The use of decellularized xenogeneic heart valves might offer a solution to overcome the issue of human valve shortage. The aim of this study was to revise decellularization protocols in combination with enzymatic deglycosylation, in order to reduce the ...
K. Findeisen+9 more
semanticscholar +1 more source
Bridging aortic valve surgery to 21st century. what can a surgeon do [PDF]
Aortic valve stenosis is the most clinically relevant valvular heart disease in the elderlies. Surgical aortic valve replacement (SAVR) represented, for decades, the standard of care for the treatment of severe aortic stenosis.
Barretta, Antonio+13 more
core +1 more source
Guided Tissue Regeneration in Heart Valve Replacement: From Preclinical Research to First-in-Human Trials [PDF]
Heart valve tissue-guided regeneration aims to offer a functional and viable alternative to current prosthetic replacements. Not requiring previous cell seeding and conditioning in bioreactors, such exceptional tissue engineering approach is a very ...
Gerosa, Gino, Iop, Laura
core +4 more sources
Remote Ischemic Preconditioning Neither Improves Survival nor Reduces Myocardial or Kidney Injury in Patients Undergoing Transcatheter Aortic Valve Implantation (TAVI) [PDF]
BACKGROUND: Peri-interventional myocardial injury occurs frequently during transcatheter aortic valve implantation (TAVI). We assessed the effect of remote ischemic preconditioning (RIPC) on myocardial injury, acute kidney injury (AKIN) and 6-month ...
Flechsig, Mandy+14 more
core +1 more source
Anticoagulation During Pregnancy with a Mechanical Pulmonary Valve: Patient and Medical Perspective
This article discusses the challenges of supporting a successful pregnancy in a woman with multiple prosthetic heart valves and a complicated cardiac history, from both the patient and provider perspective.
Lauren Ledingham+2 more
doaj +1 more source
Long-term survival after aortic valve replacement with the Mitroflow bioprosthesis : a comparative study [PDF]
Background Recent case reports of early structural degeneration of the Mitroflow valve have cast doubts on the suitability of this bioprosthesis, particularly in the smaller sizes, and in younger patients.
Camilleri, Liberato, Manche, Alexander
core +1 more source
Controlled Comparison of Simulated Hemodynamics across Tricuspid and Bicuspid Aortic Valves [PDF]
Bicuspid aortic valve is the most common congenital heart defect, affecting 1-2% of the global population. Patients with bicuspid valves frequently develop dilation and aneurysms of the ascending aorta. Both hemodynamic and genetic factors are believed to contribute to dilation, yet the precise mechanism underlying this progression remains under debate.
arxiv +1 more source
Surgical techniques for aortic valve xenotransplantation
Background Heart valve replacement in neonates and infants is one of the remaining unsolved problems in cardiac surgery because conventional valve prostheses do not grow with the children.
Jennie H. Kwon+6 more
doaj +1 more source
Infection in prosthetic material [PDF]
Surgical site infection (SSI) occurs when a wound created as part of a surgical procedure becomes infected. SSI is one of the most common healthcare-associated infections and occurs in approximately 5% of patients undergoing a surgical procedure. SSI may
Chetter, Ian, Smith, George
core +1 more source
Comparison of Immersed Boundary Simulations of Heart Valve Hemodynamics against In Vitro 4D Flow MRI Data [PDF]
The immersed boundary (IB) method is a mathematical framework for fluid-structure interaction problems (FSI) that was originally developed to simulate flows around heart valves. Direct comparison of FSI simulations around heart valves against experimental data is challenging, however, due to the difficulty of performing robust and effective simulations,
arxiv +1 more source