Results 61 to 70 of about 7,058,225 (244)

Role of heat shock protein 90 in modulating ischemia-reperfusion injury in the kidney [PDF]

, 2015
Kidney transplantation is the gold standard treatment for end-stage renal disease. Renal ischemia-reperfusion injury is an unavoidable consequence of the transplantation procedure and is responsible for delayed graft function and poorer long-term ...
O'Neill, Stephen
core   +3 more sources

Post-transcriptional regulation of the trypanosome heat shock response by a zinc finger protein. [PDF]

PLoS Pathogens, 2013
In most organisms, the heat-shock response involves increased heat-shock gene transcription. In Kinetoplastid protists, however, virtually all control of gene expression is post-transcriptional.
Dorothea Droll, Igor Minia, Abeer Fadda, Aditi Singh, Mhairi Stewart, Rafael Queiroz, Christine Clayton   +6 more
doaj   +1 more source

The role of heat shock protein 70 (Hsp70) in radiation-induced immunomodulation.

Cancer Letters, 2015
Despite enormous progress in radiation technologies (high precision image-guided irradiation, proton irradiation, heavy ion irradiation) and radiotherapeutic concepts (hypofractionated irradiation schemes), the clinical outcome of radiotherapy in locally
G. Multhoff, A. Pockley, T. Schmid, D. Schilling   +3 more
semanticscholar   +1 more source

Induction of heat shock protein 70 in failing heart.

Folia Pharmacologica Japonica, 2004
Heat shock protein (Hsp) 70s including Hsp72 and Hsp73 are suggested to play an important role in the cardioprotection against stress-induced functional damage. Myocardial tolerance against ischemia/reperfusion injury is increased when myocardial Hsp72 is accumulated after an exposure of normal animals to heat shock.
TANONAKA, Kouichi, TOGA, Wakako, TAKEO, Satoshi   +2 more
openaire   +3 more sources

Heat shock induces rapid resorption of primary cilia [PDF]

, 2012
Primary cilia are involved in important developmental and disease pathways, such as the regulation of neurogenesis and tumorigenesis. They function as sensory antennae and are essential in the regulation of key extracellular signalling systems.
Ashworth, R, Prodromou, NV, Osborn, DP, Chapple, JP, Beales, PL, Knight, MM, Thompson, CL, Cogger, KF   +7 more
core   +1 more source

Comparison between in-house competitive and commercial enzyme-linked immunosorbent assays for the detection of heat shock protein 70 in milk, blood, and saliva of dairy cows

Journal of Dairy Science
: Heat shock protein 70 (HSP70) has emerged as a potential physiological indicator of heat stress (HS), recognized for its substantial upregulation in response to increased temperatures and cellular stress.
M.R.H. Rakib, V. Messina, J.I. Gargiulo, I.N. Pathirana, N.A. Lyons, S.C. Garcia   +5 more
doaj   +1 more source

The detection and role of heat shock protein 70 in various nondisease conditions and disease conditions: a literature review

Cell stress & chaperones (Print), 2015
As an intracellular polypeptide, heat shock protein 70 (HSP70) can be exposed on the plasma membrane and/or released into the circulation. However, the role of HSP70 in various nondisease and disease conditions remains unknown.
Baoge Qu, Yiguo Jia, Yuanxun Liu, Hui Wang, Guangying Ren, Hong Wang   +5 more
semanticscholar   +1 more source

Response of circulating heat shock protein 70 and anti-heat shock protein 70 antibodies to catheter ablation of atrial fibrillation [PDF]

Journal of Translational Medicine, 2013
This pilot study investigated the association between heat shock protein 70 (HSP70) and anti-HSP70 antibodies as well as their changes and rhythm outcome after atrial fibrillation (AF) catheter ablation.We studied 67 patients with AF (59±11 years, 66% male, 66% lone AF) undergoing catheter ablation. Circulating HSP70 and anti-HSP70 antibody levels were
Kornej, Jelena, Reinhardt, Claudia, Kosiuk, Jedrzej, Arya, Arash, Hindricks, Gerhard, Adams, Volker, Husser, Daniela, Bollmann, Andreas   +7 more
openaire   +2 more sources

Heat Shock Protein 70: Roles in Multiple Sclerosis

Molecular Medicine, 2012
Heat shock proteins (HSP) have long been considered intracellular chaperones that possess housekeeping and cytoprotective functions. Consequently, HSP overexpression was proposed as a potential therapy for neurodegenerative diseases characterized by the accumulation or aggregation of abnormal proteins.
María José, Mansilla, Xavier, Montalban, Carmen, Espejo   +2 more
openaire   +2 more sources

Inhibition of Heat Shock Induction of Heat Shock Protein 70 and Enhancement of Heat Shock Protein 27 Phosphorylation by Quercetin Derivatives [PDF]

Journal of Medicinal Chemistry, 2009
Inhibitors of heat-induced heat shock protein 70 (HSP70) expression have the potential to enhance the therapeutic effectiveness of heat-induced radiosensitization of tumors. Among known small molecule inhibitors, quercetin has the advantage of being easily modified for structure-activity studies.
Rongsheng E, Wang, Jeffrey L-F, Kao, Carolyn A, Hilliard, Raj K, Pandita, Joseph L, Roti Roti, Clayton R, Hunt, John-Stephen, Taylor   +6 more
openaire   +2 more sources