Results 101 to 110 of about 9,566,751 (306)

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Heat treatment of welded steel structures /

An updated, revised and expanded version of Professor Burdekin's earlier work of the same title, this book explains this branch of thermal engineering in clear, practical terms.
Croft, D. N.
core  

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source

Effect of Zr on precipitation kinetics of Fe-Cr-Al alloys

Heat Treatment and Surface Engineering
The present work investigated the effect of Zr on the precipitation behavior and mechanical properties of Fe-13.5Cr-4.73Al-2.07Mo-(0.34∼0.45)Nb-(0.65∼0.87)Ta-(0.11∼0.33)Zr (wt. %) alloys.
Ben Niu, Zhenhua Wang, Qing Wang, Sen Ge, Chuang Dong, Ruiqian Zhang   +5 more
doaj   +1 more source

Heat treatment for insect control : developments and applications /

Stored product insects and other pests represent a major hygiene and safety issue to many industries, from food production to building infestation, and issues for timber pallets and packaging.
Hammond, David,author.
core  

Structure, Phase Composition, and Mechanical Properties of ZK51A Alloy with AlN Nanoparticles after Heat Treatment

The paper studies the influence of the content of aluminum nitride nanoparticles on the structure and mechanical properties of the ZK51A magnesium alloy. The microstructure investigations with optical and electron microscopy show that 1 wt.% AlN promotes
Alexander B. Vorozhtsov, Mikhail V. Grigoriev, Anton P. Khrustalev, Anastasia A. Akhmadieva, Ilya A. Zhukov   +4 more
core   +1 more source

Final Heat Treatment as a Possible Solution for the Improvement of Machinability of Pb-Free Brass Alloys

, 2018
Heat treatment was performed in order to improve the machinability of three lead-free extruded and drawn brasses, namely CuZn42 (CW510L), CuZn38As (CW511L), and CuZn36 (C27450), based on the concept of microstructural modification.
George A. Pantazopoulos, Constantine N. David, Constantine N. David, Dimitrios S. Sagris, Alkiviadis S. Paipetis, Anagnostis I. Toulfatzis, George A. Pantazopoulos, Alkiviadis S. Paipetis, Anagnostis I. Toulfatzis, Dimitrios S. Sagris   +9 more
core   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source