Results 41 to 50 of about 20,033,761 (330)

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders [PDF]

open access: yes, 2011
Elevated resting heart rate is associated with greater risk of cardiovascular disease and mortality. In a 2-stage meta-analysis of genome-wide association studies in up to 181,171 individuals, we identified 14 new loci associated with heart rate and ...
Kooner, A.S.   +999 more
core   +2 more sources

Optimizing S10s Gene Therapy Injection to Restore Ventricular Conduction in a Simplified Heart Failure Model

open access: yes
International audienceGene transfer of a cardiac-specific SCN10A transcript (S10s) is a novel approach for heart failure (HF) patients non-responsive to resynchronization therapy.
Barrera, Carlos, López   +9 more
core   +4 more sources

Hierarchical Physiologic Pacing to Enhance Clinical Outcomes in Conduction System Pacing.

open access: yesHeart Rhythm
BACKGROUND Left bundle branch area pacing (LBBAP) includes left bundle branch pacing (truncal or fascicular) and left ventricular septal pacing (LVSP). Studies show that LBBP provides better outcomes than LVSP in heart failure. OBJECTIVES We classified
S. Ponnusamy   +6 more
semanticscholar   +1 more source

Cardiac conduction system regeneration prevents arrhythmias after myocardial infarction

open access: yesNature Cardiovascular Research
Arrhythmias are a hallmark of myocardial infarction (MI) and increase patient mortality. How insult to the cardiac conduction system causes arrhythmias following MI is poorly understood.
Judy R. Sayers   +13 more
semanticscholar   +1 more source

Typical chest pain and precordial leads ST-elevation in patients with pacemakers - are we always looking at an acute myocardial infarction? [PDF]

open access: yesVojnosanitetski Pregled, 2015
Introduction. Electrocardiographic (ECG) diagnosis of acute myocardial infarction (AMI) in patients with paced rhythm is difficult. Sgarbossa’s criteria represent helpful diagnostic ECG tool. Case report.
Ostojić Marina M.   +4 more
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen   +23 more
wiley   +1 more source

Sinus Bradycardia as a Manifestation of Iron Deficiency Anaemia: A Case Report and Anaesthetic Implications [PDF]

open access: yesJournal of Clinical and Diagnostic Research
Iron Deficiency Anaemia (IDA) is the world’s leading nutritional disorder. While the conventional cardiovascular response to anaemia involves tachycardia due to sympathetic stimulation, anaemia-related autonomic dysfunction may paradoxically present as ...
Dara Lakshmi Harshitha   +4 more
doaj   +1 more source

Radiofrequency ablation of anteroseptal accessory pathway: A challenge to the electrophysiologist [PDF]

open access: yesVojnosanitetski Pregled, 2015
Introduction. Anteroseptal accessory pathways (APs) are located in the apex of the triangle of Koch’s connecting the atrial and ventricular septum in the region of the His bundle. Ablation of anteroseptal pathway locations remains a challenge to
Vukmirović Mihailo   +3 more
doaj   +1 more source

Exercise Capacity, Physical Activity, Fatigue, and Neurocognitive Function in Adult Survivors of Childhood Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Adult survivors of childhood acute lymphoblastic leukemia (ALL) are at risk of reduced exercise capacity, decreased physical activity levels, persistent fatigue, and neurocognitive deficits. The aim was to investigate exercise capacity and physical activity levels of adult survivors of childhood ALL and their associations with ...
Laura Jess   +5 more
wiley   +1 more source

Feasibility and Efficacy of His Bundle Pacing or Left Bundle Pacing Combined With Atrioventricular Node Ablation in Patients With Persistent Atrial Fibrillation and Implantable Cardioverter‐Defibrillator Therapy

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background Persistent atrial fibrillation may lead to a higher probability of inappropriate shocks in heart failure patients with an implantable cardioverter‐defibrillator (ICD). The aim of this study was to evaluate the impact of His‐Purkinje conduction
Songjie Wang   +7 more
doaj   +1 more source

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