Results 101 to 110 of about 1,032,407 (315)

Enhancement of Mechanical Properties of Hot-Forged 6082 Suspension Parts via Rapid IR Heat Treatment [PDF]

, 2018
Post-forging heat treatment is often necessary to achieve the mechanical properties required for aluminum alloy forged parts. In this study, hot-forged 6082 suspension parts are used to study the effect of rapid infrared (IR) heat treatment.
Truan-Sheng Lui, Yi-Ling Chang, Fei-Yi Hung   +2 more
core   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Microstructure, corrosion and electrochemical behavior of Cd-modified Al-5Zn-0.5Mg alloys in 3.5 wt% NaCl solution: A comparative study

Next Materials
This experimental study quantitatively assesses the role of Cd additions (0–1.5 wt%) on phase formation, mechanical properties, and electrochemical behavior of Al-5Zn-0.5Mg casting alloys.
Gamal M. Rashed, Mosaad M. Sadawy, Mohamed A. Elhelaly, Ahmed Abdelkareem, Amr A. Kandil   +4 more
doaj   +1 more source

Effect of Heat Treatment on Pore Architecture and Associated Property Charges in Plasma Sprayed TBCs [PDF]

, 2007
Plasma sprayed TBCs exhibit many interlamellar pores, voids and microcracks. These microstructural features are primarily responsible for the low global stiffnesses and the low thermal conductivities commonly exhibited by such coatings.
Paul, S., Dorfman, M.R., Cipitria, A., Clyne, T.W., Golosnoy, I.O., Xie, L.   +5 more
core  

Microstructure Control for Enhancing the Combination of Strength and Elongation in Ti-6Al-4V through Heat Treatment [PDF]

For the application of Ti-6Al-4V alloys in urban air mobility, safety is very important, so achieving excellent strength and toughness is essential to prevent fractures.
Minsu Jung, Jiyong Park, Seongji Seo
core   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Ti–6Al–4V alloy prepared by laser powder bed fusion of a coarse powder

Heat Treatment and Surface Engineering
A Ti–6Al–4V (wt%) alloy was prepared by laser powder bed fusion (LPBF) of a coarse powder with particle sizes in the range of 50–200 μm. The effect of volume energy density (VED) on cavities/pores, microstructure and mechanical properties of the LPBF ...
Mengmeng Zhang, Yiting Pan, Kai Kang, Tongrui Wang, Dengliang Zhang   +4 more
doaj   +1 more source

An Investigation of Heat Treatment Residual Stress of Type I, II, III for 8Cr4Mo4V Steel Bearing Ring Using FEA-CPFEM-GPA Method [PDF]

The heat treatment residual stress of 8Cr4Mo4V steel bearings seriously affects the contact fatigue life. The micro stress concentration at the carbide interface leads to the initiation of micro cracks.
Jingchuan Zhu, Puchang Cui, Tianpeng Song, Xue Liu, Yong Liu, Tao Xia   +5 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Microstructural evolution in 12% Cr heat-resistant steel during compression deformation at 650°C

Heat Treatment and Surface Engineering
The 12% Cr heat-resistant steel used for critical components of fossil-fired power plants works in high-temperature and high-pressure steam environments for a long time and inevitably undergoes a certain amount of plastic deformation during service. This
Xin You, Yuantao Xu, Kaihao Guo, Chenghui Xia, Xuejun Jin   +4 more
doaj   +1 more source