Expression of heat shock protein (Hsp90) paralogues is regulated by amino acids in skeletal muscle of Atlantic salmon [PDF]
, 2013 Heat shock proteins 90 (Hsp90) have an essential role in sarcomere formation and differentiation in skeletal muscle and also act as molecular chaperones during protein folding impacting a wide range of physiological processes.
Daniel Garcia de la Serrana +7 more
core +1 more source
Respiratory Research, 2021 Background Bronchial thermoplasty regulates structural abnormalities involved in airway narrowing in asthma. In the present study we aimed to investigate the effect of bronchial thermoplasty on histopathological bronchial structures in distinct asthma ...
Eleni Papakonstantinou +9 more
doaj +1 more source
Heat Shock Protein 70 (Hsp70) as an Emerging Drug Target
Journal of Medicinal Chemistry, 2010 Heat shock protein 70 (Hsp70) is a molecular chaperone that is expressed in response to stress. In this role, Hsp70 binds to its protein substrates and stabilize them against denaturation or aggregation until conditions improve.1 In addition to its ...
Christopher G. Evans +2 more
semanticscholar +1 more source
The neuroprotective potential of heat shock protein 70 (HSP70)
Molecular Medicine Today, 1999 In response to many metabolic disturbances and injuries, including stroke, neurodegenerative disease, epilepsy and trauma, the cell mounts a stress response with induction of a variety of proteins, most notably the 70-kDa heat shock protein (HSP70). Whether stress proteins are neuroprotective has been hotly debated, as these proteins might be merely an
M A, Yenari +3 more
openaire +2 more sources
Comparative modeling and mutual docking of structurally uncharacterized heat shock protein 70 and heat shock factor-1 proteins in water buffalo [PDF]
Veterinary World, 2019 Aim: In this study, a wide range of in silico investigation of Bubalus bubalis (BB) heat shock protein 70 (HSP70) and heat shock factor-1 (HSF1) has been performed, ranging from sequence evaluation among species to homology modeling along with their ...
Ravinder Singh +7 more
doaj +1 more source
Members of the heat-shock protein 70 family promote cancer cell growth by distinct mechanisms.
Genes & Development, 2005 Whereas the stress-inducible heat-shock protein 70 (Hsp70) has gained plenty of attention as a putative target for tumor therapy, little is known about the role of other Hsp70 proteins in cancer.
M. Rohde +5 more
semanticscholar +1 more source
Effectiveness of Insulin Transferrin Selenium Supplementation to Vitrified Mice Using Hemi Straw on Zona Hardening, Expression of Heat Shock Protein 70 and Caspase 3 [PDF]
, 2016 Addition of Insulin Transferrin Selenium in vitrification medium can scavenge free radicals caused by temperatures stressors due to the freezing. Insulin Transferrin Selenium is complex protein that can stimulate cell growth, prevent cell damage due to ...
Agung Budianto Ahmad +5 more
core +1 more source
Late onset of the serological response against the 18 kDa small heat shock protein of Mycobacterium ulcerans in children [PDF]
, 2014 A previous survey for clinical cases of Buruli ulcer (BU) in the Mapé Basin of Cameroon suggested that, compared to older age groups, very young children may be less exposed to Mycobacterium ulcerans.
Miriam Bolz +46 more
core +2 more sources
Heat shock protein 70 levels in children with nephrotic syndrome
The Turkish Journal of PediatricsBackground. Idiopathic nephrotic syndrome (NS) is the most prevalent glomerular disease in children. Heat shock protein 70 (HSP70) is synthesized in response to diverse stress factors like infections and oxidative stress.
Bağdagül Aksu +3 more
doaj +1 more source
Identification of an exported heat shock protein 70 in Plasmodium falciparum
Parasite, 2013 Host cell remodelling is a hallmark of malaria pathogenesis. It involves protein folding, unfolding and trafficking events and thus participation of chaperones such as Hsp70s and Hsp40s is well speculated.
Grover Manish +3 more
doaj +1 more source