Results 61 to 70 of about 2,331,622 (397)

Development of a Personalized Visualization and Analysis Tool to Improve Clinical Care in Complex Multisystem Diseases With Application to Scleroderma

Arthritis Care &Research, EarlyView.
Objective In complex diseases, it is challenging to assess a patient's disease state, trajectory, treatment exposures, and risk of multiple outcomes simultaneously, efficiently, and at the point of care. Methods We developed an interactive patient‐level data visualization and analysis tool (VAT) that automates illustration of the trajectory of a ...
Ji Soo Kim, John Scott, Lauren Fisher, Lauren N. Smith, Willie Stewart, Adrianne Woods, Rob Smithwright, Diane Koher, Parastoo Aslanbeik, Aalok B. Shah, Brad Tibbils, Samantha I. Pitts, Ayse P. Gurses, Yushi Yang, Ana‐Maria Orbai, Antony Rosen, Laura K. Hummers, Scott L. Zeger, Ami A. Shah   +18 more
wiley   +1 more source

Impact of pulmonary hypertension on biventricular functions tissue doppler echocardiographic study

Egyptian Journal of Chest Disease and Tuberculosis, 2017
Background: Pulmonary hypertension (PH) essentially involves the right heart. Also left ventricular (LV) systolic and diastolic functions may be affected.
Mohamed Mahmoud, Ibrahim M. Shalan, Haitham A. Azeem   +2 more
doaj   +1 more source

Precise Quantification of Angiogenesis in 3D Biomaterials Using in Vitro CAM Models: Enhancing 3Rs in Research and Minimizing in Vivo Dependency

Advanced Functional Materials, EarlyView.
The study develops elastin–fibrin scaffolds and evaluates angiogenesis using the chorioallantoic membrane (CAM) model. Advanced imaging with confocal microscopy and Indocyanine Green dye enables precise 3D quantification of vascular networks. Findings demonstrate superior microvessel visualization compared to micro‐CT using Microfil and Optiray 350 ...
Ece Melis Er, Martha Patricia Pérez González, Beatriz Gil Garrido, Jasmine Ho, Hae‐Won Kim, Jonathan Campbell Knowles, Jia Hua, Ferdinand Lali, Prasad Sawadkar   +8 more
wiley   +1 more source

Proteomic and metabolomic analyses of the human adult myocardium reveal ventricle-specific regulation in end-stage cardiomyopathies

Communications Biology
The left and right ventricles of the human heart are functionally and developmentally distinct such that genetic or acquired insults can cause dysfunction in one or both ventricles resulting in heart failure.
Benjamin Hunter, Mengbo Li, Benjamin L. Parker, Yen Chin Koay, Dylan J. Harney, Evangeline Pearson, Jacob Cao, Gavin T. Chen, Oneka Guneratne, Gordon K. Smyth, Mark Larance, John F. O’Sullivan, Sean Lal   +12 more
doaj   +1 more source

Electrocardiographic manifestation of cardiac repolarization dispersion [PDF]

, 2019
Alterations of repolarization heterogeneity in the heart have been established as anAlterations of repolarization heterogeneity in the heart have been established as ...
Sedova Ksenia
core  

Calcium Imparts Advanced Functionalities to Silk Hydrogels for Biofabrication and Biomedical Innovation

Advanced Functional Materials, EarlyView.
The addition of calcium ions to silk fibroin enhances the hydrogel properties and, when combined with visible light crosslinking, enables compatibility with advanced light‐based fabrication techniques. Calcium ions extend the shelf‐life of silk and facilitate the fabrication of multizonal, multilayered constructs for advanced stimuli‐responsive ...
Hien A. Tran, Anton Maraldo, Chi Cong Nguyen, Trinh Thi‐Phuong Ho, Lauryn Srethbhakdi, Habib Joukhdar, Quinn van Hilst, Syamak Farajikhah, Fariba Dehghani, Thanh Nho Do, Khoon S. Lim, Jelena Rnjak‐Kovacina   +11 more
wiley   +1 more source

How to read the equine electrocardiogram? : tips and tricks [PDF]

, 2011
C
van Loon, Gunther
core   +1 more source

Nonlinear physics of electrical wave propagation in the heart: a review [PDF]

, 2016
The beating of the heart is a synchronized contraction of muscle cells (myocytes) that are triggered by a periodic sequence of electrical waves (action potentials) originating in the sino-atrial node and propagating over the atria and the ventricles ...
Alonso Muñoz, Sergio, Baer, Markus, Echebarría Domínguez, Blas   +2 more
core   +2 more sources

A tissue-engineered scale model of the heart ventricle

Nature Biomedical Engineering, 2018
Laboratory studies of the heart use cell and tissue cultures to dissect heart function yet rely on animal models to measure pressure and volume dynamics.
L. Macqueen, L. Macqueen, S. Sheehy, S. Sheehy, Christophe O. Chantre, Christophe O. Chantre, J. Zimmerman, J. Zimmerman, F. Pasqualini, F. Pasqualini, Xujie Liu, Josue A. Goss, Josue A. Goss, Patrick H. Campbell, Patrick H. Campbell, Grant M. Gonzalez, Grant M. Gonzalez, Sung-Jin Park, Sung-Jin Park, A. Capulli, A. Capulli, John P Ferrier, John P Ferrier, T. F. Kosar, L. Mahadevan, William T. Pu, W. Pu, K. Parker, K. Parker   +28 more
semanticscholar   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source