Results 21 to 30 of about 234,613 (299)

Heat Shock Proteins as Immunomodulants

Molecules, 2018
Heat shock proteins (Hsps) are conserved molecules whose main role is to facilitate folding of other proteins. Most Hsps are generally stress-inducible as they play a particularly important cytoprotective role in cells exposed to stressful conditions ...
Tawanda Zininga, Lebogang Ramatsui, Addmore Shonhai   +2 more
doaj   +1 more source

Heat-Shock Proteins in Neuroinflammation

Frontiers in Pharmacology, 2019
The heat-shock response, one of the main pro-survival mechanisms of a living organism, has evolved as the biochemical response of cells to cope with heat stress.
Brigitta Dukay, Brigitta Dukay, Bálint Csoboz, Melinda E. Tóth   +3 more
doaj   +1 more source

Changes in the transcriptome of morula-stage bovine embryos caused by heat shock: relationship to developmental acquisition of thermotolerance

Reproductive Biology and Endocrinology, 2013
Background While initially sensitive to heat shock, the bovine embryo gains thermal resistance as it progresses through development so that physiological heat shock has little effect on development to the blastocyst stage by Day 5 after insemination ...
Sakatani Miki, Bonilla Luciano, Dobbs Kyle B, Block Jeremy, Ozawa Manabu, Shanker Savita, Yao JiQiang, Hansen Peter J   +7 more
doaj   +1 more source

Heat shock proteins on beef quality [PDF]

Pesquisa Agropecuária Brasileira, 2018
: The objective of this work was to quantify heat shock proteins (HSP) 27 and 70 in the Longissimus dorsi muscle of cattle during aging and to check their potential as biomarkers for meat quality.
Cristina Tschorny Moncau, Alessandra Fernandes Rosa, Joanir Pereira Eler, Júlio César de Carvalho Balieiro   +3 more
doaj   +1 more source

Functions and Therapeutic Use of Heat Shock Proteins in Hepatocellular Carcinoma

Livers
Heat shock proteins are intracellular proteins expressed in prokaryotes and eukaryotes that help protect the cell from stress. They play an important role in regulating cell cycle and cell death, work as molecular chaperons during the folding of newly ...
Ramakrushna Paul, Smriti Shreya, Shweta Pandey, Srishti Shriya, Aya Abou Hammoud, Christophe F. Grosset, Buddhi Prakash Jain   +6 more
doaj   +1 more source

The Emerging Role of Heat Shock Factor 1 (HSF1) and Heat Shock Proteins (HSPs) in Ferroptosis

Pathophysiology, 2023
Cells employ a well-preserved physiological stress response mechanism, termed the heat shock response, to activate a certain type of molecular chaperone called heat shock proteins (HSPs).
Iman Aolymat, Ma’mon M. Hatmal, Amin N. Olaimat   +2 more
doaj   +1 more source

Molecular Bases of Heat Stress Responses in Vegetable Crops With Focusing on Heat Shock Factors and Heat Shock Proteins

Frontiers in Plant Science, 2022
The effects of the climate change including an increase in the average global temperatures, and abnormal weather events such as frequent and severe heatwaves are emerging as a worldwide ecological concern due to their impacts on plant vegetation and crop
Yeeun Kang, Kwanuk Lee, Ken Hoshikawa, Myeongyong Kang, Seonghoe Jang   +4 more
doaj   +1 more source

Minimal Yet Powerful: The Role of Archaeal Small Heat Shock Proteins in Maintaining Protein Homeostasis

Frontiers in Molecular Biosciences, 2022
Small heat shock proteins (sHsp) are a ubiquitous group of ATP-independent chaperones found in all three domains of life. Although sHsps in bacteria and eukaryotes have been studied extensively, little information was available on their archaeal homologs
Mousam Roy, Koustav Bhakta, Abhrajyoti Ghosh   +2 more
doaj   +1 more source

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Heat shock proteins as hallmarks of cancer: insights from molecular mechanisms to therapeutic strategies

Journal of Hematology & Oncology
Heat shock proteins are essential molecular chaperones that play crucial roles in stabilizing protein structures, facilitating the repair or degradation of damaged proteins, and maintaining proteostasis and cellular functions.
Wei-Fang Zuo, Qiwen Pang, Xinyu Zhu, Qian-Qian Yang, Qian Zhao, Gu He, Bo Han, Wei Huang   +7 more
doaj   +1 more source