Results 71 to 80 of about 2,058,358 (352)

Semaglutide and cardiovascular outcomes in patients with obesity and prevalent heart failure: a prespecified analysis of the SELECT trial [PDF]

Background: Semaglutide, a GLP-1 receptor agonist, reduces the risk of major adverse cardiovascular events (MACE) in people with overweight or obesity, but the effects of this drug on outcomes in patients with atherosclerotic cardiovascular disease and ...
Abe M., Abhaichand R. K., Abhayaratna W. P., Abhyankar A., Abidin I. B. Z., Abou Assi H., Accini Mendoza J. L., Adas M., Agaiby J. M., Agarwal D. K., Agha M., Ahmed A., Ahtiainen P., Aigner E., Ajay N., Al-Karadsheh A., Al-Zoebi A., Ali N., Allison D. C., Allison R., Alpenidze D., Altuntas Y., Ambuj R., Amerena J., Anderson R. J., Ando T., Andrews R., Antonova E., Appel K. F., Arantes F. B., Araz M., Arbel Y., Arenas León J. L., Argyrakopoulou G., Ariani M., Arias Mendoza M. A., Arif A. A., Arneja J., Aroda V. R., Aronne L. J., Arstall M., Asamoah N., Asanin M., Audish H., Avram R., Badat A., Badiu C. V., Bakdash W., Bakiner O. S., Bandezi V. N., Bang L. H., Bansal S., Baranyai M., Barbarash O., Barber M., Barnum O., Barone Rochette G., Bashkin A., Baum S., Bays H. E., Bazzoni Ruiz A. E., Beckowski M., Beerachee Y., Bellary S., Belousova L., Berk M., Bernstein M., Berra C., Beshay I., Bhagwat A., Bhan A., Biggs W. C., Billings L., Bitar F., Block B., Bo S., Bogdanski P., Bolshakova O. O., Boshchenko A. A., Bosworth H., Buscemi S., Colhoun H. M., Deanfield J., Emerson S. S., Frenkel O., Goudev A., Hardt-Lindberg S., Hovingh G. K., Kahn S. E., Kosiborod M. N., Lang C. C., Lincoff A. M., Lingvay I., Pietilä M., Plutzky J., Rasmussen S., Ryan D., Scirica B. M., Urina-Triana M., Verma S., Weeke P. E.   +100 more
core   +9 more sources

SimLVSeg: Simplifying Left Ventricular Segmentation in 2D+Time Echocardiograms with Self- and Weakly-Supervised Learning [PDF]

arXiv, 2023
Echocardiography has become an indispensable clinical imaging modality for general heart health assessment. From calculating biomarkers such as ejection fraction to the probability of a patient's heart failure, accurate segmentation of the heart structures allows doctors to assess the heart's condition and devise treatments with greater precision and ...
arxiv  

Contemporary management of heart failure in the elderly [PDF]

, 2019
The foundation of the treatment of heart failure with reduced ejection fraction is a number of pharmacotherapies shown to reduce morbidity and mortality in large randomised multinational clinical trials.
Jhund, Pardeep S., Osmanska, Joanna
core   +1 more source

Biologically‐Inspired Melt Electrowriting for the Generation of Highly Biomimetic Functional Myocardium

Advanced Functional Materials, EarlyView.
In this work, melt electrowriting is used to fabricate a 3D printed scaffold design that generates engineered cardiac tissues with in‐plane contraction, mimicking natural myocardium. It is shown that these tissues display advanced maturation and functionality.
Olalla Iglesias‐García, María Flandes‐Iparraguirre, Pilar Montero‐Calle, Ricardo M. Rosales, Asier Ullate‐Agote, Andrea Sánchez‐Bueno, Eduardo Larequi, Ilazki Anaut‐Lusar, Nicolás Laita, Aida Oliván‐Viguera, Elena Iglesias, Gloria Abizanda, Patxi San Martín‐Úriz, Paula Aguirre‐Ruiz, Xabier L. Aranguren, Manuel García de Yébenes, Juan José Gavira, Miguel Ángel Martínez, Estefanía Peña, Manuel Doblaré, Elena M. de‐Juan‐Pardo, Esther Pueyo, Felipe Prosper, Manuel M. Mazo Vega   +23 more
wiley   +1 more source

