Results 51 to 60 of about 701,963 (354)
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
Modeling and calculating the albedo and IR heat flux applied to satellite based on the geographic position of sarellite [PDF]
فصلنامه علوم و فناوری فضایی, 2019 In this paper, a precise method for calculating albedo and IR heat flux applied to a satellite is presented. For obtaining albedo heat flux applied to a satellite, a point on the earth’s surface that sun flux reflected at that point and reach to the ...
Behzad Mohasel afshari +3 more
doaj
Journal of Ophthalmology, 2019 Background: Assessment of heat exchange processes in the human body is based on temperature and heat flux measurements. Today, there is no instrument for measuring the heat flux density from the eye.
L.I. Anatychuk +5 more
doaj +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
An estimate of the surface heat fluxes transfer of the Persian Gulf with the overlying atmosphere
Journal of Radiation Research and Applied Sciences, 2015 The ocean heat exchange process is a key mechanism in climate variations over a broad time – scale. In this study, the long–term mean surface heat fluxes over the Persian Gulf have been estimated by the empirical relations using data derived from ...
A. Rezaei-Latifi, F. Hosseinibalam
doaj +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Effect of torch angle on arc properties and weld pool shape in stationary GTAW [PDF]
, 2013 In this paper, a three dimensional numerical simulation is performed on a stationary arc to study the effect of torch angle in gas tungsten arc welding (GTAW) of SS304 stainless steel.
Abid, Muhammad +4 more
core +1 more source
Solar Energy, 2010 Abstract The solarimeter presented in this work is easy to assemble. It is calibrated and its performance is validated by means of Hottel’s method ( Hottel, 1976 ). Finally, the curves obtained with this solarimeter are compared to the ones obtained with a commercial solarimeter. This device is based on the evaluation of the heat flow in a metal rod.
Sartarelli, Salvador Andrés +4 more
openaire +2 more sources
Earth's surface heat flux [PDF]
Solid Earth, 2010 We present a revised estimate of Earth's surface heat flux that is based upon a heat flow data-set with 38 347 measurements, which is 55% more than used in previous estimates.
J. H. Davies, D. R. Davies
doaj +1 more source