Results 61 to 70 of about 107,286 (246)

Isosorbide dinitrate, with or without hydralazine, does not reduce wave reflections, left ventricular hypertrophy, or myocardial fibrosis in patients with heart failure with preserved ejection fraction [PDF]

, 2017
Background-Wave reflections, which are increased in patients with heart failure with preserved ejection fraction, impair diastolic function and promote pathologic myocardial remodeling.
Akers, Scott, Beraun, Melissa, Chirinos, Julio A., Chittams, Jesse, Haines, Philip G., Koppula, Maheswara R., Rawat, Deepa, Segers, Patrick, Shiva-Kumar, Prithvi, Soto-Calderon, Haideliza, Townsend, Raymond R., Varakantam, Swapna, Witschey, Walter R., Zamani, Payman   +13 more
core   +1 more source

A Computational Journey Toward an Optimal Design for Metamaterial Epicardial Passive Sleeves

Advanced Healthcare Materials, EarlyView.
Passive epicardial sleeves are evaluated in 3D in‐silico heart models to reveal how sleeve geometry, stiffness, anisotropy, and metamaterial architecture influence cardiac mechanics after myocardial infarction. A continuum‐to‐auxetic design exploration shows that region‐specific mechanical engagement can reduce infarct bulging and modulate torsional ...
Vahid Naeini, Emilio A. Mendiola, Ahmad Rafsanjani, Fergal B. Coulter, Qian Xiang, Jianyi Zhang, Peter Vanderslice, Vahid Serpooshan, Reza Avazmohammadi   +8 more
wiley   +1 more source

Translational Considerations for Injectable Biomaterials and Bioscaffolds to Repair and Regenerate Brain Tissue

Advanced Healthcare Materials, EarlyView.
The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley   +1 more source

Bioprinting Organs—Science or Fiction?—A Review From Students to Students

Advanced Healthcare Materials, EarlyView.
Bioprinting artificial organs has the potential to revolutionize the medical field. This is a comprehensive review of the bioprinting workflow delving into the latest advancements in bioinks, materials and bioprinting techniques, exploring the critical stages of tissue maturation and functionality.
Nicoletta Murenu, Camilla Mussoni, Mateo S. Andrade Mier, Paula Buettner, Nathaly Chicaiza‐Cabezas, Yi‐Yu Robin Dai, Jessica Faber, Maren Fiedler, Zan Lamberger, Xuen Jen Ng, Vanessa Moessler, Anna Rederer, Jonas Roeder, Sabrina Stecher, Katinka Theis, Jeanette Weigelt, Silvia Budday, Gregor Lang, Natascha Schaefer   +18 more
wiley   +1 more source

A case report of a patient with heart failure with preserved ejection fraction presented as dysphagia

ESC Heart Failure, 2023
Dysphagia is a common clinical symptom in older people that can be attributed to a wide range of diseases, extending from neoplasm to gastroesophageal reflux diseases such as stroke or achalasia.
Elena Leonidou, Maria Ioannou, Petros Mavrommatis, Angeliki Mouzarou   +3 more
doaj   +1 more source

Identifying Pathophysiological Mechanisms in Heart Failure With Reduced Versus Preserved Ejection Fraction [PDF]

, 2018
Background: Information on the pathophysiological differences between heart failure with reduced ejection fraction (HFrEF) versus heart failure with preserved ejection fraction (HFpEF) is needed Objectives: The purpose of this study was to establish ...
Anker, Stefan D., Cleland, John G. F., Dickstein, Kenneth, Filippatos, Gerasimos S., Hillege, Hans L., Lang, Chim, Metra, Marco, Ng, Leong Loke, Ouwerkerk, Wouter, Ponikowski, Piotr, Samani, Nilesh J., Tromp, Jasper, van der Harst, Pim, van der Meer, Peter, van Veldhuisen, Dirk Jan, Voors, Adriaan A., Westenbrink, Daan, Zannad, Faiez, Zwinderman, Aelko H.   +18 more
core   +3 more sources

Automated echocardiographic detection of heart failure with preserved ejection fraction using artificial intelligence [PDF]

, 2023
Background: Detection of heart failure with preserved ejection fraction (HFpEF) involves integration of multiple imaging and clinical features which are often discordant or indeterminate. Objectives: We applied artificial intelligence (AI) to analyze a
Akerman, A.P., Akerman, A.P., Arystan, A.Z., Arystan, A.Z., Beqiri, A., Beqiri, A., Chartsiad, A., Chartsiad, A., Hawkes, W., Hawkes, W., Huntley, G.D., Huntley, G.D., Kane, G.C., Kane, G.C., Leeson, P., Leeson, P., Lopez-Jimenez, F., Lopez-Jimenez, F., O'Driscoll, J., O'Driscoll, J., Pellikka, P.A., Pellikka, P.A., Pislaru, S.V., Pislaru, S.V., Porumb, M., Porumb, M., Ryu, A.J., Ryu, A.J., Sarwar, R., Sarwar, R., Scott, C.G., Scott, C.G., Upton, R., Upton, R., Woodward, G., Woodward, G.   +35 more
core   +1 more source

Recombinant Proteins: A Molecular Tool to Understand Marine Adhesion and to Advance Biomaterials

Advanced Healthcare Materials, EarlyView.
The production of recombinant proteins represents a fundamental step in the characterisation of marine invertebrate adhesives and in the development of bio‐inspired glues. The association of these proteins with other components such as ions, proteins, polysaccharides, or polymers enables the fabrication of biomaterials for various healthcare ...
Alessandra Whaite, Emilie Duthoo, Mathilde Lefevre, Elise Hennebert, Patrick Flammang   +4 more
wiley   +1 more source

Cardiac metabolism — A promising therapeutic target for heart failure [PDF]

, 2017
Both heart failure with reduced ejection fraction (HFrEF) and with preserved ejection fraction (HFpEF) are associated with high morbidity and mortality.
Frenneaux, Michael P, Loudon, Brodie L, Madhani, Melanie, Noordali, Hannah   +3 more
core   +2 more sources

A deep learning model for early risk prediction of heart failure with preserved ejection fraction by DNA methylation profiles combined with clinical features [PDF]

, 2022
Xuetong Zhao, Yang Sui, Xiuyan Ruan, Xinyue Wang, Kunlun He, Wei Dong, Hongzhu Qu, Xiangdong Fang   +7 more
openalex   +1 more source