Results 31 to 40 of about 588,170 (264)
Open PhysicsScientific inquiry into effective numerical methods for modelling complex physical processes has led to the investigation of fluid dynamics, mainly when non-Newtonian properties and complex heat sources are involved.
Arif Muhammad Shoaib +2 more
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Energies, 2020 This paper focuses on the problem of thermoelectric cooler waste heat recovery and utilization, and proposes taking the waste heat together with the original heat source as the input heat source of the integrated thermoelectric generation–cooling system.
Jia Yu +4 more
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Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
HEAT TRANSFER IN ENCLOSURES FILLED WITH NANOFLUIDS IN CASE OF THE FRACTIONAL DERIVATIVES [PDF]
Assiut University Journal of Multidisciplinary Scientific Research, 2019 In this article, influences of the fractional derivatives on the heat transfer enhancement by free convective flow of nanofluids in a square enclosure that includes a heat source at the bottom are examined.
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Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
机车电传动, 2011 By comparing laminar and turbulent models, the flow regime of water-cooling plate with straight channels was researched; the results showed that the average velocities were different in channels, and it was improper to set the flow regime of all channels
丁杰, 李江红, 陈燕平, 张陈林
doaj
SUBSTATIONS OF DISTRICT HEATING SYSTEMS WITH PULSE COOLANT CIRCULATION
Вестник Дагестанского государственного технического университета: Технические науки, 2017 . Objectives The aim of the study is to generalise the results of the application of technologies and means for organising pulse coolant flow within a district heating system in order to increase its energy efficiency based on the organisation of local ...
Andrey N. Makeev
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FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source