Results 81 to 90 of about 8,455,902 (295)

A Monte Carlo analysis of the effect of heat release rate uncertainty on available safe egress time

, 2013
Available safe egress time is an important criterion to determine occupant safety in performance-based fire protection design of buildings. There are many factors affecting the calculation of available safe egress time, such as heat release rate, smoke ...
Kong, Depeng,, Kong, Depeng, Lu, Shouxiang, Johansson, Nils,, Lo, Siuming, Van Hees, Patrick,, Johansson, Nils, Lund University., Van Hees, Patrick   +8 more
core   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Combustion of forest litters under slope conditions: burning rate, heat release rate, convective and radiant fractions for different loads

, 2014
International audienceA set of experiments using a Large Scale Heat Release calorimeter was conducted to study the combustion of forest fuel beds under slope conditions. Different parameters such as the heat release rate, the mass loss rate, the geometry
Perez-Ramirez, Yolanda, Santoni, Paul Antoine, Barboni, Toussaint, Morandini, Frederic, Tihay, Virginie   +4 more
core   +1 more source

Development of a Mass- and Energy-Conserving Combustion-Capacity Model for Direct-Injection Diesel Heat Release

Energies
A reduced-order, mass- and energy-conserving combustion-capacity model was developed to represent premixed and mixing-controlled heat release in a direct-injection diesel engine.
Khalid Alkhulaifi, Jasem Alazemi, Jasem Alrajhi, Mohsen Alardhi   +3 more
doaj   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Study on the Solidification and Heat Release Characteristics of Flexible Heat Storage Filled with PCM Composite

Energies
Phase change materials (PCMs) have significant potential for utilization due to their high energy storage density and excellent safety in energy storage.
Tielei Yan, Gang Wang, Dong Zhang, Changxin Qi, Shuangshuang Zhang, Peiqing Li, Gaosheng Wei   +6 more
doaj   +1 more source

Heat release rate correlation and combustion noise in premixed flames [PDF]

, 2011
The sound emission from open turbulent flames is dictated by the two-point spatial correlation of the rate of change of the fluctuating heat release rate.
Swaminathan, N, R. BALACHANDRAN, Balachandran, R, N. SWAMINATHAN, Xu, G, G. XU, Dowling, AP, A. P. DOWLING   +7 more
core   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Heat release rate and emissions regimes of stratified pilot-ignited direct-injection natural gas combustion. [PDF]

Int J Engine Res, 2023
Rochussen J, McTaggart-Cowan G, Kirchen P.   +2 more
europepmc   +1 more source

Estimation of Rate of Heat Release by Means of Oxygen Consumption Measurements

, 2003
3 pages Provider Notes:Title: Estimation of Rate of Heat Release by Means of Oxygen Consumption Measurements; Description: Review of literature on heat of combustion of ...
NSCORT, ALS-
core