Results 81 to 90 of about 66,290,039 (265)

Real-world insights into empagliflozin use in heart failure across ejection fractions and patients with or without diabetes: a multicenter study from Bangladesh

BMC Endocrine Disorders
Background Empagliflozin, a member of the Sodium-Glucose Co-Transporter 2 (SGLT-2) inhibitor family, is a promising antidiabetic drug with proven benefits in heart failure (HF). However, its effects in heart failure patients in varying ejection fractions
Shahjada Selim, Md. Fakhrul Islam Khaled, Dipal Krishna Adhikary, Mir Jamal Uddin, Abdul Wadud Chowdhury, Saidur Rahman Khan, A. K. M. Monwarul Islam, Kazi Nazrul Islam, Sujoy Kumar Saha, Chayan Kumar Singha, Md. Abu Bakar Siddique, Chinmoy Saha, Suraiya Rahman Shova, Khondoker Md. Ferdoush Siraj, Syed E. Shaude, Sajal Krishna Banerjee   +15 more
doaj   +1 more source

Hypophosphatemia\ua0is common after intravenous ferric carboxymaltose infusion among patients with symptomatic heart failure with reduced ejection fraction

, 2020
Administration of intravenous ferric carboxymaltose (FCM) for iron-deficient patients suffering heart failure with reduced ejection fraction (HFrEF) has been associated with transient hypophosphatemia.
Hay, Karen, Yee Weng Wong, Laher, Shaaheen, Alexander Dashwood, Fiona Chui, Shaaheen Laher, Vale, Cassandra, Chui, Fiona, Karen Hay, Wong, Yee Weng, Dashwood, Alexander, Cassandra Vale   +11 more
core   +1 more source

Review of Gastrointestinal Capsule Robots: Materials, Actuation, Diagnostics, and Therapeutics

Advanced Science, EarlyView.
This review examines gastrointestinal capsule robots through a systems engineering lens, covering shell materials, actuation and localization strategies, diagnostic modalities, therapeutic interventions, and commercialization status. By mapping the complete technological chain from fabrication to clinical deployment, this work identifies critical gaps ...
Zengsheng Li, Zhongguo Ren, Yiliang Lin, Xianfeng Xia, Tianlong Li, Kai Fung Chan, Philip Wai Yan Chiu, Wei Peng Yong, Mengmeng Sun   +8 more
wiley   +1 more source

Prevalence of stage B heart failure in patients undergoing echocardiography during regular clinical practice

Indian Heart Journal
Recognizing individuals with stage B heart failure (HF) is important to prevent or delay its progression to symptomatic HF. Unfortunately, no study at present describes the prevalence of stage B HF in Indian patients.
Rakesh Gupta, Tamoghna Das, Malvika K. Suchak, Smita Suraj Kudalkar, Prasenjit Pandey, Sameer Shrivastava, Manish Bansal, M.K. Das   +7 more
doaj   +1 more source

Prognostic Significance of Resting Heart Rate and Use of beta-Blockers in Atrial Fibrillation and Sinus Rhythm in Patients With Heart Failure and Reduced Ejection Fraction: Findings From the Swedish Heart Failure Registry

, 2015
BACKGROUND: In heart failure and reduced ejection fraction, the prognostic role of heart rate (HR) in atrial fibrillation (AF) is unknown and the effectiveness of beta-blockers has recently been questioned in AF.
Petzold, Max, Adiels, Martin,, Petzold, Max,, Sartipy, U., Adiels, Martin, Fu, Michael,, Lund, L. H., Fu, Michael, Dahlstrom, U., Li, S. J., Li, Shi-Jun,, Lund, Lars H.,, Dahlström, Ulf,, Sartipy, Ulrik,   +13 more
core   +1 more source

