Results 41 to 50 of about 176,755 (335)

Germline variants in CDKN2A wild‐type melanoma prone families

open access: yesMolecular Oncology, EarlyView.
Among melanoma‐prone families, wild‐type for CDKN2A and CDK4, some have pathogenic variants in genes not usually linked to melanoma. Furthermore, rare XP‐related variants and variants in MC1R are enriched in such families. Germline pathogenic variants in CDKN2A are well established as an underlying cause of familial malignant melanoma. While pathogenic
Gjertrud T. Iversen   +5 more
wiley   +1 more source

Hidden symmetries and nonlinear constitutive relations for tight-coupling heat engines [PDF]

open access: yesNew J. Phys. 17, 045013 (2015), 2015
Typical heat engines exhibit a kind of homotypy: The heat exchanges between a cyclic heat engine and its two heat reservoirs abide by the same function type; the forward and backward flows of an autonomous heat engine also conform to the same function type.
arxiv   +1 more source

Purification and characterization of a thermophilic NAD+‐dependent lactate dehydrogenase from Moorella thermoacetica

open access: yesFEBS Open Bio, EarlyView.
The thermophilic acetogenic model organism Moorella thermoacetica can utilize lactate as substrate. The formation of lactate by reduction of pyruvate is energetically favorable, but the reverse reaction, the oxidation of lactate to pyruvate with NAD+ as electron acceptor is challenging.
Florian P. Rosenbaum, Volker Müller
wiley   +1 more source

Experimental and numerical investigation of heat transfer and flow characteristics for tractor heat exchanger (radiator)

open access: yesمجلة النهرين للعلوم الهندسية, 2017
An experimental and numerical study was carried out to investigate heat transfer and flow characteristics through the tractor heat exchanger (radiator). The engine of the tractor is Diesel (compression ignition) engine type.
Kadhim F. Nasir
doaj  

Efisiensi dan Fouling Factor Sealtube Heat Exchanger Pada Proses Pendinginan Refined Bleached Deodorized Palm Oil

open access: yesRekayasa, 2022
Refined Bleached Deodorized Palm Oil (RBDPO) is a product of the crude palm oil (CPO) refining process. RBDPO is one of Indonesia's strategic commodities for low price cooking oil production. The cooking oil processing uses a heat transfer device such as
Jabosar Ronggur Hamonangan Panjaitan   +3 more
doaj   +1 more source

Identification of inhibitors of the Salmonella FraB deglycase, a drug target

open access: yesFEBS Open Bio, EarlyView.
A high‐throughput screen was used to identify inhibitors of Salmonella FraB, a drug target. Characterization of top hits (identified after an additional counter screen) revealed that some triazolidines, thiadiazolidines, and triazolothiadiazoles are mixed‐type inhibitors of FraB.
Jamison D. Law   +6 more
wiley   +1 more source

Preliminary Design and Analysis of Regenerative Heat Exchanger

open access: yesChemical Engineering Transactions, 2016
Heat regenerators transfer heat from one gas to another, with by storage in solids. This type of heat exchanger is used primarily when heat has to be transferred between enormous amounts of gases, when the gases are dirty and liable to plug up the ...
B. Kilkovský, Z. Jegla
doaj   +1 more source

Quantification of Bore Path Uncertainty in Borehole Heat Exchanger Arrays [PDF]

open access: yesarXiv, 2021
Borehole heat exchanger arrays have become a common implement for the utilization of thermal energy in the soil. Building these facilities is expensive, especially the drilling of boreholes, into which closed-pipe heat exchangers are inserted. Therefore, cost-reducing drilling methods are common practice, which can produce inaccuracies of varying ...
arxiv  

Heat flux splitter for near-field thermal radiation [PDF]

open access: yesAppl. Phys. Lett. 107, 053109 (2015), 2015
We demonstrate the possibility to efficiently split the near-field heat flux exchanged between graphene nano-disks by tuning their doping. This result paves the way for the developement of an active control of propagation directions for heat fluxes exchanged in near-field throughout integrated nanostructures networks.
arxiv   +1 more source

A non‐fluorescent immunohistochemistry method for measuring autophagy flux using MAP1LC3/LC3 and SQSTM1 as core markers

open access: yesFEBS Open Bio, EarlyView.
We introduce an immunohistochemistry method to measure autophagy flux, highlighting the active degradation and recycling of cellular waste. This cost‐effective approach uses tissue samples to track key markers like LC3 and SQSTM1, revealing how cells maintain health or respond to diseases such as cancer. It bridges the gap between research and clinical
Shahla Shojaei   +6 more
wiley   +1 more source

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