Vericiguat for Heart Failure with Reduced Ejection Fraction [PDF]
AbstractPurpose of ReviewThe nitric oxide (NO)-soluble guanylate cyclase (sGC)-cyclic guanosine monophosphate (cGMP) pathway plays an important role in the regulation of cardiovascular function, and it is disrupted in heart failure (HF), resulting in decreased protection against myocardial injury.
Lombardi C. M.+11 more
openaire +4 more sources
Advanced heart failure with reduced ejection fraction [PDF]
Patients suffering advanced heart failure with reduced ejection fraction (HFrEF) account for a large portion of patients admitted to hospitals worldwide. Mortality and 30-day readmission rates for HFrEF are now a focus of value-based payment models, making management of this disease a priority for hospitals, physicians, and payers alike.
Albert Hicks+5 more
openaire +3 more sources
A facilitated home-based cardiac rehabilitation intervention for people with heart failure and their caregivers:a research programme including the REACH-HF RCT [PDF]
Background: Rates of participation in centre (hospital)-cardiac rehabilitation by patients with heart failure are suboptimal. Heart failure has two main phenotypes differing in underlying pathophysiology: Heart failure with reduced ejection fraction is ...
Abraham, Charles+20 more
core +3 more sources
Heart failure and mental health conditions frequently coexist and have a negative impact on health-related quality of life and prognosis. We aimed to evaluate depression and anxiety symptoms and to determine the association between psychological distress
Timea Magdolna Szabo+6 more
doaj +1 more source
Sex differences and atrial fibrillation in heart failure with reduced versus preserved ejection fraction [PDF]
Heart failure is a major public health problem. Patients with heart failure often experience dyspnoea, fatigue and/or have peripheral oedema. The prognosis of heart failure remains poor, with a severely impaired quality of life, frequent hospitalizations
Santema, Bernadet
core +1 more source
Metabolomics and a Breath Sensor Identify Acetone as a Biomarker for Heart Failure
Background: Multi-omics delivers more biological insight than targeted investigations. We applied multi-omics to patients with heart failure with reduced ejection fraction (HFrEF).
Patrick A. Gladding+15 more
doaj +1 more source
Echocardiographic characterization of heart failure [PDF]
Heart failure is a highly prevalent disease. In failure, the pump function of the heart is insufficient, leading to symptoms such as shortness of breath and fluid retention. Echocardiography is commonly used to diagnose heart failure.
Nauta, Jan F
core +1 more source
Aims The relationship between diabetic microvascular complications and the incidence of two types of heart failure—heart failure with reduced ejection fraction (HFrEF) (left ventricular ejection fraction [LVEF]
Mayu Tochiya+11 more
doaj +1 more source
Prevalence of Iron Deficiency in Patients of Heart Failure with Reduced Ejection Fraction and Response to Injectable Iron Therapy- A Hospital Based Observational Study [PDF]
Aim of the Study: To estimate the prevalence of iron deficiency in patients of heart failure with reduced ejection fraction & response to injectable iron therapy in patients with iron deficiency anemia in heart failure with reduced ejection fraction.
Anoop Kumar Singh+2 more
core +3 more sources
Heart Failure With Mid-range Ejection Fraction: Every Coin Has Two Sides
This review summarizes current knowledge regarding clinical epidemiology, pathophysiology, and prognosis for patients with HFmrEF in comparison to HFrEF and HFpEF. Although recommended treatments currently focus on aggressive management of comorbidities,
Kaiyuan Zhu+8 more
doaj +1 more source