [PDF]

, 1980
The distribution of acid phosphatase and succinic dehydrogenase in the specialized muscle fibers constructing the heart conduction system (sinoatrial node, atrioventricular node, atrioventricular bundle and Purkinje fibers) and the ordinary heart muscle ...
Tatsuhiko MUKUDAI, Mukudai, Tatsuhiko
core   +1 more source

Differentiation of the Atrioventricular Conducting System of the Heart [PDF]

Circulation, 1961
The structure and function of the atrioventricular conducting system of the heart, and its relationship to the myocardium, are examined from a developmental point of view. On the basis of information derived from electron micrographic, electrophysiologic, and developmental studies of heart tissue, it is concluded that: (1) The idea of the syncytial ...
Ludwig W. Eichna, ROBERT L. DEHAAN
openaire   +2 more sources

Variant Intronic Enhancer Controls SCN10A-Short Expression and Heart Conduction

, 2021
BACKGROUND: Genetic variants in SCN10A, encoding the neuronal voltage-gated sodium channel Na V1.8, are strongly associated with atrial fibrillation, Brugada syndrome, cardiac conduction velocities, and heart rate.
Verkerk, Arie O, Bosada, Fernanda M, Offerhaus, Joost A, Boukens, Bastiaan J, Scholman, Koen T, van Duijvenboden, Karel, Man, Joyce C K, Walsh, Roddy, van Eif, Vincent W W, Bezzina, Connie R, Barnett, Phil, Christoffels, Vincent M   +11 more
core   +1 more source

Conduction Disturbances Associated with TAVR

, 2023
Despite the improvement in the incidence of periprocedural complications associated with transcatheter aortic valve replacement (TAVR), conduction disturbances remain the most frequent complication of TAVR procedures.
Gomez, Camilo A, Ferreira, Alexandre C, Marchena, Eduardo J   +2 more
core   +1 more source