Results 161 to 170 of about 80,799 (293)

Metabolic alterations in human pulmonary artery smooth muscle cells treated with PDGF‐BB

Animal Models and Experimental Medicine, EarlyView.
Metabolic abnormalities are considered to play a key regulatory role in vascular remodeling of pulmonary arterial hypertension. We analyzed the metabolome in the culture supernatants of human pulmonary artery smooth muscle cells (PASMC) during the malignant proliferation phenotype transition via a targeted metabolomics method. Significant and extensive
Meng‐Jie Zhang, Jie‐Jian Kou, Hong‐Da Zhang, Xin‐Mei Xie, Yun‐Feng Zhou, Ping Yuan, Xiao‐Bin Pang, Lu‐Ling Zhao, Jing Qiu, Yang‐Yang He   +9 more
wiley   +1 more source

Rapid severe hypertension and organ damage in two‐kidney two‐clip rats produced by different sizes of clips

Animal Models and Experimental Medicine, EarlyView.
Blood pressure increases immediately when the 2K2C rats (made with 0.3, 0.25, and 0.2 mm U‐shaped clips) regain consciousness from anesthesia. 100% of the rats develop hypertension on the day of 2K2C surgery. Blood pressure continues to rise, resulting in severe hypertension and organ damage to the brain, heart, aorta, and kidneys at 1, 2, 4, and 6 ...
Jia‐Sheng Tian, Qi‐Sheng Ling, Yu‐Chen Wei, Dao‐Xin Wang, Chao‐Yu Miao   +4 more
wiley   +1 more source

Animal models of lung cancer: Phenotypic comparison of different animal models of lung cancer and their application in the study of mechanisms

Animal Models and Experimental Medicine, EarlyView.
Grafts used to construct lung cancer animal models come from various sources, primarily cell lines, patient‐derived tumor tissues, and circulating tumor cells. Based on the sources of grafts and research objectives, lung cancer animal models can be categorized into several types: chemical‐induced models, orthotopic transplantation models, heterotopic ...
Zixuan Yang, Xianbin Zhao, Lili Tan, Pingxinyi Que, Tong Zhao, Wei Huang, Dejiao Yao, Songqi Tang   +7 more
wiley   +1 more source

Biventricular electromechanical dysfunction and molecular remodeling in a rat model of advanced pulmonary arterial hypertension. [PDF]

J Transl Med
Lo Muzio FP, Caputo A, Statello R, Hu M, Maestri R, Pelà G, Cabassi A, Burattini M, Rozzi G, Berrettoni S, Montanini B, Rossi S, Fassina L, Luciani GB, Condorelli G, Miragoli M.   +15 more
europepmc   +1 more source

Improved early ventricular performance with a right ventricle to pulmonary artery conduit in stage 1 palliation for hypoplastic left heart syndrome: evidence from strain Doppler echocardiography [PDF]

, 2004
Marina Hughes
openalex   +1 more source

Toward developing a compact total artificial heart using a soft robotic fluidic transmission system. [PDF]

Sci Adv
Arfaee M, van Laake LC, Zou S, Bording C, Kluin J, Overvelde JTB.   +5 more
europepmc   +1 more source

Protective effects of allicin against stanozolol‐induced cardiotoxicity: Physiological and histopathological evidence in a rabbit model

Animal Models and Experimental Medicine, EarlyView.
There are many forms of anabolic steroids, including stanzolo (Winstrol), which are popular for their muscle‐building effects but dangerous to the heart. This present work is aimed at evaluating the pharmacological impact of allacin, a natural attribute obtained from garlic on obstructing cardiac injury in rabbits that received stanzolo.
Mohammed Hayder Asker, Noor AL‐Huda Salah AL‐Zuhairy, Wassan Mhammed Husain, Mustafa Riyadh Abdullah   +3 more
wiley   +1 more source

Multimodality cardiac imaging for pre-operative evaluation in a paediatric criss-cross heart patient: a case report. [PDF]

Eur Heart J Case Rep
Saengsin K, Woragidpoonpol S, Srisuwan T, Sittiwangkul R, Makonkawkeyoon K.   +4 more
europepmc   +1 more source

Relative Heart Ventricle Mass and Cardiac Performance in Amphibians

, 2000
Gregory J. Kluthe
openalex   +2 more sources

Establishment of a humanized SCA2 mouse model carrying a CAA disruption preventing CAG repeat expansion in pathogenic genes

Animal Models and Experimental Medicine, EarlyView.
In this study, we established a mouse model in which CAG repeats do not undergo microsatellite instability (MSI) across generations. A humanized ATXN2 cDNA with four CAA interruptions within 73 CAG expansions was inserted into the Rosa26 locus of C57BL/6J mice. At the same time, a 23 CAG control mouse model was also generated.
Yao Zhang, Yufei Li, Lin Zhang, Zhaoqing Li, Keqin Lin, Kai Huang, Zhaoqing Yang, Shaohui Ma, Hao Sun, Xiaochao Zhang   +9 more
wiley   +1 more source