Results 51 to 60 of about 1,636,472 (355)

Examining Stress Relaxation in a Dissimilar Metal Weld Subjected to Postweld Heat Treatment [PDF]

, 2018
Dissimilar metal welds are often required in nuclear power plants to join components made from austenitic steels to those from ferritic steels, particularly in fast breeder reactor plants, in order to join the intermediate heat exchanger to the steam ...
Abburi Venkata, Abburi Venkata, Brown, Chuvas, Dong, Funderburk., Hossain, Hosseinzadeh, Kwon, Leggatt., McLean, Muransky, Newell, Olson, Prime, Prime, Razakanaivo, Richter-Trummer, Serizawa, Shan, Shilbi, Sireesha, Sulaiman, Taniguchi, Toparli, Urevc, Wimpory, Xie, Yaghi, Zhang, Zondi.   +30 more
core   +4 more sources

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Effects of Chronic and Acute Heat Stress on the Cardiac Expression of Antioxidative and Anti-Inflammatory Genes in Chicks [PDF]

Brazilian Journal of Poultry Science
Heat stress can affect several biological pathways. This study aimed to compare the effects of chronic and acute heat stress on the oxidative status and inflammatory responses of chick’s hearts. Chronic and acute heat stress were induced in chicks, heart
NK Bastaki, JZ Almomen, TA Albarjas
doaj   +1 more source

Acute Heat Stress and Reduced Nutrient Intake Alter Intestinal Proteomic Profile and Gene Expression in Pigs. [PDF]

PLoS ONE, 2015
Heat stress and reduced feed intake negatively affect intestinal integrity and barrier function. Our objective was to compare ileum protein profiles of pigs subjected to 12 hours of HS, thermal neutral ad libitum feed intake, or pair-fed to heat stress ...
Sarah C Pearce, Steven M Lonergan, Elisabeth Huff-Lonergan, Lance H Baumgard, Nicholas K Gabler   +4 more
doaj   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Heat stress and copper supplementation in pigs

California Agriculture, 1989
Controlled feeding trials at UC Davis found no connection between temperature stress and response to copper supplementation, but confirmed overall effects of heat stress on pigs.
H Heitman, S Morrison, K Parker
doaj  

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Sprinkling cattle for control of heat stress

California Agriculture, 1973
Sprinkling cattle, under shades, during the summer in the Imperial Valley for 1 minute every 30 minutes when the temperature was above 80°F (27°C)—resulted in significantly higher feed consumption and rate of gain, compared with cattle under shades but ...
S Morrison, R Givens, G Lofgreen
doaj  

A comparative analysis of accelerating humid and dry heat stress in India

Environmental Research Communications
Extreme humid heat stress poses distinct challenges to human health and productivity that cannot be mitigated solely by heat action plans designed for dry heat stress. This study investigates the trends in extreme heat stress, differentiating between dry
Jency Maria Sojan, Jayaraman Srinivasan
doaj   +1 more source

ERF49 mediates brassinosteroid regulation of heat stress tolerance in Arabidopsis thaliana

BMC Biology, 2022
Background Heat stress is a major abiotic stress affecting the growth and development of plants, including crop species. Plants have evolved various adaptive strategies to help them survive heat stress, including maintaining membrane stability, encoding ...
Xia Chen, Huidan Xue, Liping Zhu, Huiqin Wang, Hao Long, Jun Zhao, Funing Meng, Yunfei Liu, Yuan Ye, Xiaomin Luo, Zhi Liu, Guanghui Xiao, Shengwei Zhu   +12 more
doaj   +1 more source