Results 41 to 50 of about 3,924,930 (352)

Asymptotics of the heat exchange

open access: yesJournal of Functional Analysis, 2004
If \(K\subset \mathbb R^{m}\) is a compact subset, we set \(E_{K}(t) = \int_{\mathbb R^{m}\setminus K} u(x,t)\,\roman dx\), where \(u\) is the (unique) weak solution to the heat equation \(\partial_{t}u = \Delta u\) in \((\mathbb R^{m}\setminus K)\times \mathbb R_+\) with initial condition \(u(\cdot,0) = 0\) and boundary condition \(u=1\) on \(\partial
openaire   +3 more sources

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

Membrane and plastic heat exchangers performance [PDF]

open access: yesSongklanakarin Journal of Science and Technology (SJST), 2005
The performance of a membrane-based heat exchanger utilizing porous paper as the heat and moisture transfer media is presented. The measured performance is compared with a plastic film heat exchanger.
Masud Behnia   +2 more
doaj  

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

open access: yesFEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Genetic algorithm based topology optimization of heat exchanger fins used in aerospace applications

open access: yesInternational Journal of Heat and Mass Transfer, 2019
Topology Optimization (TO) in the design of structural components is commonly used and well explored. However, its usage in the design of complex thermo-fluid equipment used in aerospace applications is limited and relatively new.
Bashir S. Mekki, Joshua Langer, S. Lynch
semanticscholar   +1 more source

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

open access: yesFEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq   +3 more
wiley   +1 more source

The MMP‐9/TIMP‐1 Ratio and Concentrations of Osteopontin Are Elevated in Cerebrospinal Fluid of People With Multiple Sclerosis and Decrease After Autologous Hematopoietic Stem Cell Transplantation

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To evaluate the utility of cerebrospinal fluid (CSF) biomarkers—matrix metalloproteinase‐9 (MMP‐9), tissue inhibitor of metalloproteinases‐1 (TIMP‐1), the MMP‐9/TIMP‐1 ratio, and osteopontin (OPN)—as indicators of blood–brain barrier (BBB) integrity and disease activity in people with relapsing–remitting multiple sclerosis (pwMS ...
Ivan Pavlovic   +6 more
wiley   +1 more source

Response Surface Method for Design of Room Air Conditioner Heat Exchangers with Decreasing Tube Diameter

open access: yesZhileng xuebao, 2011
The response surface method is applied to design the heat exchanger with decreasing tube diameter, for the traditional design methods are not suitable for the optimization of the performance and cost of heat exchanger simultaneously.
Wu Zhaoguo   +5 more
doaj   +2 more sources

Analysis of Heat Exchange Rate for Low-Depth Modular Ground Heat Exchanger through Real-Scale Experiment [PDF]

open access: gold, 2021
Kwonye Kim   +5 more
openalex   +1 more source

Infrared Neural Stimulation Elicits Distinct Molecular Pathways in Astrocytes Based on Laser Pulse Parameters

open access: yesAdvanced Biology, EarlyView.
Infrared (IR) light evokes distinct calcium and water transport responses in astrocytes, depending on stimulation duration and protocol. This study uses widefield imaging and pharmacology to reveal differential engagement of astroglial signaling pathways.
Wilson R. Adams   +7 more
wiley   +1 more source

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