Results 41 to 50 of about 264,442 (390)

Heart failure with preserved ejection fraction. [PDF]

, 2012
Heart failure with preserved ejection fraction (HFpEF) has recently emerged as a major cause of cardiovascular morbidity and mortality. Contrary to initial beliefs, HFpEF is now known to be as common as heart failure with reduced ejection fraction (HFrEF)
ElGuindy, A, Yacoub, MH
core   +1 more source

Empagliflozin in Heart Failure with a Preserved Ejection Fraction.

New England Journal of Medicine, 2021
BACKGROUND Sodium-glucose cotransporter 2 inhibitors reduce the risk of hospitalization for heart failure in patients with heart failure and a reduced ejection fraction, but their effects in patients with heart failure and a preserved ejection fraction ...
S. Anker, J. Butler, G. Filippatos, J. Ferreira, E. Bocchi, M. Böhm, H. Brunner-la Rocca, D. Choi, V. Chopra, E. Chuquiure-Valenzuela, N. Giannetti, J. Gómez-Mesa, S. Janssens, J. Januzzi, J. González-Juanatey, B. Merkely, S. Nicholls, S. Perrone, I. Piña, P. Ponikowski, M. Senni, D. Sim, J. Špinar, I. Squire, S. Taddei, H. Tsutsui, S. Verma, D. Vinereanu, Jian Zhang, P. Carson, Carolyn S. P. Lam, N. Marx, C. Zeller, N. Sattar, W. Jamal, S. Schnaidt, J. Schnee, M. Brueckmann, S. Pocock, F. Zannad, M. Packer   +40 more
semanticscholar   +1 more source

The diagnostic value of peroxisome proliferator-activated receptor-γ coactivator-1α in identifying different chronic heart failure phenotypes

Frontiers in Cardiovascular Medicine, 2022
BackgroundDespite advances in diagnosing and treating chronic heart failure (HF), the underlying mechanisms in different HF phenotypes remain unclear. Mitochondrial energy metabolism is crucial in HF etiology.
Shiwen Zhang, Shiwen Zhang, Yufei Zhou, Yanfang Ma, Zhan Li, Yinglong Hou, Yinglong Hou   +6 more
doaj   +1 more source

Baseline characteristics and treatment of patients in prospective comparison of ARNI with ACEI to determine impact on global mortality and morbidity in heart failure trial (PARADIGM-HF) [PDF]

, 2014
Aim<p></p> To describe the baseline characteristics and treatment of the patients randomized in the PARADIGM-HF (Prospective comparison of ARNi with ACEi to Determine Impact on Global Mortality and morbidity in Heart Failure) trial, testing ...
Adel R. Rizkala, Akshay S Desai, Jean L. Rouleau, Jianjian Gong, John J. V. McMurray, Karl Swedberg, Martin Lefkowitz, Michael R. Zile, Milton Packer, null null, Scott D. Solomon, Victor C. Shi   +11 more
core   +3 more sources

SGLT2 inhibitors in heart failure with reduced ejection fraction [PDF]

The Egyptian Heart Journal, 2021
AbstractSodium – glucose co-transporter 2 (SGLT2) inhibitors reduce blood glucose by inhibiting reabsorption of glucose from the proximal renal tubules. Initial studies showed that apart from reducing blood glucose they also reduce the combined endpoint of myocardial infarction, stroke, and cardiovascular death, hospitalization from heart failure, and ...
U. Das, A Paul, Suvro Banerjee
openaire   +3 more sources

Association of ambient temperature and acute heart failure with preserved and reduced ejection fraction

ESC Heart Failure, 2022
Aims Evidence on the association between ambient temperature and the onset of acute heart failure (AHF) is scarce and mixed. We sought to investigate the incidence of AHF admissions based on ambient temperature change, with particular interest in ...
Takahiro Jimba, Shun Kohsaka, Masao Yamasaki, Toshiaki Otsuka, Kazumasa Harada, Yasuyuki Shiraishi, Shinji Koba, Makoto Takei, Takashi Kohno, Kenichi Matsushita, Tetsuro Miyazaki, Satoshi Kodera, Shigeto Tsukamoto, Kiyoshi Iida, Akito Shindo, Daisuke Kitano, Takeshi Yamamoto, Ken Nagao, Morimasa Takayama, Tokyo CCU Network Scientific Committee   +19 more
doaj   +1 more source

Effect of a Hospital and Postdischarge Quality Improvement Intervention on Clinical Outcomes and Quality of Care for Patients With Heart Failure With Reduced Ejection Fraction: The CONNECT-HF Randomized Clinical Trial.

Journal of the American Medical Association (JAMA), 2021
Importance Adoption of guideline-directed medical therapy for patients with heart failure is variable. Interventions to improve guideline-directed medical therapy have failed to consistently achieve target metrics, and limited data exist to inform ...
A. DeVore, B. Granger, G. Fonarow, H. Al-Khalidi, N. Albert, E. Lewis, J. Butler, I. Piña, L. Allen, C. Yancy, L. Cooper, G. Felker, L. Kaltenbach, A. Mcrae, D. Lanfear, R. Harrison, Maghee Disch, D. Ariely, Julie M. Miller, C. Granger, Adrian F. Hernandez   +20 more
semanticscholar   +1 more source

Insulin Resistance Is Associated With Heart Failure With Recovered Ejection Fraction in Patients Without Diabetes

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022
Background Because of advances in medical treatments, a substantial proportion of patients with heart failure (HF) have experienced recovery of ejection fraction (EF), termed HF with recovered EF (HFrecEF).
Chen Die Yang, Wen Qi Pan, Shuo Feng, Jin Wei Quan, Jia Wei Chen, Xin Yi Shu, Muladili Aihemaiti, Feng Hua Ding, Wei Feng Shen, Lin Lu, Rui Yan Zhang, Xiao Qun Wang   +11 more
doaj   +1 more source

‘Hearts and minds’: association, causation and implication of cognitive impairment in heart failure [PDF]

, 2015
The clinical syndrome of heart failure is one of the leading causes of hospitalisation and mortality in older adults. An association between cognitive impairment and heart failure is well described but our understanding of the relationship between the ...
Cannon, Jane A., McMurray, John J.V., Quinn, Terry J.   +2 more
core   +4 more sources

Dapagliflozin in Patients with Heart Failure and Reduced Ejection Fraction.

New England Journal of Medicine, 2019
BACKGROUND In patients with type 2 diabetes, inhibitors of sodium-glucose cotransporter 2 (SGLT2) reduce the risk of a first hospitalization for heart failure, possibly through glucose-independent mechanisms. More data are needed regarding the effects of
J. McMurray, S. Solomon, S. Inzucchi, L. Køber, M. Kosiborod, F. Martinez, P. Ponikowski, M. Sabatine, I. Anand, J. Bělohlávek, M. Böhm, C. Chiang, V. Chopra, Rudolf A. de Boer, Akshay S. Desai, M. Diez, J. Drożdż, A. Dukát, J. Ge, J. Howlett, T. Katova, M. Kitakaze, C. Ljungman, B. Merkely, J. Nicolau, E. O’Meara, M. Petrie, P. N. Vinh, M. Schou, S. Tereshchenko, S. Verma, C. Held, D. DeMets, K. Docherty, P. Jhund, O. Bengtsson, M. Sjöstrand, A. Langkilde, Modele O Ogunniyi   +38 more
semanticscholar   +1 more source