Results 81 to 90 of about 1,032,407 (315)

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Numerical simulation of stress evolutions in 2A14 aluminum alloy components during solution and aging process

open access: yesHeat Treatment and Surface Engineering, 2022
Aluminum alloys are commonly used in the aerospace industry because of their good specific strength and corrosion resistance. However, reducing residual stresses and machining deformation of aluminum alloy components are the focus of researches.
Yuchen Yang, Xiaofeng Deng, Wei Shi
doaj   +1 more source

Mechanical Properties Improvement of Low Carbon Steel by Combined Heat Treatments [PDF]

open access: yes, 2001
The improvement of the Mechanical properties of the low Carbon steel and increasing its strength, was the goal of some heat treatment technologies developed in the last twenty years. One of these technologies is the Rapid Heat Treatment (RHT), by which
Dobránszky, János, Abou-Jahjah, J.
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

On the Optimization of T6 Heat Treatment Parameters of a Secondary Al-Si-Cu-Mg Foundry Aluminum Alloy: A Microstructural and Mechanical Characterization [PDF]

open access: yes
Foundry aluminum-silicon (Al-Si) alloys, especially those containing Cu and/or Mg, are widely used in casting processes for fabricating lightweight parts. This study focuses on the optimization of the solution heat treatment parameters within the T6 heat
Chiara Soffritti   +4 more
core   +1 more source

Effect of Heat Treatment on Microstructure and Mechanical Properties of Mg-5Zn-1Mn Alloy Tube [PDF]

open access: yes, 2020
The effects of heat treatment on the microstructure, mechanical properties and electrochemical property of the as-extruded Mg-5Zn-1Mn (ZM51) alloy tube are investigated by optical microstructure (OM), X-ray diffractometer (XRD), scanning electron ...
Yingdu Liu   +7 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Heat treatment of welded steel structures / [PDF]

open access: yes
An updated, revised and expanded version of Professor Burdekin's earlier work of the same title, this book explains this branch of thermal engineering in clear, practical terms.
Croft, D. N.
core  

Enhanced Mechanical Properties of Ceramic Rod-Reinforced TWIP Steel Composites: Fabrication, Microstructural Analysis, and Heat Treatment Evaluation [PDF]

open access: yes
This study investigates the development and characterization of ceramic rod-reinforced TWIP (twinning-induced plasticity) steel matrix composites, produced using the lost foam casting technique. Mechanical tests revealed a substantial improvement in both
Zhenggui Li   +3 more
core   +1 more source

Heat Treatment of Sintered Steels – what is different?* [PDF]

open access: yes, 2018
Powder metallurgy ferrous precision parts are employed in numerous industrial sectors. In case of high mechanical loading, as e. g. in automotive applications, heat treatment is frequently required after the press-and-sinter manufacturing.
M. Dlapka   +3 more
core   +1 more source

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