Results 51 to 60 of about 218,902 (163)

Targeting heat shock proteins to modulate α-synuclein toxicity

open access: yesTherapeutic Advances in Neurological Disorders, 2014
Parkinson’s disease is a slowly progressive neurodegenerative disorder typically characterized by the loss of dopaminergic neurons within the substantia nigra pars compacta, and the intraneuronal deposition of insoluble protein aggregates chiefly ...
Daryl Rhys Jones   +2 more
doaj   +1 more source

Barcoding heat shock proteins to human diseases: looking beyond the heat shock response

open access: yesDisease Models & Mechanisms, 2014
There are numerous human diseases that are associated with protein misfolding and the formation of toxic protein aggregates. Activating the heat shock response (HSR) – and thus generally restoring the disturbed protein homeostasis associated with such ...
Vaishali Kakkar   +4 more
doaj   +1 more source

Partners in Mischief: Functional Networks of Heat Shock Proteins of Plasmodium falciparum and Their Influence on Parasite Virulence

open access: yesBiomolecules, 2019
The survival of the human malaria parasite Plasmodium falciparum under the physiologically distinct environments associated with their development in the cold-blooded invertebrate mosquito vectors and the warm-blooded vertebrate human host requires a ...
Michael O. Daniyan   +2 more
doaj   +1 more source

Heat shock proteins in male infertility: recent advances and clinical implications

open access: yesFrontiers in Cell and Developmental Biology
The decline in male sperm quality has become a global concern for male reproductive health. Research indicates that heat stress is an important external factor that contributes to male infertility, potentially promoting germ cell apoptosis, disrupting ...
Zhongnan Wu   +8 more
doaj   +1 more source

Heat shock proteins and oral diseases

open access: yesSRM Journal of Research in Dental Sciences, 2012
Heat shock proteins (HSPs) are substances expressed in response to elevated temperatures or other cellular stress. They are highly conserved proteins inhabiting nearly all subcellular compartments and are found in all organisms and all cell types. When a
G Suresh Babu   +3 more
doaj  

Small heat shock proteins and biomolecular condensates. [PDF]

open access: yesCell Mol Life Sci
Crotti S, Secco V, Morini M, Carra S.
europepmc   +1 more source

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