Results 81 to 90 of about 2,236,491 (301)
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
Does low-protein diet improve broiler performance under heat stress conditions?
Brazilian Journal of Poultry Science, 2004 Nutrition for broilers under high temperatures is extremely important for brazilian broiler chicken industry because the amounts of consumed nutrients and environmental temperature have great effects on bird performance and carcass quality.
RL Furlan +3 more
doaj +1 more source
Ocean Thermal Energy Conversion (OTEC) [PDF]
, 1977 Energy Research and Development Administration research progress in Ocean Thermal Energy Conversion (OTEC) is outlined. The development program is being focused on cost effective heat exchangers; ammonia is generally used as the heat exchange fluid ...
Lavi, A.
core +1 more source
Thermodynamic efficiency and entropy production in the climate system [PDF]
, 2009 We present an outlook on the climate system thermodynamics. First, we construct an equivalent Carnot engine with efficiency and frame the Lorenz energy cycle in a macroscale thermodynamic context.
Lucarini, Valerio
core +2 more sources
Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
Carbon-ammonia pairs for adsorption refrigeration applications : ice making, air conditioning and heat pumping [PDF]
, 2009 A thermodynamic cycle model is used to select an optimum adsorbent-refrigerant pair in respect of a chosen figure of merit that could be the cooling production (MJ m(-3)), the heating production (MJ m(-3)) or the coefficient of performance (COP).
Critoph, Robert E. +4 more
core +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Radiogenic power and geoneutrino luminosity of the Earth and other terrestrial bodies through time
, 2020 We report the Earth's rate of radiogenic heat production and (anti)neutrino luminosity from geologically relevant short-lived radionuclides (SLR) and long-lived radionuclides (LLR) using decay constants from the geological community, updated nuclear ...
Enomoto S. +6 more
core +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source