Results 51 to 60 of about 1,271,305 (362)
Bundle Branch Reentrant Ventricular Tachycardia [PDF]
Bundle branch reentrant (BBR) tachycardia is an uncommon form of ventricular tachycardia (VT) incorporating both bundle branches into the reentry circuit.
Kusniec, Jairo+2 more
core +2 more sources
Rheumatic Complete Atrioventricular Block: A Case Report [PDF]
Acute rheumatic fever is a well-known disease that is still widely observed in developing countries, including our country Morocco. It is known that the majority of patients diagnosed with acute rheumatic fever display abnormalities of the conduction ...
Azzouzi, Leila+4 more
core +2 more sources
In modular polyketide synthases, the dehydratase (DH) domain catalyzes the dehydration reaction of the β‐hydroxyacyl unit attached to the cognate acyl carrier protein (ACP) domain. However, it is unclear how DH interacts with ACP during the reaction. In this study, we identified DH–ACP interface residues, providing the first detailed insights into DH ...
Kaede Kotagiri+8 more
wiley +1 more source
Predicting Ejection Fraction from Chest X-rays Using Computer Vision for Diagnosing Heart Failure [PDF]
Heart failure remains a major public health challenge with growing costs. Ejection fraction (EF) is a key metric for the diagnosis and management of heart failure however estimation of EF using echocardiography remains expensive for the healthcare system and subject to intra/inter operator variability.
arxiv
Cardiac Arrhythmias In Congenital Heart Diseases [PDF]
Arrhythmias figure prominently among the complications encountered in the varied and diverse population of patients with congenital heart disease, and are the leading cause of morbidity and mortality. The incidence generally increases as the patient ages,
Balaji, Seshadri, Khairy, Paul
core +2 more sources
Significance Genome-wide association studies have identified common noncoding variants associated with ECG parameters in the TBX3 locus, suggesting that a modest change in TBX3/Tbx3 expression level affects heart function. We characterized the morphology,
Rajiv A. Mohan+14 more
semanticscholar +1 more source
Characteristics of the Kelch domain containing (KLHDC) subfamily and relationships with diseases
The Kelch protein superfamily includes 63 members, with the KLHDC subfamily having 10 proteins. While their functions are not fully understood, recent advances in KLHDC2's structure and role in protein degradation have highlighted its potential for drug development, especially in PROTAC therapies.
Courtney Pilcher+6 more
wiley +1 more source
dissertationThis body of work aims at establishing an approach for intraoperative discrimination of cardiac tissue types based on fiber-optics confocal microscopy (FCM). An important application of this approach is in pediatric heart surgery.
Huang, Chao
core
High resolution 3-Dimensional imaging of the human cardiac conduction system from microanatomy to mathematical modeling [PDF]
Cardiac arrhythmias and conduction disturbances are accompanied by structural remodelling of the specialised cardiomyocytes known collectively as the cardiac conduction system.
A Atkinson+49 more
core +1 more source
Immunoregulatory mechanisms of the arachidonic acid pathway in cancer
The central role of the arachidonic acid (AA) pathway in anticancer immunity. Enzymes and metabolites of the AA pathway can play both immunosuppressive and immunostimulatory roles in the tumor microenvironment. Therefore, their tailored targeting could be beneficial as a standalone therapy or in combination with current cancer immunotherapy.
Maria Tredicine+3 more
wiley +1 more source