Expression of a serine protease gene prC is up-regulated by oxidative stress in the fungus Clonostachys rosea: implications for fungal survival. [PDF]
PLoS ONE, 2010 BackgroundSoil fungi face a variety of environmental stresses such as UV light, high temperature, and heavy metals. Adaptation of gene expression through transcriptional regulation is a key mechanism in fungal response to environmental stress.
Cheng-Gang Zou +8 more
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Bacterial Infection Elicits Heat Shock Protein 72 Release from Pleural Mesothelial Cells [PDF]
, 2013 Heat shock protein 70 (HSP70) has been implicated in infection-related processes and has been found in body fluids during infection. This study aimed to determine whether pleural mesothelial cells release HSP70 in response to bacterial infection in vitro
Bielsa, S +8 more
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HSP90 inhibition without heat shock response [PDF]
Blood, 2018 In this issue of Blood, Bhatia and colleagues describe a heat shock protein 90 (HSP90) C-terminal dimerization inhibitor with mechanistic differences that distinguish it from other clinically unsuccessful N-terminal ATPase binding compounds.1 Can graveyard raiding of an old therapeutic target with a new strategy bring long awaited success?
openaire +2 more sources
Advanced Functional Materials, EarlyView.Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana +2 more
wiley +1 more source
Assessment of stress tolerance acquisition in the heat-tolerant derivative strains of Bifidobacterium animalis subsp. lactis BB-12 and Lactobacillus rhamnosus GG [PDF]
, 2017 [Aims] The purpose of this study was to investigate the heat-shock response at molecular level in Lactobacillus rhamnosus GG, Bifidobacterium animalis subsp.
Aakko, J. +3 more
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Advanced Functional Materials, EarlyView.This study presents a new hole transporting material (HTM) mechanism for self‐assembled monolayers in near‐infrared organic photodetectors. The formation of zwitterions induces a strong electric field that significantly increases the work function of HTM‐coated indium tin oxide substrates. The devices exhibit low dark current and noise, along with high
Jiyoung Shin +9 more
wiley +1 more source
Polyglutamine Expanded Huntingtin Dramatically Alters the Genome-Wide Binding of HSF1 [PDF]
, 2012 In Huntington's disease (HD), polyglutamine expansions in the huntingtin (Htt) protein cause subtle changes in cellular functions that, over-time, lead to neurodegeneration and death.
Dinesh, Deepika +7 more
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Quasi‐Static to Supersonic Energy Absorption of Nanoarchitected Tubulanes and Schwarzites
Advanced Functional Materials, EarlyView.Nanoarchitected energy‐absorptive Tubulanes exhibit record energy absorption under quasi‐static conditions and exceptional inelastic energy dissipation under 750 m s−1 ballistics impact, with high performance spanning strain rates of 12 orders of magnitude.
Peter Serles +16 more
wiley +1 more source
A model for handling cell stress
eLife, 2016 The heat shock response in yeast is regulated by the interaction between a chaperone protein and a heat shock transcription factor, and fine-tuned by phosphorylation.
Laura Le Breton, Matthias P Mayer
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Differential Response of Heat-Shock-Induced p38 MAPK and JNK Activity in PC12 Mutant and PC12 Parental Cells for Differentiation and Apoptosis [PDF]
, 2010 Among the 3 mitogen-activated protein kinases -- ERK, p38 MAPK and JNK -- JNK has been suggested to participate in apoptosis, whereas p38 MAPK is thought to be part of the differentiation response.
Hiragami, Fukumi +8 more
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