Results 41 to 50 of about 191,064 (352)

Sex differences and atrial fibrillation in heart failure with reduced versus preserved ejection fraction [PDF]

, 2021
Heart failure is a major public health problem. Patients with heart failure often experience dyspnoea, fatigue and/or have peripheral oedema. The prognosis of heart failure remains poor, with a severely impaired quality of life, frequent hospitalizations
Santema, Bernadet
core   +1 more source

Ribose supplementation alone or with elevated creatine does not preserve high energy nucleotides or cardiac function in the failing mouse heart [PDF]

, 2013
Background: Reduced levels of creatine and total adenine nucleotides (sum of ATP, ADP and AMP) are hallmarks of chronic heart failure and restoring these pools is predicted to be beneficial by maintaining the diseased heart in a more favourable energy ...
Aksentijevic, Dunja, Faller, Kiterie M.E., Lygate, Craig A., Medway, Debra J., Neubauer, Stefan, Schneider, Jürgen E., Sebag-Montefiore, Liam   +6 more
core   +8 more sources

Axial Muscle Size as a Strong Predictor of Death in Subjects With and Without Heart Failure

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background The impact of skeletal muscle size, quantified using simple noninvasive images routinely obtained during cardiac magnetic resonance imaging studies on mortality in the heart failure (HF) population is currently unknown.
Anupam Kumar, Bilal A. Ansari, Jessica Kim, Arpita Suri, Sowmya Gaddam, Sowjanya Yenigalla, Jagan M. Vanjarapu, Senthil Selvaraj, Dheera Tamvada, Jonathan Lee, Scott R. Akers, Julio A. Chirinos   +11 more
doaj   +1 more source

Cardiac metabolism — A promising therapeutic target for heart failure [PDF]

, 2017
Both heart failure with reduced ejection fraction (HFrEF) and with preserved ejection fraction (HFpEF) are associated with high morbidity and mortality.
Frenneaux, Michael P, Loudon, Brodie L, Madhani, Melanie, Noordali, Hannah   +3 more
core   +2 more sources

Predicting Heart Failure With Preserved and Reduced Ejection Fraction [PDF]

Circulation: Heart Failure, 2016
Background— Heart failure (HF) is a prevalent and deadly disease, and preventive strategies focused on at-risk individuals are needed. Current HF prediction models have not examined HF subtypes. We sought to develop and validate risk prediction models for HF with preserved and reduced ejection fraction (HFpEF, HFrEF).
Ho, Jennifer E., Enserro, Danielle, Brouwers, Frank P., Kizer, Jorge R., Shah, Sanjiv J., Psaty, Bruce M., Bartz, Traci M., Santhanakrishnan, Rajalakshmi, Lee, Douglas S., Chan, Cheeling, Liu, Kiang, Blaha, Michael J., Hillege, Hans L., van der Harst, Pim, van Gilst, Wiek H., Kop, Willem J., Gansevoort, Ron T., Vasan, Ramachandran S., Gardin, Julius M., Levy, Daniel, Gottdiener, John S., de Boer, Rudolf A., Larson, Martin G.   +22 more
openaire   +3 more sources

Vericiguat: The Fifth Harmony of Heart Failure with Reduced Ejection Fraction

Journal of Cardiovascular Development and Disease, 2023
Heart failure with reduced ejection fraction is a chronic and progressive syndrome that continues to be a substantial financial burden for health systems in Western countries. Despite remarkable advances in pharmacologic and device-based therapy over the
Luigi Falco, Benedetta Brescia, Dario Catapano, Maria Luigia Martucci, Fabio Valente, Rita Gravino, Carla Contaldi, Giuseppe Pacileo, Daniele Masarone   +8 more
doaj   +1 more source

Spironolactone for heart failure with preserved ejection fraction [PDF]

, 2014
BACKGROUND: Mineralocorticoid-receptor antagonists improve the prognosis for patients with heart failure and a reduced left ventricular ejection fraction.
Anand, Inder S., Assmann, Susan F., Boineau, Robin, Claggett, Brian, Clausell, Nadine, Desai, Akshay S., Diaz, Rafael, Fleg, Jerome L., Gordeev, Ivan, Harty, Brian, Heitner, John F., Kenwood, Christopher T., Lewis, Eldrin F., McKinlay, Sonja M., O'Meara, Eileen, Pfeffer, Marc A., Pitt, Bertram, Probstfield, Jeffrey L., Shaburishvili, Tamaz, Shah, Sanjiv J., Solomon, Scott D., Sweitzer, Nancy K., TOPCAT Investigators, Ventura, H., Yang, Song   +24 more
core   +1 more source

Sacubitril and valsartan fixed combination to reduce heart failure events in post-acute myocardial infarction patients [PDF]

, 2017
Heart failure is a term used to define a constellation of symptoms and signs that are commonly attributed to the inability of the heart to produce a cardiac output that meets the demands of the body. It remains a deadly disease, affecting between 1-2% of
Lang, C. C., Zaid Iskandar, M.
core   +2 more sources

Improved cardiac and venous pressures during hospital stay in patients with acute heart failure: an echocardiography and biomarkers study

ESC Heart Failure, 2020
Aims Changes in echocardiographic parameters and biomarkers of cardiac and venous pressures or estimated plasma volume during hospitalization associated with decongestive treatments in acute heart failure (AHF) patients with either preserved left ...
Eiichi Akiyama, Raphaël Cinotti, Kamilė Čerlinskaitė, Lucas N.L. Van Aelst, Mattia Arrigo, Rui Placido, Tahar Chouihed, Nicolas Girerd, Faiez Zannad, Patrick Rossignol, Marc Badoz, Jean‐Marie Launay, Etienne Gayat, Alain Cohen‐Solal, Carolyn S.P. Lam, Jeffrey Testani, Wilfried Mullens, Gad Cotter, Marie‐France Seronde, Alexandre Mebazaa   +19 more
doaj   +1 more source

Autonomic regulation therapy to enhance myocardial function in heart failure patients: the ANTHEM-HFpEF study. [PDF]

, 2017
BackgroundApproximately half of the patients presenting with new-onset heart failure (HF) have HF with preserved left ventricular ejection fraction (HFpEF) and HF with mid-range left ventricular ejection fraction (HFmrEF).
Amurthur, Badri, Anand, Inder S, Ardell, Jeffrey L, DiCarlo, Lorenzo A, KenKnight, Bruce H, Kumar, H Uday, Libbus, Imad, Mittal, Sanjay, Premchand, Rajendra K   +8 more
core   +1 more source