A case report of a patient with heart failure with preserved ejection fraction presented as dysphagia

ESC Heart Failure, 2023
Dysphagia is a common clinical symptom in older people that can be attributed to a wide range of diseases, extending from neoplasm to gastroesophageal reflux diseases such as stroke or achalasia.
Elena Leonidou, Maria Ioannou, Petros Mavrommatis, Angeliki Mouzarou   +3 more
doaj   +1 more source

Tunable Thermoshrinkable Hydrogels for 4D Fabrication of Cell‐Seeded Channels

Advanced Functional Materials, EarlyView.
A thermoresponsive polymer with methacrylate groups for photo‐cross‐linking, based on polyethylene glycol, N‐isopropylacrylamide, and 2‐hydroxyethyl acrylate is synthetized to yield hydrogels that shrink upon temperature increase. The new polymer enables the fabrication of cell‐laden perfusable channels with diameters below 200 µm by combining ...
Greta Di Marco, Marc Falandt, Myriam Neumann, Martina Viola, Thibault Sampon, Marta G. Valverde, Anne Metje van Genderen, Silvia M. Mihaila, Cornelus F. van Nostrum, Bas G. P. van Ravensteijn, Riccardo Levato, Rosalinde Masereeuw, Tina Vermonden   +12 more
wiley   +1 more source

Similarities and Differences Between HFmrEF and HFpEF

Frontiers in Cardiovascular Medicine, 2021
The new guidelines classify heart failure (HF) into three subgroups based on the ejection fraction (EF): HF with reduced EF (HFrEF), HF with mid-range EF (HFmrEF), and HF with preserved EF (HFpEF).
Peixin Li, Peixin Li, Peixin Li, Hengli Zhao, Hengli Zhao, Hengli Zhao, Hengli Zhao, Jianyu Zhang, Yunshan Ning, Yan Tu, Dingli Xu, Dingli Xu, Dingli Xu, Qingchun Zeng, Qingchun Zeng, Qingchun Zeng   +15 more
doaj   +1 more source

EchoGNN: Explainable Ejection Fraction Estimation with Graph Neural Networks [PDF]

arXiv, 2022
Ejection fraction (EF) is a key indicator of cardiac function, allowing identification of patients prone to heart dysfunctions such as heart failure. EF is estimated from cardiac ultrasound videos known as echocardiograms (echo) by manually tracing the left ventricle and estimating its volume on certain frames.
arxiv  

3D Microtumors Representing Ovarian Cancer Minimal Residual Disease Respond to the Fatty Acid Oxidation Inhibitor Perhexiline

Advanced Healthcare Materials, EarlyView.
Minimal residual disease (MRD) leads to cancer relapse and poor survival in ovarian cancer. The lack of representative 3D models limits therapy development. The microfluidics‐based high throughput 3D microtumor platform described here generates clinically‐relevant MRD models. The 3D microtumors recapitulate the molecular signatures of MRD from patients.
Xingyun Yang, Mara Artibani, Yongcheng Jin, Aneesh Aggarwal, Yujia Zhang, Sandra Muñoz‐Galvan, Ellina Mikhailova, Lena Rai, Nobina Mukherjee, Ravinash Krishna Kumar, Ashwag Albukhari, Shaohua Ma, Linna Zhou, Ahmed Ashour Ahmed, Hagan Bayley   +14 more
wiley   +1 more source

Management, survival, and predictors of mortality among hospitalized heart failure patients at Debre Markos comprehensive specialized hospital, Northwest Ethiopia: Prospective cohort study

SAGE Open Medicine, 2021
Introduction: Heart failure is a major public health problem worldwide. Since heart failure with reduced ejection fraction and preserved ejection fraction are different clinical entities, in-hospital mortality may occur at different rates.
Bekalu Kebede, Melese Getachew, Yalew Molla, Bereket Bahiru, Bekalu Dessie   +4 more
doaj   +1 more source