Results 41 to 50 of about 128,538 (249)

Association Between Work‐Related Hyperthermia Emergency Department Visits and Ambient Heat in Five Southeastern States, 2010–2012—A Case‐Crossover Study

GeoHealth, 2020
The objective of this study is to assess ambient temperatures' and extreme heat events' contribution to work‐related emergency department (ED) visits for hyperthermia in the southeastern United States to inform prevention. Through a collaborative network
Jeffrey Shire, Ambarish Vaidyanathan, Michelle Lackovic, Terry Bunn   +3 more
doaj   +1 more source

Heat stress affects the milk yield, milk composition, serum oxidative status, and metabolites of Holstein cows during mid-lactation

Czech Journal of Animal Science, 2023
Seasonal heat stress and metabolic disorders during mid-lactation are the main factors limiting production in Holstein cows, and several proteins and molecules involved in metabolic pathways are altered in response to stress.
Xue Chen, Yongqiang Li, Jun Xiao, Jianan Dong, Wei Zhao, Zhiyi Han, Liang Xin, Guixin Qin, Tao Wang, Yuguo Zhen, Zhe Sun, Xuefeng Zhang   +11 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Lo que el sector agrícola de Florida necesita saber sobre las enfermedades relacionadas al calor (ERC)

EDIS
Mientras el clima de Florida lo hace ideal para producir una amplia variedad de cultivos, la intensidad del calor y la humedad también pueden representar peligros importantes para quienes trabajan en la agricultura.
Paul Monaghan, Karissa Raskin, María Morera, Antonio Tovar, Valerie Mac, Joan Flocks, Marlia Bosques Martínez, Jonael Bosques, Francisco P. Rivera Meléndez   +8 more
doaj   +3 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Prevalence and influencing factors of occupational stress and sleep disorders among 3 key occupational groups in Guizhou Province

环境与职业医学
BackgroundWorking night shifts is common in the secondary industry workers, and usually with long weekly working hours. They are prone to occupational stress and sleep disorders, which may seriously affect their physical and mental health and work ...
Wenlei HE, Junhong YANG, Yaoyao HE, Shaofang YANG, Songlin JIAO   +4 more
doaj   +1 more source

Selenomethionine alleviates environmental heat stress induced hepatic lipid accumulation and glycogen infiltration of broilers via maintaining mitochondrial and endoplasmic reticulum homeostasis

Redox Biology, 2023
With the increasing of global mean surface air temperature, heat stress (HS) induced by extreme high temperature has become a key factor restricting the poultry industry.
Jinzhong Jing, Huijin Zeng, Quanjun Shao, Jiayong Tang, Longqiong Wang, Gang Jia, Guangmang Liu, Xiaoling Chen, Gang Tian, Jingyi Cai, Bo Kang, Lianqiang Che, Hua Zhao   +12 more
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Heat Stress Modulates WDR5‐Mediated H3K4me3 Modification to Induce Melanogenesis via Activating CX3CL1/CX3CR1 Axis

Advanced Science
The skin's unique thermosensitivity renders it exceptionally responsive to thermal perturbations, wherein heat stress exposure disrupts cutaneous homeostasis and activates pigmentary pathways.
Yushan Zhang, Ling Jiang, Yibo Hu, Chuhan Fu, Jinhua Huang, Jing Chen, Qinghai Zeng   +6 more
doaj   +1 more source