Results 51 to 60 of about 1,271,305 (362)

Bundle Branch Reentrant Ventricular Tachycardia [PDF]

open access: yes, 2005
Bundle branch reentrant (BBR) tachycardia is an uncommon form of ventricular tachycardia (VT) incorporating both bundle branches into the reentry circuit.
Kusniec, Jairo   +2 more
core   +2 more sources

Rheumatic Complete Atrioventricular Block: A Case Report [PDF]

open access: yes, 2020
Acute rheumatic fever is a well-known disease that is still widely observed in developing countries, including our country Morocco. It is known that the majority of patients diagnosed with acute rheumatic fever display abnormalities of the conduction ...
Azzouzi, Leila   +4 more
core   +2 more sources

Elucidation of interface interactions between a dehydratase domain and an acyl carrier protein in cremimycin polyketide synthase

open access: yesFEBS Letters, EarlyView.
In modular polyketide synthases, the dehydratase (DH) domain catalyzes the dehydration reaction of the β‐hydroxyacyl unit attached to the cognate acyl carrier protein (ACP) domain. However, it is unclear how DH interacts with ACP during the reaction. In this study, we identified DH–ACP interface residues, providing the first detailed insights into DH ...
Kaede Kotagiri   +8 more
wiley   +1 more source

Predicting Ejection Fraction from Chest X-rays Using Computer Vision for Diagnosing Heart Failure [PDF]

open access: yesarXiv, 2022
Heart failure remains a major public health challenge with growing costs. Ejection fraction (EF) is a key metric for the diagnosis and management of heart failure however estimation of EF using echocardiography remains expensive for the healthcare system and subject to intra/inter operator variability.
arxiv  

Cardiac Arrhythmias In Congenital Heart Diseases [PDF]

open access: yes, 2009
Arrhythmias figure prominently among the complications encountered in the varied and diverse population of patients with congenital heart disease, and are the leading cause of morbidity and mortality. The incidence generally increases as the patient ages,
Balaji, Seshadri, Khairy, Paul
core   +2 more sources

T-box transcription factor 3 governs a transcriptional program for the function of the mouse atrioventricular conduction system

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2020
Significance Genome-wide association studies have identified common noncoding variants associated with ECG parameters in the TBX3 locus, suggesting that a modest change in TBX3/Tbx3 expression level affects heart function. We characterized the morphology,
Rajiv A. Mohan   +14 more
semanticscholar   +1 more source

Characteristics of the Kelch domain containing (KLHDC) subfamily and relationships with diseases

open access: yesFEBS Letters, EarlyView.
The Kelch protein superfamily includes 63 members, with the KLHDC subfamily having 10 proteins. While their functions are not fully understood, recent advances in KLHDC2's structure and role in protein degradation have highlighted its potential for drug development, especially in PROTAC therapies.
Courtney Pilcher   +6 more
wiley   +1 more source

Doctor of Philosophy [PDF]

open access: yes, 2015
dissertationThis body of work aims at establishing an approach for intraoperative discrimination of cardiac tissue types based on fiber-optics confocal microscopy (FCM). An important application of this approach is in pediatric heart surgery.
Huang, Chao
core  

High resolution 3-Dimensional imaging of the human cardiac conduction system from microanatomy to mathematical modeling [PDF]

open access: yes, 2017
Cardiac arrhythmias and conduction disturbances are accompanied by structural remodelling of the specialised cardiomyocytes known collectively as the cardiac conduction system.
A Atkinson   +49 more
core   +1 more source

Immunoregulatory mechanisms of the arachidonic acid pathway in cancer

open access: yesFEBS Letters, EarlyView.
The central role of the arachidonic acid (AA) pathway in anticancer immunity. Enzymes and metabolites of the AA pathway can play both immunosuppressive and immunostimulatory roles in the tumor microenvironment. Therefore, their tailored targeting could be beneficial as a standalone therapy or in combination with current cancer immunotherapy.
Maria Tredicine   +3 more
wiley   +1 more source

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