Results 91 to 100 of about 2,557,464 (355)

SOLVING OF PROBLEMS OF HEREDITY OF SMELTED CAST IRON AT ОАО “MINSK WORKS OF HEATING EQUIPMENT”

Литьë и металлургия, 2005
The matters of rectification of the negative structure heredity of cast iron, which is transmitted to castings in the result of using of different burden materials at melting of cast iron in cupolas are considered.
L. Z. Pisarenko, V. A. Hatskevich, D. V. Kuis   +2 more
doaj  

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Using of the complex alloy for microalloyed gray cast iron

Литьë и металлургия, 2003
There is shown, that complex alloy, containing titan, aluminium, chrome, nickel and others, is rather an effective additive to cast iron, providing the production of high-quality cast iron without complication of the technological process.
D. A. Hudokormov, L. Z. Pisarenko, D. V. Kuis   +2 more
doaj  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Comparative Analysis of Low- and High-Temperature Chilled Water Systems in Terms of Energy Performance in Office Buildings

Energies
This study examines the impact of chilled water supply parameters on the energy efficiency of an office building’s HVAC system located in a temperate European climate.
Szymon Salamondra, Marta Chludzińska, Jacek Hendiger   +2 more
doaj   +1 more source

Heating the Home [PDF]

, 1951
Helps define your home heating needs that will lead to smart energy and heating decision-making. Shows how different types of heating systems work, how much they cost to operate, and things to do to maintain ...
Harris, Warren Skinner, Konzo, Seichi, Roose, R.W.   +2 more
core  

Surface-induced heating of cold polar molecules

, 2008
We study the rotational and vibrational heating of diatomic molecules placed near a surface at finite temperature on the basis of macroscopic quantum electrodynamics.
E. A. Hinds, E. M. Purcell, I. Mills, J. Brown, J. D. Weinstein, L. Knöll, M. R. Tarbutt, S. Y. Buhmann, Stefan Scheel, Stefan Yoshi Buhmann   +9 more
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

DEVELOPMENT AND MASTERING OF PRODUCTION TECHNOLOGY OF GRINDING BODIES IN DISPOSABLE SAND- CLAY MOLDS

Литьë и металлургия, 2011
The carried out experimental and scientific-research works enabled to organize mass production of grinding bodies, which being successfully tested at the enterprises of building industry of the Republic of Belarus now.
I. A. Busel, I. E. Omelchenko, L. Z. Pisarenko, V. M. Priemko   +3 more
doaj  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source