Results 71 to 80 of about 309,739 (302)
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Journal of Ginseng Research, 2019 Background: Increases in the average global temperature cause heat stress–induced disorders by disrupting homeostasis. Excessive heat stress triggers an imbalance in the immune system; thus protection against heat stress is important to maintain immune ...
Ji-Hyeon Song +5 more
doaj +1 more source
Poultry Science, 2023 : Chronic heat stress has detrimental effects on the growth performance of broilers, and the potential mechanism is under exploration. In this study, the protein carbonyl modification was introduced to glycolytic enzymes to evaluate its relationship with
Yingsen Liu +6 more
doaj +1 more source
The association between overall health, psychological distress, and occupational heat stress among a large national cohort of 40,913 Thai workers [PDF]
, 2016 BACKGROUND Occupational heat stress is a well-known problem, particularly in tropical countries, affecting workers, health and well-being. There are very few recent studies that have reported on the effect of heat stress on mental health, or overall ...
Kjellstrom, Tord +5 more
core +1 more source
Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications
FEBS Open Bio, EarlyView.This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley +1 more source
Heat Stress Alters the Intestinal Microbiota and Metabolomic Profiles in Mice
Frontiers in Microbiology, 2021 BackgroundHeat stress has negative effects on the intestinal health of humans and animals. However, the impact of heat stress on intestinal microbial and metabolic changes remains elusive.
Chaoyue Wen +19 more
doaj +1 more source
Health Effects Associated With Electronic Cigarette Use: Automated Mining of Online Forums. [PDF]
, 2020 BACKGROUND:Our previous infodemiological study was performed by manually mining health-effect data associated with electronic cigarettes (ECs) from online forums.
Hristidis, Vagelis +3 more
core
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
Personal risk factors during heat stress exposure in workplace
بهداشت و ایمنی کار, 2017 Introduction: Heat stress is caused by many factors such as individual factors, environmental factors, and management factors. Individual risk factors can decrease the heat tolerance, and play an important role in heat stress disorders incidence. The aim
Parvin Nassiri +7 more
doaj
陆军军医大学学报Objective To explore the clinical characteristics of patients with heat illness and the related factors for progression to heatstroke so as to provide a basis for early clinical intervention. Methods A case-control study design was adopted. A total
WANG Yanyan +3 more
doaj +1 more source