Results 51 to 60 of about 916,312 (327)

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

FEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao, Qiangbing Yang, Christian J.B. Snijders Blok, Mark A. Daniels, Pieter A. Doevendans, Raymond Schiffelers, Joost P.G. Sluijter, Zhiyong Lei   +7 more
wiley   +1 more source

Sinusoidal fetal heart rate pattern [PDF]

, 2016
We describe 2 cases of term anemic fetuses with different sinusoidal pattern morphology, and possible mechanisms.nbspCasesmdashThe first patient noted sudden cessation of fetal movement on the day of presentation. She had a sinusoidal FHR pattern.
Ikeda, T. (Tomoaki), Katsuragi, S. (Shinji), Parer, J. T. (Julian)   +2 more
core  

Novel hybrid extraction systems for fetal heart rate variability monitoring based on non-invasive fetal electrocardiogram [PDF]

, 2019
This study focuses on the design, implementation and subsequent verification of a new type of hybrid extraction system for noninvasive fetal electrocardiogram (NI-fECG) processing.
Jaroš, René, Kahánková, Radana, Koziorek, Jiří, Martinek, Radek   +3 more
core   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source

Passive fetal heart rate monitoring apparatus and method with enhanced fetal heart beat discrimination [PDF]

, 1996
An apparatus for acquiring signals emitted by a fetus, identifying fetal heart beats and determining a fetal heart rate. Multiple sensor signals are outputted by a passive fetal heart rate monitoring sensor.
Livingston, David L., Pretlow, III, Robert A., Zahorian, Stephen A.   +2 more
core   +1 more source

Amélioration de l'estimation du rythme cardiaque foetal en utilisant les signaux Doppler directionnels et YIN [PDF]

, 2012
National audienceTechniques dedicated to the fetal heart rate detection identify the patterns that repeat themselves over the time. The heart rate estimation is algorithmically similar to the estimation of the fundamental frequency (pitch) of voice ...
Girault, Jean-Marc, Ménigot, Sébastien, Voicu, Iulian   +2 more
core   +3 more sources

Loss of primary cilia promotes EphA2‐mediated endothelial‐to‐mesenchymal transition in the ovarian tumor microenvironment

Molecular Oncology, EarlyView.
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho, Yubin Hah, Eunsik Yun, Hye In Ka, Aram Lee, Sora Han, Dawn Lee, Sung Wook Kim, Jong Hoon Park, Byung Su Kwon, Young Yang, Jongmin Kim   +11 more
wiley   +1 more source

Perceptions and experiences of skilled birth attendants on using a newly developed strap-on electronic fetal heart rate monitor in Tanzania

BMC Pregnancy and Childbirth, 2019
Background Regular fetal heart rate monitoring during labor can drastically reduce fresh stillbirths and neonatal mortality through early detection and management of fetal distress. Fetal monitoring in low-resource settings is often inadequate.
Sara Rivenes Lafontan, Hussein L. Kidanto, Hege L. Ersdal, Columba K. Mbekenga, Johanne Sundby   +4 more
doaj   +1 more source

Mathematical tools for identifying the fetal response to physical exercise during pregnancy [PDF]

, 2008
In the applied mathematics literature there exist a significant number of tools that can reveal the interaction between mother and fetus during rest and also during and after exercise.
Barakat Carballo, Ruben, Stirling, James, Zakynthinaki, María S.   +2 more
core   +2 more sources

Comparison of diurnal variations, gestational age and gender related differences in fetal heart rate (FHR) parameters between appropriate-for-gestational-age (AGA) and small-for-gestational-age (SGA) fetuses in the home environment [PDF]

, 2018
Objective To assess the influence of gender, time of the day and gestational age on fetal heart rate (FHR) parameters between appropriate-for-gestational-age (AGA) and small-for-gestational age (SGA) fetuses using a portable fetal ECG monitor employed ...
A Adan, A Nawathe, A Nensi, AA Baschat, AJ Ditisheim, C Amorim-Costa, C Amorim-Costa, C Amorim-Costa, Dilly Anumba, E Ozkaya, E Soncini, EM Graatsma, F Figueras, F Marzbanrad, G Seliger, GH Visser, H K, H Kapaya, Habiba Kapaya, J Pardey, J Piazze, JG Stinstra, JI de Vries, JY Kwon, LA Fleisher, LM Nardozza, M Muro, MA Hasan, Martin Gerbert Frasch, P Burton, R Babazadeh, R Sameni, Richard Jacques, RM Grivell, RM Grivell, S Lange, S Lunshof, SV Koenen, T Stampalija, T Yanagihara, V Serra, WR Cohen   +41 more
core   +3 more sources