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Journal of Intensive Care, 2018 Background Heat stroke is a life-threatening injury requiring neurocritical care; however, heat stroke has not been completely examined due to several possible reasons, such as no universally accepted definition or classification, and the occurrence of ...
Toru Hifumi +3 more
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Successful Heat Stroke-Induced Pediatric Acute Liver Failure Treatment With N-Acetylcysteine Case Report [PDF]
Critical Care ExplorationsBACKGROUND:. Previously healthy children are at risk of developing exertional heat stroke when experiencing extreme heat. Pediatric clinicians in primary care, emergency department, and critical care settings should be versed in the management of ...
Archana Anandakrishnan, DO +2 more
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The pathogenesis and therapeutic strategies of heat stroke-induced endothelial injury [PDF]
Frontiers in Cell and Developmental BiologyHeat stroke is a severe and life-threatening condition characterized by elevated core body temperature and central nervous system dysfunction, often accompanied by multi-organ damage.
Shaokang Wang +5 more
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Single-cell sequencing-based study of ferroptosis mechanisms in heat stroke: identification of key biomarkers and dynamic analysis of the immune microenvironment [PDF]
BMC Medical GenomicsBackground Heat stroke, caused by excessive heat production or impaired dissipation, often results from prolonged heat exposure or strenuous activity. Ferroptosis, a novel form of programmed cell death, has been implicated in its pathogenesis, though its
Defeng Yin +9 more
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Lessons From Heat Stroke for Understanding Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Frontiers in Neurology, 2021 We here provide an overview of the pathophysiological mechanisms during heat stroke and describe similar mechanisms found in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS).
Dominic Stanculescu +5 more
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Journal of Neuroinflammation, 2021 Background Patients with prior illness are more vulnerable to heat stroke-induced injury, but the underlying mechanism is unknown. Recent studies suggested that NLRP3 inflammasome played an important role in the pathophysiology of heat stroke. Methods In
Zi-Teng Zhang +10 more
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Exertional heat stroke: pathophysiology and risk factors
BMJ Medicine, 2022 Exertional heat stroke, the third leading cause of mortality in athletes during physical activity, is the most severe manifestation of exertional heat illnesses. Exertional heat stroke is characterised by central nervous system dysfunction in people with
Christian K Garcia +4 more
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Exertional heat stroke with reversible severe cerebral edema [PDF]
Clinical and Experimental Emergency Medicine, 2021 Severe cerebral edema associated with exertional heat stroke is a major cause of death or disability. However, few studies on severe cerebral edema resulting from heat stroke have reported neuroradiological findings.
Sangkil Lee, Sung-Hyun Lee
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Journal of Pharmacological Sciences, 2005 Heat stroke is characterized by hyperthermia, arterial hypotension, decreased baroreflex sensitivity, and increased serum levels of β-endorphin. Whereas naltrexone may have therapeutic potential in heat stroke, the underlying mechanism remains unclear ...
Yi-Ping Huang +3 more
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Frontiers in Neurology, 2022 BackgroundHeat stroke is a potentially fatal condition that is caused by elevated core temperature. Guillain–Barré syndrome (GBS) induced by heat stroke is extremely rare and has only been reported in few case reports.
Xiao-xiao Ni +3 more
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