Results 61 to 70 of about 701,963 (354)

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

INNOVATIVE HEAT FLUX SENSOR [PDF]

open access: yesНаучно-технический вестник информационных технологий, механики и оптики, 2017
Subject of Study.We present a method for heat flux measuring with the use of polarization properties of ferroelectric ceramics. Heat flux innovative sensor is developed on the basis of the proposed method.
G. N. Lukyanov   +3 more
doaj   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Microfluidic electro‐viscoelastic manipulation of extracellular vesicles

open access: yesFEBS Open Bio, EarlyView.
The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh   +7 more
wiley   +1 more source

An analytical investigation of the physical dimensions of natural convection flow on a vertical heated plate [PDF]

open access: yes, 2010
Analytical results of the boundary layer of natural convection air flow on a vertical heated plate are presented for both isothermal and constant heat flux plates.
Alzwayi, A.S., Paul, M.C.
core  

Isotope and density profile effects on pedestal neoclassical transport

open access: yes, 2017
Cross-field neoclassical transport of heat, particles and momentum is studied in sharp density pedestals, with a focus on isotope and profile effects, using a radially global approach.
Buller, Stefan, Pusztai, Istvan
core   +1 more source

Assessment of Surface Heat Flux and Deep Fluid Degassing in Fracture‐Dominated Geothermal Zones in Taxkorgan, Xinjiang, Western China

open access: yesGeochemistry, Geophysics, Geosystems
Understanding surface heat flux is essential for evaluating geothermal system dynamics and resource potential, particularly in tectonically active but non‐volcanic regions. This study presents the first integrated assessment of surface heat flux in three
Yingchun Wang   +4 more
doaj   +1 more source

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