Results 101 to 110 of about 11,708,753 (340)

Fabry disease and the heart

Best Practice & Research Clinical Endocrinology & Metabolism, 2015
Fabry disease is induced by a mutation in the alpha-galactosidase A gene, causing a deficiency of the enzyme alpha-galactosidase A. (1) The enzyme defect leads to progressive intracellular accumulation of globotriaosylceramide in lysosomes of various tissues and organs, including heart, kidney and nerve system.
Frank Weidemann, Christoph Wanner, Nora Seydelmann, Stefan Störk, Georg Ertl   +4 more
openaire   +3 more sources

Clinical Characteristics of Parkinsonism in HTLV‐1‐Associated Myelopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Human T‐lymphotropic virus type 1 (HTLV‐1)‐associated myelopathy/tropical spastic paraparesis (HAM/TSP) is the classic neurological manifestation of HTLV‐1 infection; however, this virus has also been associated with other neurological disorders. Concurrent parkinsonism is relatively rare and presents diagnostic challenges.
Mika Dozono, Satoshi Nozuma, Shota Hirakata, Takashi Yoshida, Daisuke Kodama, Masakazu Tanaka, Eiji Matsuura, Ryuji Kubota, Hiroshi Takashima   +8 more
wiley   +1 more source

Innovative Artificial Neural Networks-Based Decision Support System for Heart Diseases Diagnosis

, 2013
Heart diagnosis is not always possible at every medical center, especially in the rural areas where less support and care, due to lack of advanced heart diagnosis equipment.
S. Ghwanmeh, A. Mohammad, A. Al-Ibrahim
semanticscholar   +1 more source

Current state of knowledge on aetiology, diagnosis, management, and therapy of myocarditis: a position statement of the European Society of Cardiology Working Group on Myocardial and Pericardial Diseases.

European Heart Journal, 2013
In this position statement of the ESC Working Group on Myocardial and Pericardial Diseases an expert consensus group reviews the current knowledge on clinical presentation, diagnosis and treatment of myocarditis, and proposes new diagnostic criteria for ...
A. Caforio, S. Pankuweit, E. Arbustini, C. Basso, J. Gimeno-Blanes, S. Felix, M. Fu, T. Heliö, S. Heymans, R. Jahns, K. Klingel, A. Linhart, B. Maisch, W. McKenna, J. Mogensen, Y. Pinto, A. Ristic, H. Schultheiss, H. Seggewiss, L. Tavazzi, G. Thiene, A. Yilmaz, P. Charron, P. Elliott   +23 more
semanticscholar   +1 more source

The Comparative Effectiveness and Tolerability of Sphingosine‐1‐Phosphate Receptor Modulators in Patients With Multiple Sclerosis: A Network Meta‐Analysis of Randomized Controlled Trials

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Sphingosine‐1‐phosphate receptor modulators (S1PRM) are used to treat relapsing multiple sclerosis (MS). Each drug has a different S1PR‐subtype selectivity. They target the G‐protein coupled S1P receptors and exert significant immunomodulatory effects, such as preventing the formation of new CNS lesions and the reactivation of pre ...
Faizan Shahzad, Taimoon Rasheed, Momina Riaz Siddiqui, Hamza Hamid, Marwah Bintay Khalid, Haroon Shabbir, Besher Shami, Abdullah, Syed Ijlal Ahmed   +8 more
wiley   +1 more source

Sex-based association between high-density lipoprotein cholesterol and adverse outcomes after coronary artery bypass grafting

BMC Cardiovascular Disorders
Background High-density lipoprotein cholesterol (HDL-C) is shown to be an independent protective factor against coronary artery diseases (CAD). Yet there are limited studies focusing on the association between HDL-C and coronary artery bypass graft (CABG)
Sara Montazeri Namin, Ali Moradi, Hamed Tavolinejad, Ali Vasheghani-Farahani, Arash Jalali, Mina Pashang, Saeed Sadeghian, Jamshid Bagheri, Soheil Mansourian, Mehdi Mehrani, Kaveh Hosseini, Sina Rashedi, Masih Tajdini   +12 more
doaj   +1 more source

Antibiotic appropriateness and adherence to local guidelines in perioperative prophylaxis: results from an antimicrobial stewardship intervention

Antimicrobial Resistance and Infection Control, 2020
Objectives Surgical antibiotic prophylaxis (SAP) represents a major indication of antibiotic consumption worldwide. The present study aims to report the results of an enabling, long-term AMS intervention conducted between 2013 and 2019 on an Italian ...
Francesco Vladimiro Segala, Rita Murri, Eleonora Taddei, Francesca Giovannenze, Pierluigi Del Vecchio, Emanuela Birocchi, Francesco Taccari, Roberto Cauda, Massimo Fantoni   +8 more
doaj   +1 more source

Discovery and Treatment of Action Potential‐Independent Myotonia in Hyperkalemic Periodic Paralysis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hyperkalemic periodic paralysis (hyperKPP) is characterized by attacks of transient weakness. A subset of hyperKPP patients suffers from transient involuntary contraction of muscle (myotonia). The goal of this study was to determine mechanisms causing myotonia in hyperKPP.
Chris Dupont, Adam Deardorff, Murad Nawaz, Andrew A. Voss, Mark M. Rich   +4 more
wiley   +1 more source

Depleted iron stores are associated with inspiratory muscle weakness independently of skeletal muscle mass in men with systolic chronic heart failure

Journal of Cachexia, Sarcopenia and Muscle, 2018
Background Skeletal and respiratory muscle dysfunction constitutes an important pathophysiological feature of heart failure (HF). We assessed the relationships between respiratory muscle function, skeletal muscle mass, and physical fitness in men with HF
Michał Tkaczyszyn, Marcin Drozd, Kinga Węgrzynowska‐Teodorczyk, Irena Flinta, Kamil Kobak, Waldemar Banasiak, Piotr Ponikowski, Ewa A. Jankowska   +7 more
doaj   +1 more source

Heart disease and stroke statistics--2008 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee.

Circulation, 2007
1. About These Statistics…e70 2. Cardiovascular Diseases…e72 3. Coronary Heart Disease, Acute Coronary Syndrome, and Angina Pectoris…e89 4. Stroke…e99 5. High Blood Pressure…e111 6. Congenital Cardiovascular Defects…e116 7.
W. Rosamond, K. Flegal, K. Furie, A. Go, K. Greenlund, Nancy Haase, S. Hailpern, Michael Ho, V. Howard, B. Kissela, S. Kittner, D. Lloyd‐Jones, M. McDermott, J. Meigs, C. Moy, G. Nichol, Christopher J O'Donnell, V. Roger, P. Sorlie, J. Steinberger, T. Thom, M. Wilson, Yuling Hong   +22 more
semanticscholar   +1 more source