Continuous molecular monitoring using electrochemical aptamer‐based sensors enables real‐time tracking of dynamic biomarkers with transformative potential for precision medicine. Achieving clinically relevant month‐long stability remains a central challenge due to multiple degradation pathways.
Shibo Liu, Xiangling Li, Wei Ouyang
wiley +1 more source
Decoding the Crosstalk Between Heat Shock Proteins and Phytochemicals in Thyroid Nodule Regression: Mechanisms and Therapeutic Implications. [PDF]
Zhang R, Lv J.
europepmc +1 more source
Bioenergetic Materials for Tissue Regeneration: Modulating Metabolism to Promote Cellular Anabolism
Bioenergetic materials (BEMs) modulate cellular metabolism to promote tissue regeneration. Their principal mechanisms of action include metabolic substrate supplementation, metabolic enzyme modulation, organelle transfer, electrical current regulation, redox homeostasis modulation, and oxygen tension modulation.
Yuchen He +7 more
wiley +1 more source
The Role of Heat Shock Proteins in Insect Stress Response, Immunity, and Climate Adaptation. [PDF]
Banfi D +3 more
europepmc +1 more source
Cannabinoid CB1 Receptor in Nociceptors Mediates Postoperative Analgesia via ASIC3 Inhibition
CB1R and ASIC3 are co‐expressed in CGRP+ nociceptors of mouse DRG. Plantar incision triggers an upregulation of ASIC3 and activation of ASIC3+ neurons, driving mechanical allodynia. CB1R activation suppresses ASIC3 function and downstream ERK1/2 phosphorylation, thereby braking nociceptive signaling and accelerating pain resolution.
Kangtai Xu +13 more
wiley +1 more source
Evaluation of serum levels of heat shock protein 70 in patients with psoriasis in Basra, Iraq
Wafaa Taresh Adday +3 more
doaj +1 more source
Immuno-informatics voyage through molecular mimicry of Heat Shock Proteins: Potential IBD immunopathogenesis. [PDF]
Alem M +5 more
europepmc +1 more source
Thermal Shifts Dominate Single‐Gene Responses to Transcription‐Targeting Antibiotics
Thermal shifts reshape bacterial responses to transcription‐targeting antibiotics. In E. coli, temperature can dominate antibiotic‐induced genome‐wide expression, particularly outside 30°C–39°C, through changes in adenosine triphosphate (ATP), nucleoid organization, and drug‐target engagement.
Rahul Jagadeesan +5 more
wiley +1 more source
Role of heat shock proteins in renal function and adaptation to heat stress: Implications for global warming. [PDF]
Tran TTT +4 more
europepmc +1 more source

