Results 51 to 60 of about 5,306,758 (279)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Mechanisms underlying the Effects of Heat Stress on Intestinal Integrity, Inflammation, and Microbiota in Chickens

The Journal of Poultry Science, 2023
Poultry meat and egg production benefits from a smaller carbon footprint, as well as feed and water consumption, per unit of product, than other protein sources.
Motoi Kikusato, Masaaki Toyomizu
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Lo que el sector agrícola de Florida necesita saber sobre las enfermedades relacionadas al calor (ERC)

EDIS
Mientras el clima de Florida lo hace ideal para producir una amplia variedad de cultivos, la intensidad del calor y la humedad también pueden representar peligros importantes para quienes trabajan en la agricultura.
Paul Monaghan, Karissa Raskin, María Morera, Antonio Tovar, Valerie Mac, Joan Flocks, Marlia Bosques Martínez, Jonael Bosques, Francisco P. Rivera Meléndez   +8 more
doaj   +3 more sources

Effects of N-Acetyl-L-Cysteine on Serum Indices and Hypothalamic AMPK-Related Gene Expression Under Chronic Heat Stress

Frontiers in Veterinary Science, 2022
This study aims to investigate the effect of heat stress on the physiological metabolism of young laying hens and whether N-acetyl-l-cysteine (NAC) can effectively alleviate heat stress.
Zhengqing Li, Yulan Zhao, Yu Zhuang, Zheng Xu, Cong Wu, Ping Liu, Guoliang Hu, Guyue Li, Wei Chen, Xiaona Gao, Xiaoquan Guo   +10 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Prevalence and influencing factors of occupational stress and sleep disorders among 3 key occupational groups in Guizhou Province

环境与职业医学
BackgroundWorking night shifts is common in the secondary industry workers, and usually with long weekly working hours. They are prone to occupational stress and sleep disorders, which may seriously affect their physical and mental health and work ...
Wenlei HE, Junhong YANG, Yaoyao HE, Shaofang YANG, Songlin JIAO   +4 more
doaj   +1 more source

Association Between Work‐Related Hyperthermia Emergency Department Visits and Ambient Heat in Five Southeastern States, 2010–2012—A Case‐Crossover Study

GeoHealth, 2020
The objective of this study is to assess ambient temperatures' and extreme heat events' contribution to work‐related emergency department (ED) visits for hyperthermia in the southeastern United States to inform prevention. Through a collaborative network
Jeffrey Shire, Ambarish Vaidyanathan, Michelle Lackovic, Terry Bunn   +3 more
doaj   +1 more source

Heat stress affects the milk yield, milk composition, serum oxidative status, and metabolites of Holstein cows during mid-lactation

Czech Journal of Animal Science, 2023
Seasonal heat stress and metabolic disorders during mid-lactation are the main factors limiting production in Holstein cows, and several proteins and molecules involved in metabolic pathways are altered in response to stress.
Xue Chen, Yongqiang Li, Jun Xiao, Jianan Dong, Wei Zhao, Zhiyi Han, Liang Xin, Guixin Qin, Tao Wang, Yuguo Zhen, Zhe Sun, Xuefeng Zhang   +11 more
doaj   +1 more source