Results 81 to 90 of about 337,577 (311)

Anti–Heat Shock Protein 70 Antibodies in Meniere's Disease [PDF]

The Laryngoscope, 2000
AbstractObjectives To determine the prevalence of anti–heat shock protein 70 (anti‐HSP70) antibodies in patients with Meniere's disease and healthy subjects and to probe the relationship between antibody status and clinical features of Meniere's disease.Study Design Prospective cohort study of consecutive consenting patients with Meniere's disease ...
S D, Rauch, D, Zurakowski, D B, Bloch, K J, Bloch   +3 more
openaire   +2 more sources

Characterization of an Injectable Poly(vinyl alcohol)‐gelatin Hydrogel for Growth Factor Delivery in an Orthopedic Application

Advanced Healthcare Materials, EarlyView.
This work introduces photo‐crosslinkable tyraminated poly(vinyl alcohol)‐gelatin (PVA‐GT) hydrogels as tunable injectable platforms for tissue engineering and growth factor delivery applications. This schematic illustrates the two developed hydrogel formulations and the experimental workflow used to evaluate their physico‐chemical properties in vitro ...
Alessia Longoni, Gretel S. Major, Sam Arnold, Samuel Tomkins, Eugenia Spessot, Scott Loeffler, Kieran Lau, Richard Tan, Jessica Harte, Roslyn Kemp, Tess Reynolds, Jelena Rnjak‐Kovacina, Gary J. Hooper, Tim B. F. Woodfield, David C. Kieser, Khoon S. Lim   +15 more
wiley   +1 more source

Identification of an exported heat shock protein 70 in Plasmodium falciparum

Parasite, 2013
Host cell remodelling is a hallmark of malaria pathogenesis. It involves protein folding, unfolding and trafficking events and thus participation of chaperones such as Hsp70s and Hsp40s is well speculated.
Grover Manish, Chaubey Shweta, Ranade Shatakshi, Tatu Utpal   +3 more
doaj   +1 more source

Neonatal feed restriction modulates circulating levels of corticosterone and expression of glucocorticoid receptor and heat shock protein 70 in aged Japanese quail exposed to acute heat stress. [PDF]

, 2011
This study aimed to determine the effect of neonatal feed restriction on plasma corticosterone concentration (CORT), hippocampal glucocorticoid receptor (GR) expression, and heat shock protein (Hsp) 70 expression in aged male Japanese quail subjected to ...
A. F., Soleimani, Abdul Rahim, Raha, Idrus, Zulkifli, Omar, Abdul Rahman   +3 more
core   +1 more source

Binding of Heat-Shock Protein 70 (hsp70) to Tubulin

Archives of Biochemistry and Biophysics, 1994
Binding of heat-shock protein (hsp70) to polymerized tubulin has been investigated by in vitro experiments. The tubulin region involved in binding to hsp70 corresponds to the carboxy-terminal residues 431-444, also involved in the association with other microtubule-associated proteins (MAPs).
Sánchez, Carlos, Padilla, Rodolfo, Paciucci, Rosanna, Zabala, Juan Carlos, Ávila, Jesús   +4 more
openaire   +3 more sources

Insulin potentiates expression of myocardial heat shock protein 70 [PDF]

European Journal of Cardio-Thoracic Surgery, 2004
Since insulin stimulates nitric oxide (NO) production and an increase in NO following heat shock is required for myocardial heat shock protein 70 (Hsp70) synthesis, we hypothesized that insulin would enhance myocardial Hsp70 synthesis by augmenting NO signaling.
Gefeng, Li, R William, Currie, Imtiaz S, Ali   +2 more
openaire   +2 more sources

Peptomer Linkers Enable Kinetic Control over Co‐Delivery of Multiple Chemotherapeutics

Advanced Healthcare Materials, EarlyView.
A key challenge in combinatorial chemotherapeutic drug delivery is independent control over release kinetics, especially with drugs of similar size and structure. Here, peptoid substitutions to proteolytically degradable peptides enabled the design of fast and slow‐releasing drug linkers.
Carolyn M. Watkins, Samuel L. Hallam, Mariah J. Austin, Adrianne M. Rosales   +3 more
wiley   +1 more source

The relationship of Heat Shock Protein-70(HSP-70) and toxoplasmosis among women with abortion

Kufa Journal for Nursing Sciences, 2012
Background: Toxoplasmosis is a wide spread disease in our society, moreover it plays an important role in causation of abortion in pregnant women. Objectives: The present study was carried out to evaluate the role of Heat Shock Protein-70 (HSP-70) in ...
Kareem Mohammed, Baqur Sultan, Salman Al-Jobouri, Hanaa Al-Sagheer   +3 more
doaj   +1 more source

Could Upregulated Hsp70 Protein Compensate for the Hsp90-Silence-Induced Cell Death in Glioma Cells? [PDF]

, 2014
The molecular chaperone heat shock protein 90 alpha (Hsp90α) has been recognized in various tumours including glioma. This pilot study using a proteomic approach analyses the downstream effects of Hsp90 inhibition using 17-allylamino-17 ...
Khan, Zarine Jamsher, Munje, Chinmay, Shervington, Amal A, Shervington, Leroy Alexander   +3 more
core   +2 more sources

Dual‐Functional Polyphosphoesters for Gene Delivery: Synergistic Effects of Guanidinium and Hydrophobic Side Chains in Degradable Polymers

Advanced Healthcare Materials, EarlyView.
This study presents guanidinium‐ and indole‐functionalized polyphosphoesters as degradable, non‐viral gene delivery vectors. Through precise tuning of charge density and hydrophobicity, these polymers form stable polyplexes with low toxicity. Remarkably, minor structural changes yield up to 200‐fold differences in transfection efficiency, highlighting ...
Markus Kötzsche, Andreas Dzierza, Jan Egger, Timo Rheinberger, Christin Weilandt, Frederik R. Wurm, Ivo Nischang, Dagmar Fischer, Kalina Peneva   +8 more
wiley   +1 more source