Results 31 to 40 of about 1,170,486 (272)

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

A Best Cost of Null Controllability for the 1D Heat Equation by Strategic Zone Profile

open access: yesJournal of Mathematics, 2021
This study is the third step of a project on the null controllability of the 1D heat equation. First, we show a boundary and internal results of controllability by a new approach using a linear, continuous, and surjective operator built from the solution
Cheikh  Seck   +1 more
doaj   +1 more source

Hexagonal Grid Computation of the Derivatives of the Solution to the Heat Equation by Using Fourth-Order Accurate Two-Stage Implicit Methods

open access: yesFractal and Fractional, 2021
We give fourth-order accurate implicit methods for the computation of the first-order spatial derivatives and second-order mixed derivatives involving the time derivative of the solution of first type boundary value problem of two dimensional heat ...
Suzan Cival Buranay   +2 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Solution of the model problem of heat conduction with Bessel operator

open access: yesҚарағанды университетінің хабаршысы. Математика сериясы
In this work, a model boundary value problem for a parabolic equation with a Bessel operator was investigated. The solution to the problem under consideration is sought as a sum of thermal potentials: the double-layer and volume potentials, which ...
N.K. Gulmanov   +2 more
doaj   +1 more source

Non-stationary heat conduction in one-dimensional chains with conserved momentum

open access: yes, 2009
The Letter addresses the relationship between hyperbolic equations of heat conduction and microscopic models of dielectrics. Effects of the non-stationary heat conduction are investigated in two one-dimensional models with conserved momentum: Fermi-Pasta-
A. V. Savin   +5 more
core   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

A method for predicting interfacial freezing of a liquid flowing over a cold surface [PDF]

open access: yes, 1969
Instantaneous thickness of a frozen layer is a function of specific heat, heat of fusion, temperatures, the frozen layer thickness at equilibrium, the thermal conductivity, and heat transfer coefficient.
Savino, J. M., Siegel, R.
core   +1 more source

Vibrations and fractional vibrations of rods, plates and Fresnel pseudo-processes

open access: yes, 2011
Different initial and boundary value problems for the equation of vibrations of rods (also called Fresnel equation) are solved by exploiting the connection with Brownian motion and the heat equation. The analysis of the fractional version (of order $\nu$)
A. Lachal   +26 more
core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

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