Results 21 to 30 of about 153,832 (262)

Heat shock protein 70 promotes lipogenesis in HepG2 cells

Lipids in Health and Disease, 2018
Background The increasing prevalence of non-alcoholic fatty liver disease (NAFLD) has followed the international rise in obesity rates. Multiple mechanisms are involved in NAFLD, including endoplasmic reticulum stress and oxidative stress.
Jielei Zhang, Nengguang Fan, Yongde Peng
doaj   +1 more source

Effect of heat shock protein 70 polymorphism on thermotolerance in Tharparkar cattle [PDF]

Veterinary World, 2016
Aim: Out of various members of heat shock protein (HSP) superfamily which act a molecular chaperon by binding to the denaturing protein thus stabilizing them and preserving their activity, HSP70 are of major importance in thermotolerance development ...
Sandip Bhat , Pushpendra Kumar , Neeraj Kashyap , Bharti Deshmukh , Mahesh Shivanand Dige , Bharat Bhushan , Anuj Chauhan , Amit Kumar , Gyanendra Singh   +8 more
doaj   +1 more source

Implications of sperm heat shock protein 70-2 in bull fertility [PDF]

Veterinary World, 2022
Heat shock protein 70 (HSP70) is one of the most abundant chaperone proteins. Their function is well documented in facilitating the protein synthesis, translocation, de novo folding, and ordering of multiprotein complexes.
Zulfi Nur Amrina Rosyada, Mokhamad Fakhrul Ulum, Ligaya I. T. A. Tumbelaka, Dedy Duryadi Solihin, Bambang Purwantara, Erdogan Memili   +5 more
doaj   +1 more source

CLINICAL SIGNIFICANCE OF SERUM AND URINARY HEAT SHOCK PROTEIN 70 LEVEL ASSESSMENT IN PATIENTS WITH CHRONIC GLOMERULONEPHRITIS

Alʹmanah Kliničeskoj Mediciny, 2016
The levels of urinary heat shock protein-70 and serum antibodies to the heat shock protein-70 were assessed in 79 patients with different course variants of the chronic glomerulonephritis. The indices studied were higher in patients with an active course
N. V. Chebotaryova, I. N. Bobkova, N. I. Neprintseva, L. V. Kozlovskaya   +3 more
doaj   +1 more source

Aspirin relieves the calcification of aortic smooth muscle cells by enhancing the heat shock response

Pharmaceutical Biology, 2022
Context Vascular calcification is a major complication of chronic renal failure, which has been identified as an active process partly driven by osteogenic transition of vascular smooth muscle cells (VSMCs).
Quanquan Shen, Qian Chen, Yang Liu, Xiang Xue, Xiaogang Shen, Qiang He, Guokun Wang, Fei Han   +7 more
doaj   +1 more source

Serum levels of Heat Shock Protein-70 in Patients with Oral Lichen Planus

Balkan Journal of Dental Medicine, 2014
Usually increased presence of Heat Shock Proteins (HSPs) is considered to mediate inflammation process in Oral Lichen Planus (OLP) lesions, but in contrast HSP-70 expression found to be stable or even decreased in those lesions. The purpose of this study
Albanidou-Farmaki E., Andreadis D., Poulopoulos A., Farmakis K., Markopoulos A.   +4 more
doaj   +1 more source

Investigation of heat shock protein 70 gene polymorphism in Khuzestan native chickens [PDF]

مجله بیوتکنولوژی کشاورزی, 2020
Objective Heat shock protein 70 (Hsp70) are a family of molecular chaperones, which promote protein folding and participate in many cellular functions. The purpose of the study was to identify the polymorphisms of heat shock protein 70 gene of Khuzestan ...
Mahmood Nazari, Fatemeh Salabi, Sosan Radpoor   +2 more
doaj   +1 more source

The Link That Binds: The Linker of Hsp70 as a Helm of the Protein’s Function

Biomolecules, 2019
The heat shock 70 (Hsp70) family of molecular chaperones plays a central role in maintaining cellular proteostasis. Structurally, Hsp70s are composed of an N-terminal nucleotide binding domain (NBD) which exhibits ATPase activity, and a C-terminal ...
Graham Chakafana, Tawanda Zininga, Addmore Shonhai   +2 more
doaj   +1 more source

Prospective determination of heat shock protein serum levels in Saskatchewan women during pregnancyAJOG Global Reports at a Glance

AJOG Global Reports
BACKGROUND: The stress proteins, heat shock protein 27, heat shock protein 70, and αB-crystallin, have all been detected in human serum under normal and disease conditions.
Lindsey Broberg, MD, Ewa I. Miskiewicz, PhD, Jocelyne Martel, MD, Daniel J. MacPhee, PhD   +3 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source