Results 81 to 90 of about 14,701,351 (357)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Microstructure and hardness evolution for LB/M microstructures in a hot working die steel

Heat Treatment and Surface Engineering
Hot working die steels require high hardness, strength and toughness, and there is a strong industrial drive to improve mechanical property combinations through microstructure design and optimization.
Zhizhong Yuan, Yulin Ju, Mingrui Yang, Xiaonong Cheng   +3 more
doaj   +1 more source

Prestorage Heat Treatment and Poststorage Quality of Mango Fruit [PDF]

, 2000
Saichol Ketsa, Sugunya Chidtragool, Susan Lurie   +2 more
openalex   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Effect of Zr on precipitation kinetics of Fe-Cr-Al alloys

Heat Treatment and Surface Engineering
The present work investigated the effect of Zr on the precipitation behavior and mechanical properties of Fe-13.5Cr-4.73Al-2.07Mo-(0.34∼0.45)Nb-(0.65∼0.87)Ta-(0.11∼0.33)Zr (wt. %) alloys.
Ben Niu, Zhenhua Wang, Qing Wang, Sen Ge, Chuang Dong, Ruiqian Zhang   +5 more
doaj   +1 more source

Influence of heat treatment on the microstructure of synthetic nodular cast irons [PDF]

, 2013
Alan Vaško
openalex   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Improving surface hardness of AISI 1045 steels using melamine derived from urea

Heat Treatment and Surface Engineering
AISI 1045 steels are medium carbon steels used in applications that require greater strength and hardness such as gears, railway wheels and tracks, crankshafts, rolls, axles and other structural components.
Elias Tadesse Fisha
doaj   +1 more source

Microfluidic electro‐viscoelastic manipulation of extracellular vesicles

FEBS Open Bio, EarlyView.
The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh, Éva Bozó, Zikrullah Bölükkaya, Artem Zhyvolozhnyi, Anatoliy Samoylenko, Henrikki Liimatainen, Seppo J. Vainio, Caglar Elbuken   +7 more
wiley   +1 more source

Microstructure and mechanical properties of a recycled aluminum alloy fabricated by consolidation of small pieces

Heat Treatment and Surface Engineering
The microstructure and mechanical properties of recycled AA6063 aluminum alloy rods fabricated by hot extrusion of forging compacts formed by upsetting compacts of small AA6063 aluminum alloy pieces with different Fe contents before and after T6 heat ...
Feifei Liu, Deliang Zhang
doaj   +1 more source