Results 251 to 260 of about 310,958 (294)

Antidiabetic Potential of Ligands from NEIST_PMIB_06, Bacterium Associated with Hawaijar (Fermented Soy Food): Insight from in Vitro and in Silico Studies

ChemFoodChem, EarlyView.
ABSTRACT In this study, a bacterium (NEIST_PMIB_06) was isolated from Hawaijar, a fermented soy food from Manipur, Northeast India. The bacterium was inoculated and incubated to isolate bioactive compounds. Liquid‐liquid extraction was performed to obtain extracts (cell‐free and cell‐based), and their efficacy was evaluated.
A Ibeyaima, Hiranmoy Barman, Prasenjit Manna   +2 more
wiley   +1 more source

A Michaelis‐Arbuzov‐Type Pathway to a Protected 2ʹ‐Deoxy‐2ʹ‐Selenomethyl‐Adenosine‐3ʹ,5ʹ‐Phosphoroselenolate Guanosine Dinucleotide for Use in Modified m7G Cap Synthesis

Chemistry – A European Journal, EarlyView.
Here we report a synthesis of the dinucleotide 4 for a projected future total synthesis of the m7G cap 1. Highlights of the route include: 1) a 3ʹ‐H‐phosphonate/5ʹ‐selenocyanate Michaelis‐Arbuzov coupling to forge the 3ʹ,5ʹ‐phosphoroselenolate; 2) an Amosova reductive selenomethylation to install the 2ʹ‐SeMe; 3) a solid CPR II 5ʹ‐O‐phosphitylation; and
K. Lawrence E. Hale, Helen O. McCarthy, Mark G. McLaughlin   +2 more
wiley   +1 more source

Apatorsen plus docetaxel versus docetaxel alone in platinum-resistant metastatic urothelial carcinoma (Borealis-2) [PDF]

, 2018
et al,, Picus, Joel
core   +1 more source

Waste activated sludge high‐rate treatment of septage: Biodegradability studies and contact phase trials towards a cleaner environment

The Canadian Journal of Chemical Engineering, EarlyView.
Abstract The waste activated sludge high‐rate (WASHR) process, developed in our previous study, is used for septic wastewater treatment. This high‐rate contact stabilization pre‐treatment uses typical waste streams found in wastewater treatment plants to reduce a portion of the loadings on the main treatment trains.
Arman Shirali, Melody Blythe Johnson, Mehrab Mehrvar   +2 more
wiley   +1 more source

Purification, Fluorescent Labeling, and Detyrosination of Mammalian Cell Tubulin for Biochemical Assays

Cytoskeleton, EarlyView.
ABSTRACT Microtubules play essential roles in numerous cellular processes. All microtubules are built from the protein tubulin, yet individual microtubules can differ spatially and temporally due to their tubulin isotype composition and post‐translational modifications (PTMs).
Ezekiel C. Thomas, Yang Yue, Morgan L. Pimm, Takashi Hotta, Ryoma Ohi, Kristen J. Verhey   +5 more
wiley   +1 more source

Silibinin Targeting Heat Shock Protein 90 Represents a Novel Approach to Alleviate Nonalcoholic Fatty Liver Disease by Simultaneously Lowering Hepatic Lipotoxicity and Enhancing Gut Barrier Function. [PDF]

ACS Pharmacol Transl Sci
Yan B, Zheng X, Chen X, Hao H, Shen S, Yang J, Wang S, Sun Y, Xian J, Shao Z, Fu T.   +10 more
europepmc   +1 more source

Molecular cloning and expression of a hexameric Heat Shock Factor subject to nagtive regulation [PDF]

, 1990
Becker, Peter B., Clos, J., Lambert, K., Westwood, J., Wilson, S., Wu, Chun-Guey   +5 more
core  

Hot and Salty: Assessing ecological stress in New Hampshire streams at community, population, and molecular levels [PDF]

, 2018
Villamagna, Amy Marie
core   +1 more source

Efficacy and Safety of the Heat Shock Protein 90 Inhibitor RGRN-305 in Hidradenitis Suppurativa: A Parallel-Design Double-Blind Trial.

JAMA Dermatol
Ben Abdallah H, Bregnhøj A, Emmanuel T, Ghatnekar G, Johansen C, Iversen L.   +5 more
europepmc   +1 more source