Results 91 to 100 of about 8,455,902 (295)

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

Molecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan, Beatriz Martín‐Gracia, Eva Bassols‐Citores, Krizia Sagini, Maria K. Andersen, Tuula A. Nyman, May‐Britt Tessem, Morten B. Rye, Alicia Llorente   +8 more
wiley   +1 more source

Impact of ventilated tunnels on smoke peculiarities in train carriage fires with multiple lateral openings

Case Studies in Thermal Engineering
This research investigates the dynamics of smoke dispersion in a subway train carriage with multiple lateral openings within a ventilated subway tunnel.
Zhenkun Wu, Min Peng, Yuelei Pan, Yifan Zhu, Wenxuan Miao, Ding Li, Dongzi Qin, Panwen Ma, Guoqing Zhu   +8 more
doaj   +1 more source

Prediction of heat release rate of shredded paper tapes based on profile burning surface

, 2017
A series of shredded paper fire experiments were conducted by means of a calorimeter. The mass loss rate and heat release rate were measured. The flame spread process was recorded, which shows that the flame spread process can be divided into four ...
Wang, Jian, Mingyi Chen, Liu, Jiahao, Yaping He, Chen, Mingyi, Chao Ding, Jiang, Wei, Yao, Wei, Ma, Pingchuan, Ding, Chao, Wei Yao, Wei Jiang, Jiahao Liu, Xiao Lin, Jian Wang, Pingchuan Ma, He, Yaping (R11091), Lin, Xiao   +17 more
core   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Effects of wind speed, spacing distance and heat release rate on the combustion and flame merging characteristics of two extra-thin line fires

Case Studies in Thermal Engineering
This paper investigated the mutual interaction between two extra-thin line fires under different wind speeds of 0.4, 0.6, 0.8, 1.0 and 1.2 m/s by using a small-scale wind tunnel. The experiments involved the spacing distances of 5, 10, 15, 20, 25, 30, 35
Xinjie Huang, Hailong Ding, Xinyi Zhang, Xinyi Li, Miaomiao Wang, Pengyuan Zhang   +5 more
doaj   +1 more source

Heat release rate measurement in turbulent flames

, 2005
The dominant industrial approach for the reduction of NO x emissions in industrial gas turbines is the lean pre-mixed prevaporized concept. The main advantage of this concept is the lean operation of the combustion process; this decreases the heat ...
Ayoola, BO, Balachandran, R, Kaminski, CF, Mastorakos, E, ,   +4 more
core  

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

Molecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau, Daniel Pincher, Clifford Young, Nicholas Chappell, Noor A. Lokman, Parul Mittal, Leigh Donnellan, Martin K. Oehler, Doug A. Brooks, Peter Hoffmann   +9 more
wiley   +1 more source

Methods for predicting and implementing continuous pyrolysis rate and heat release rate of Finnish pine

Accurately determining the pyrolysis rate and heat release rate throughout the entire pyrolysis process of lignocellulosic biomass remains challenging for current methods.
Kong, Depeng, Sharma, Rajnish N., Chen, Fanbao, Zhu, Guoqing   +3 more
core   +2 more sources

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

Molecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi, Sang‐Hyeon Yoo, Ki‐Jong Rhee   +2 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source