Results 11 to 20 of about 162,146 (310)

Role of heat shock protein 70 in innate alloimmunity [PDF]

Frontiers in Immunology, 2012
This article briefly describes our own experience with the proven demonstration of heat shock protein 70 in reperfused renal allografts from brain-deaddonors and reflects about its potential role as a typical damage-associated molecular pattern (DAMP) in
Walter G. eLand
doaj   +4 more sources

Heat Shock Protein 70 and Anti-heat Shock Protein 70 Antibodies in Nasal Secretions of Patients with Chronic Rhinosinusitis [PDF]

Allergy & Rhinology, 2016
Background The issue of heat shock protein (HSP) 70 and anti-HSP70 antibodies in chronic rhinosinusitis (CRS) has never been explored. Objective To determine the nasal secretion (NS) levels of HSP70 and anti-HSP70 antibodies in patients with CRS with ...
Namjil N. Tsybikov M.D., Ph.D., Elena V. Egorova M.D., Ph.D., Boris I. Kuznik M.D., Ph.D., Elena V. Fefelova M.D., Ph.D., Eli Magen M.D.   +4 more
doaj   +3 more sources

The Role of Heat Shock Protein 70 kDa in Asthma

Journal of Asthma and Allergy, 2021
Marina Shevchenko,1 Ekaterina Servuli,1,2 Zarema Albakova,1,3 Leonid Kanevskiy,1 Alexander Sapozhnikov1,3 1Department of Immunology, Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia; 2Department of ...
Shevchenko M, Servuli E, Albakova Z, Kanevskiy L, Sapozhnikov A   +4 more
doaj   +5 more sources

Circulating Heat Shock Protein 70 in Health, Aging and Disease [PDF]

BMC Immunology, 2011
Background Heat shock proteins (Hsp) are ubiquitously synthesised in virtually all species and it is hypothesised that they might have beneficial health effects.
Demanet Christian, Van Puyvelde Katrien, Onyema Oscar O, Bautmans Ivan, Njemini Rose, Mets Tony   +5 more
doaj   +4 more sources

Heat Shock Protein 70 in Alzheimer’s Disease [PDF]

BioMed Research International, 2014
Alzheimer’s disease (AD) is the most common neurodegenerative disease that caused dementia which has no effective treatment. Growing evidence has demonstrated that AD is a “protein misfolding disorder” that exhibits common features of misfolded, aggregation-prone proteins and selective cell loss in the mature nervous system.
Rui-Chun Lu, Meng-Shan Tan, Hao Wang, An-Mu Xie, Jin-Tai Yu, Lan Tan   +5 more
openaire   +2 more sources

Heat shock protein 70 and anti-heat shock protein 70 antibodies in patients with chronic glomerulonephritis [PDF]

Cell Stress and Chaperones, 2018
We evaluated the heat shock system 70 (HSP70) in patients with chronic glomerulonephritis (CGN). Seventy-six patients with CGN patients were included in our study. Ten patients with mild proteinuria (median 0.48 [0.16-0.78] g/24 h) and ten healthy subjects served as positive and negative controls, respectively.
Natalia, Chebotareva, Irina, Bobkova, Lidia, Lysenko, Natalia, Neprinzeva, Anatoly, Vinogradov, Sergey, Moiseev   +5 more
openaire   +2 more sources

The Immunosuppressive Activity of Heat Shock Protein 70 [PDF]

Autoimmune Diseases, 2012
Heat shock protein 70 (HSP70) has previously been described as a potent antitumour vaccine. The mechanism relied on the ability of tumour derived HSP70 to associate with antigenic peptides, which, when cross presented, elicited a T cell mediated antitumour response.
Pawel Stocki, Anne M. Dickinson
openaire   +3 more sources

Interaction of human heat shock protein 70 with tumor-associated peptides [PDF]

, 2009
Molecular chaperones of the heat shock protein 70 (Hsp70) family play a crucial role in the presentation of exogenous antigenic peptides by antigen-presenting cells (APCs).
Manzenrieder, Florian, Elfriede Noessner, Noessner, Elfriede, Bendz, H., Buchner, J., Bendz, Henriette, Johannes Buchner, Nößner, E., Issels, Rolf D., Florian Manzenrieder, Kessler, H., Rolf D. Issels, Pandya, M.J., Manzenrieder, F., Issels, R.D., Kessler, Horst, Pandya, Maya J., Henriette Bendz, Maya J. Pandya, Buchner, Johannes, Horst Kessler   +20 more
core   +1 more source

Immunotherapeutic targeting of membrane Hsp70-expressing tumors using recombinant human granzyme B [PDF]

, 2012
Background: We have previously reported that human recombinant granzyme B (grB) mediates apoptosis in membrane heat shock protein 70 (Hsp70)-positive tumor cells in a perforin-independent ...
Axel Walch, Alan G Pockley, Foulds, GA, Pockley, A. G., Foulds, G. A., Doss, B. T., Pockley, AG, Stangl Stefan, Kirschner, A., Foulds, G.A., Gehrmann, M., Multhoff, G., Walch Axel, Doß Brigitte T., Walch, A.K., Kirschner, A, Gehrmann Mathias, Gemma A Foulds, Stangl, S., Walch, A., Doß, B.T., Pockley, A.G., Multhoff, G, Sievert Wolfgang, Stefan Stangl, Stangl, S, Pockley Alan G., Mathias Gehrmann, Multhoff Gabriele, Sievert, W, Sievert, W., Foulds Gemma A., Andreas Kirschner, Kirschner Andreas, Wolfgang Sievert, Gehrmann, M, Gabriele Multhoff, Doß, BT, Brigitte T Doss, Walch, A   +39 more
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Mitochondrial heat shock protein 70, a molecular chaperone for proteins encoded by mitochondrial DNA [PDF]

, 1994
Mitochondrial heat shock protein 70 (mt-Hsp70) has been shown to play an important role in facilitating import into, as well as folding and assembly of nuclear-encoded proteins in the mitochondrial matrix.
W Neupert, Herrmann, Johannes M., Stuart, Rosemary A., Neupert, Walter, J M Herrmann, Craig, Elisabeth A., E A Craig, R A Stuart   +7 more
core   +1 more source