A Novel Pak1 Activator Ameliorates ER Stress for HFpEF Therapy

Advanced Science, EarlyView.
Chronic metabolic stress is a major contributor to HFpEF progression. Under prolonged metabolic stress, Pak1 activity becomes impaired, contributing to disrupted ER proteostasis, cardiomyocyte apoptosis, fibrosis, and diastolic dysfunction. Mechanistically, Pak1 overexpression activates the ERK1/2–MNK1–eIF4E signaling axis, promotes translational ...
Honglin Xu, Hongyuan Zhang, Tayyiba Azam, Susanne S. Hille, Yingjuan Liu, Min Zi, Jiaqing Lang, He Yu, Yujia Cao, Bernard D. Keavney, Tamer M. A. Mohamed, Jessica M. Miller, Riham R. E. Abouleisa, Ming Xu, Elizabeth J. Cartwright, Oliver J. Müller, Ming Lei, Xin Wang   +17 more
wiley   +1 more source

Efficacy of Dapagliflozin in Black Versus White Patients With Heart Failure and Reduced Ejection Fraction

, 2022
Objectives: This study sought to investigate the efficacy and safety of dapagliflozin in Black and White patients with heart failure (HF) with reduced ejection fraction (HFrEF) enrolled in DAPA-HF (Study to Evaluate the Effect of Dapagliflozin on the ...
Howlett, Jonathan G., Lindholm, Daniel, Anand, Inder S., O'Meara, Eileen, O’Meara, Eileen, Solomon, Scott D., Kosiborod, Mikhail N., Sabatine, Marc S., Docherty, Kieran F., Nicolau, Jose C., Inzucchi, Silvio E., Diez, Mirta, Køber, Lars, Bengtsson, Olof, Langkilde, Anna Maria, Martinez, Felipe A., McMurray, John J.V., Ogunniyi, Modele O., Sjöstrand, Mikaela, Ponikowski, Piotr, McMurray, John J. V., Kober, Lars, Desai, Akshay S., Verma, Subodh, Jhund, Pardeep S.   +24 more
core   +1 more source

Programmable Paracrine‐Mimetic Microneedle System for Temporal Regulation of Cardiac Repair

Advanced Science, EarlyView.
Temporal signaling is encoded into a programmable paracrine‐mimetic microneedle patch via tris(2,2'‐bipyridyl)dichlororuthenium(II) hexahydrate/sodium persulfate‐tuned hydrogel microparticles that deliver TGF‐β, IGF‐1, and VEGF over phase‐matched 7‐, 14‐, and 28‐day windows.
Yichen Dai, Pengchong Du, Zhaoyang Wang, Surilige, Rangga Fokta, Renjian Tan, Xiqing Zhao, Shuoyi Zhang, Yuecheng Wang, Yixin Zhang, Ziliang Fu, Rui Gong, Cheng Jiang, Yisheng He, Qiguang Wang, Renke Li, Khoon Lim, Junnan Tang, Xiaolin Cui   +18 more
wiley   +1 more source

A biomarker guided approach in heart failure [PDF]

, 2014
Heart failure is one of the commonest diagnoses presenting to physicians in the community or hospital care. Symptoms are often subjective, with clinicians having to rely on clinical assessment and radiological imaging to manage these patients.
Abela, Mark
core  

Self‐Powered All‐in‐One Wearable Bioelectronics Driven by Pneumatic Energy Buffering of Daily Footsteps

Advanced Science, EarlyView.
A pneumatic energy‐buffering strategy transforms transient and intermittent footsteps into quasi‐continuous electrical energy for a self‐powered wearable biosensing platform. The footwear‐integrated air‐pumping harvester, combined with the rationally designed power‐management system, powers a wearable ankle PPG device with reduced motion artifacts ...
Ji‐Seok Kim, Tae Woog Kang, Hyunjoon Yoo, Jawon Ha, Yunuo Huang, Hee Han, Chi Won Ahn, Woon‐Hong Yeo, Il‐Kwon Oh   +8 more
wiley   +1 more source