Results 61 to 70 of about 349,085 (279)

Barycentric Rational Collocation Method for Nonlinear Heat Conduction Equation

Journal of Applied Mathematics, 2022
Nonlinear heat equation solved by the barycentric rational collocation method (BRCM) is presented. Direct linearization method and Newton linearization method are presented to transform the nonlinear heat conduction equation into linear equations.
Jin Li
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Quantitative analysis of heat dissipation in a micro thermal stage for a broad temperature operation

Case Studies in Thermal Engineering
A microscale thermal stage offers precise temperature control by suppressing heat conduction. For its use in a broad range of temperatures, the temperature accuracy has been under debate as both conduction and radiation become important heat paths.
Eunju Jeong, Mikyung Lim, Jeeyoung Shin, Woosung Park   +3 more
doaj   +1 more source

Analytical Solution of Heat Conduction in a Multi-Layer Orthotropic Cylinder Subject to Periodic and Asymmetric Heat Flux

Journal of King Saud University: Engineering Sciences, 1997
The problem of heat conduction in a multi-layer two-dimensional orthotropic cylinder subject to asymmetric and periodic heat flux on the outer wall was solved analytically. The dimensional analysis of the problem revealed that the heat conduction through
Bassam A. Abu-Hijleh
doaj   +1 more source

Information filtering via biased heat conduction

, 2011
Heat conduction process has recently found its application in personalized recommendation [T. Zhou \emph{et al.}, PNAS 107, 4511 (2010)], which is of high diversity but low accuracy.
J. Bennett, J. G. Liu, Jian-Guo Liu, N. Good, Qiang Guo, Tao Zhou   +5 more
core   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Simulational Study on Dimensionality-Dependence of Heat Conduction

, 2000
Heat conduction phenomena are studied theoretically using computer simulation. The systems are crystal with nonlinear interaction, and fluid of hard-core particles.
Alder B. J., Alonso D., Casati G., Dorfman J. R., Dorfman J. R., Ernst M. H., Ford J., Hatano T., Hoover W. G., Hu B., Kubo R., Kubo R., Lebowitz J. L., Lepri S., Nosé S., O'Connor A. J., Prosen T., Rieder Z., Wainwright T. E.   +18 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source