Results 101 to 110 of about 613,599 (267)
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
FEBS Open Bio, EarlyView.HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
IMPLEMENTATION OF NEW TECHNOLOGIES AND EQUIPMENT TILL 2010 AT GAG “MINSK WORKS OF HEATING EQUIPMENT”
Литьë и металлургия, 2006 The brief perspective of implantation of new production of heating equipment till the year 2010 at ОАО *'MZOO'' is given.
S. F. Lukashevich
doaj
Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription
FEBS Open Bio, EarlyView.In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang +10 more
wiley +1 more source
INTERNATIONAL SCIENTIFIC AND TECHNICAL CONFERENCE OF FOUNDERS AND METALLURGISTS
Литьë и металлургия, 2004 Information about the International Scientific Conference in Minsk on May 19—21 2004 and Celebration of 50-th Anniversary of Cathedra "Machine and Foundry Production"
Ju. P. Bobrov
doaj
FEBS Open Bio, EarlyView.NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks +4 more
wiley +1 more source
Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley +1 more source
RECONSTRUCTION OF THE ANNEALED AND GRAY CAST IRON WORKSHOP AT GAG “MZGG”
Литьë и металлургия, 2005 The advantages of moulding system DISA 230F (Denmark) are given. It is shown that enterprise gets economic effect from reduction of net cost of 1 tone casting of annealed and gray cast iron.
V. A. Vershinin
doaj
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
FEBS Open Bio, EarlyView.Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source