Results 191 to 200 of about 6,649,603 (308)

Synchronized Imaging of Hydrogen Peroxide and Hydroxyl Radical in Pyroptosis and Epilepsy

open access: yesAdvanced Science, EarlyView.
A dual‐responsive fluorescent probe, HH, enables synchronized visualization of H2O2 and •OH through spectrally resolved green and red channels. By tracking redox dynamics in pyroptosis and epilepsy models, HH reveals ROS elevation during seizure‐like pathology and supports evaluation of antioxidant and antiepileptic therapeutic interventions.
Yabing Gan   +9 more
wiley   +1 more source

Black Hole Quencher‐Enhanced Plasmonic Photothermal Conversion

open access: yesAdvanced Science, EarlyView.
Researchers have developed a universal method to boost plasmonic photothermal conversion by attaching black hole quencher (BHQ) molecules to matched metal nanostructures. This hybrid approach increases efficiency by roughly threefold, reaching up to 69.1% in the near‐infrared‐II window.
Ruiyuan Zhang   +3 more
wiley   +1 more source

Heart Rate, Blood Pressure, Percent Leg Volume Change, LBNP

open access: yes
Graphs reflecting biomedical data for Heart Rate, Blood Pressure, Percent Leg Volume Change, and ...

core  

Engineering Synergistic Intra‐/Intermolecular Conformational Locking via Side‐Chain Branching: A β‐Sheet‐Inspired Strategy for Planar NIR‐II Phototheranostic Aggregates

open access: yesAdvanced Science, EarlyView.
A bio‐inspired side‐chain branching strategy is developed to orchestrate a dual noncovalent conformational locking (NoCL) network, enabling the construction of perfectly planar NIR‐II phototheranostic aggregates. Such structural precision maximizes light‐harvesting efficiency and optimizes exciton dynamics, ensuring synchronized enhancements in NIR‐II ...
Cheng Lu   +11 more
wiley   +1 more source

Programmable Encapsulation Enables On‐Demand Proliferation of Therapeutic Bacteria for Potent Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
A programmable encapsulation technology is developed to reduce bacterial immunogenicity and proliferation after systemic administration. The cross‐linked polymer networks around individual bacteria enable immunogenic shielding and permit selective proliferation in tumors, allowing the bacteria to convert tumor‐accumulated ammonia into L‐arginine and ...
Jianhui Yang   +12 more
wiley   +1 more source

The IRE1‐XBP1s Axis Drives Inflammatory Osteolysis by Regulating a 5‐HT Dependent Endogenous Anti‐Autophagy Mechanism

open access: yesAdvanced Science, EarlyView.
A previously unrecognized IRE1‐XBP1s‐Slc6a4 signaling axis links endoplasmic reticulum stress to serotonin metabolism, autophagy, and inflammatory osteoclastogenesis. By promoting intracellular serotonin uptake and reducing endogenous 3‐methyladenine accumulation, this pathway accelerates inflammatory bone destruction and provides a promising ...
Pengchao Yang   +14 more
wiley   +1 more source

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