Results 21 to 30 of about 188,628 (354)

The cardiac sodium channel displays differential distribution in the conduction system and transmural heterogeneity in the murine ventricular myocardium [PDF]

, 2009
Cardiac sodium channels are responsible for conduction in the normal and diseased heart. We aimed to investigate regional and transmural distribution of sodium channel expression and function in the myocardium.
A. A. M. Wilde, A. O. Verkerk, B. P. Scicluna, C. A. Remme, C. Annink, C. R. Bezzina, J. M. T. Bakker, M. J. B. den Hoff, M. W. Veldkamp, T. A. B. Veen, V. M. Christoffels, W. M. H. Hoogaars, W. T. J. Aanhaanen   +12 more
core   +3 more sources

Incorporating Inductances in Tissue-Scale Models of Cardiac Electrophysiology [PDF]

, 2017
In standard models of cardiac electrophysiology, including the bidomain and monodomain models, local perturbations can propagate at infinite speed.
Balay S., Benson A. P., Boyce E. Griffith, Cattaneo C., Colli Franzone P., DeHaan R. L., Fastl T. E., Jou D., Keener J. P., Krueger M. W., MATLAB, Neu J. C., Sachse F. B., Simone Rossi, ten Tusscher K. H. W. J., Thomas C. E., Tung L., Wikswo J. P.   +17 more
core   +3 more sources

Atrial fibrillation and electrophysiology in transgenic mice with cardiac-restricted overexpression of FKBP12 [PDF]

, 2019
Cardiomyocyte-restricted overexpression of FK506-binding protein 12 transgenic (αMyHC-FKBP12) mice develop spontaneous atrial fibrillation (AF). The aim of the present study is to explore the mechanisms underlying the occurrence of AF in αMyHC-FKBP12 ...
Ai, Tomohiko, Chang, Po-Cheng, Chen, Hanying, Chen, Peng-Sheng, Fishbein, Michael C., Homsi, Mohamed, Li, Bai-Yan, Lin, Shien-Fong, Liu, Jijia, Liu, Ying, Maruyama, Mitsunori, Pan, Zhenwei, Rubart, Michael, Shou, Weinian, Xiao, Deyong   +14 more
core   +1 more source

Two dimensional electrophysiological characterization of human pluripotent stem cell-derived cardiomyocyte system. [PDF]

, 2017
Stem cell-derived cardiomyocytes provide a promising tool for human developmental biology, regenerative therapies, disease modeling, and drug discovery.
Gimzewski, James K, Minami, Itsunari, Nakano, Atsushi, Nakano, Haruko, Nakatsuji, Norio, Scharnhorst, Kelsey S, Stieg, Adam Z, Zhu, Huanqi   +7 more
core   +2 more sources

Prolonged PR interval, first-degree heart block and adverse cardiovascular outcomes: a systematic review and meta-analysis [PDF]

, 2016
Objective: First-degree atrioventricular block is frequently encountered in clinical practice and is generally considered a benign process. However, there is emerging evidence that prolonged PR interval may be associated with adverse outcomes. This study
Barker, Diane, Beynon, Rhys, Buchan, Iain, Kwok, Chun Shing, Loke, Yoon K, Mamas, Mamas A, Morley-Davies, Adrian, Myint, Phyo K, Nolan, James, Patwala, Ashish, Rashid, Muhammad, Satchithananda, Duwarakan   +11 more
core   +1 more source

Engineering a conduction-consistent cardiac patch with rGO/PLCL electrospun nanofibrous membranes and human iPSC-derived cardiomyocytes

Frontiers in Bioengineering and Biotechnology, 2023
The healthy human heart has special directional arrangement of cardiomyocytes and a unique electrical conduction system, which is critical for the maintenance of effective contractions.
Yao Tan, Ying Chen, Tingting Lu, Nevin Witman, Bingqian Yan, Yiqi Gong, Xuefeng Ai, Li Yang, Li Yang, Minglu Liu, Runjiao Luo, Huijing Wang, Stefano Ministrini, Stefano Ministrini, Wei Dong, Wei Wang, Wei Fu, Wei Fu   +17 more
doaj   +1 more source

Malaria and the conducting system of the heart [PDF]

BMJ Case Reports, 2013
We report the case of an adult male patient who was admitted to our hospital with a diagnosis of vivax malaria complicated with renal insufficiency and acute respiratory distress syndrome (ARDS). The patient was treated with intravenous artesunate. He was intubated and mechanically ventilated and taken up for haemodialysis in view of worsening renal ...
Smitha, Bhat, Madhu, Kumar, Jayaprakash, Alva   +2 more
openaire   +2 more sources

Ventricular response during lungeing exercise in horses with lone atrial fibrillation [PDF]

, 2013
Reasons for performing the study Atrial fibrillation (AF) is the most important dysrhythmia affecting performance in horses and has been associated with incoordination, collapse and sudden death.
De Clercq, Dominique, Decloedt, Annelies, Sys, Stanislas, Van Der Vekens, Nicky, van Loon, Gunther, Verheyen, Tinne   +5 more
core   +2 more sources

Typical chest pain and precordial leads ST-elevation in patients with pacemakers - are we always looking at an acute myocardial infarction? [PDF]

Vojnosanitetski Pregled, 2015
Introduction. Electrocardiographic (ECG) diagnosis of acute myocardial infarction (AMI) in patients with paced rhythm is difficult. Sgarbossa’s criteria represent helpful diagnostic ECG tool. Case report.
Ostojić Marina M., Potpara Tatjana S., Polovina Marija M., Ostojić Mladen M., Ostojić Miodrag C.   +4 more
doaj   +1 more source

Regulation of Cardiac Conduction and Arrhythmias by Ankyrin/Spectrin-Based Macromolecular Complexes

Journal of Cardiovascular Development and Disease, 2021
The cardiac conduction system is an extended network of excitable tissue tasked with generation and propagation of electrical impulses to signal coordinated contraction of the heart.
Drew Nassal, Jane Yu, Dennison Min, Cemantha Lane, Rebecca Shaheen, Daniel Gratz, Thomas J. Hund   +6 more
doaj   +1 more source