Results 61 to 70 of about 569,417 (300)

Menin links the stress response to genome stability in Drosophila melanogaster. [PDF]

open access: yesPLoS ONE, 2010
The multiple endocrine neoplasia type I gene functions as a tumor suppressor gene in humans and mouse models. In Drosophila melanogaster, mutants of the menin gene (Mnn1) are hypersensitive to mutagens or gamma irradiation and have profound defects in ...
Maria Papaconstantinou   +6 more
doaj   +1 more source

Harnessing Fungal Biowelding for Constructing Mycelium‐Engineered Materials

open access: yesAdvanced Engineering Materials, EarlyView.
Mycelium‐bound composites (MBCs) offer low‐carbon alternatives for construction, yet interfacial bonding remains a critical challenge. This review examines fungal biowelding as a biocompatible adhesive, elucidating mycelium‐mediated interfacial mechanisms and their role in material assembly. Strategies to optimize biowelding are discussed, highlighting
Xue Brenda Bai   +2 more
wiley   +1 more source

Characterizing primary transcriptional responses to short term heat shock in Down syndrome.

open access: yesPLoS ONE
Heat shock stress induces genome-wide changes in transcription regulation, activating a coordinated cellular response to enable survival. We noticed many heat shock genes are up-regulated in blood samples from individuals with trisomy 21.
Joseph F Cardiello   +3 more
doaj   +1 more source

Mechanism of protonophores-mediated induction of heat-shock response in Escherichia coli

open access: yesBMC Microbiology, 2009
Background Protonophores are the agents that dissipate the proton-motive-force (PMF) across E. coli plasma membrane. As the PMF is known to be an energy source for the translocation of membrane and periplasmic proteins after their initial syntheses in ...
Saha Swati   +3 more
doaj   +1 more source

Influence of Sample Preparation and Processing Procedures on the Thermal Diffusivity of MgO‐C Refractories

open access: yesAdvanced Engineering Materials, EarlyView.
The thermal diffusivity of MgO‐C refractories is highly sensitive to sample preparation and processing procedures. In this article, the effects of coking sequence, machining conditions, structural inhomogeneity, and graphite coating application on measurements using laser flash apparatus are systematically investigated.
Luyao Pan   +4 more
wiley   +1 more source

Barcoding heat shock proteins to human diseases: looking beyond the heat shock response

open access: yesDisease Models & Mechanisms, 2014
There are numerous human diseases that are associated with protein misfolding and the formation of toxic protein aggregates. Activating the heat shock response (HSR) – and thus generally restoring the disturbed protein homeostasis associated with such ...
Vaishali Kakkar   +4 more
doaj   +1 more source

Multi-level interactions between heat shock factors, heat shock proteins, and the redox system regulate acclimation to heat [PDF]

open access: yes, 2015
Citation: Driedonks, N., Xu, J., Peters, J. L., Park, S., & Rieu, I. (2015). Multi-level interactions between heat shock factors, heat shock proteins, and the redox system regulate acclimation to heat. Frontiers in Plant Science, 6(NOVEMBER). doi:10.3389/
Driedonks, N.   +4 more
core   +3 more sources

Characterization of a Recyclate‐Based MgO‐Steel Composite As‐Sintered Inert Anode Candidate After Exposure to Cryolite Electrolysis

open access: yesAdvanced Engineering Materials, EarlyView.
Carbon‐free inert anodes are essential for decarbonizing aluminum electrolysis. This study investigates a recyclate‐based MgO‐316L steel composite anode tested under galvanostatic Hall–Héroult conditions in cryolite at 1000°C. Microstructural analysis reveals selective MgO fluorination, spinel and oxide layer formation, electrolyte infiltration, and ...
Serhii Yaroshevskyi   +7 more
wiley   +1 more source

Heat shock suppresses the innate immune response of bovine endometrial epithelial cells

open access: yesReproduction and Fertility
With rising global temperatures, it is imperative to determine the impact of heat stress on the physiology of food-producing animals. Dairy cows are susceptible to uterine diseases that reduce fertility.
Arslan Tariq   +5 more
doaj   +1 more source

Reprogramming of the transcriptome after heat stress mediates heat hormesis in Caenorhabditis elegans

open access: yesNature Communications, 2023
Transient stress experiences not only trigger acute stress responses, but can also have long-lasting effects on cellular functions. In Caenorhabditis elegans, a brief exposure to heat shock during early adulthood extends lifespan and improves stress ...
Fan Xu   +7 more
doaj   +1 more source

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