Results 101 to 110 of about 992,907 (313)

Impact of geothermal heating on the global ocean circulation

, 2001
The response of a global circulation model to a uniform geothermal heat flux of 50 mW m-2 through the sea floor is examined. If the geothermal heat input were transported upward purely by diffusion, the deep ocean would warm by 1.2°C. However, geothermal
Marotzke, J. ; https://orcid.org/, Marotzke, Jochem, Scott, J., Adcroft, A., Adcroft, Alistair, Scott, Jeffery R.   +5 more
core   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Concentrated heat storage for solar heating

Energy Procedia, 2010
AbstractThe Independent Solar System (ISS) project was initiated in 2008 in order to develop a solar thermal heating system capable of covering the full-year heat and hot water load of a single family house using high temperature thermal storage. A team of European solar thermal experts, research institutions and industrial partners developed the ...
openaire   +1 more source

Heating, ventilating, air-conditioning guide.

Vols. for 1922-37 issued as Guide of the American Society of Heating and Air-Conditioning Engineers under its earlier name.Vols. for 1922-59 published by the American Society of Heating and Air-Conditioning Engineers (called 1922-54, American Society of ...
American Society of Heating, Refrigerating and Air-Conditioning Engineers, American Society of Heating and Air-Conditioning Engineers. Guide., American Society of Heating and Air-Conditioning Engineers   +2 more
core  

Safety of localizing epilepsy monitoring intracranial electroencephalograph electrodes using MRI: radiofrequency-induced heating

, 2008
Purpose: To investigate heating during postimplantation localization of intracranial electroencephalograph (EEG) electrodes by MRI. Materials and Methods: A phantom patient with a realistic arrangement of electrodes was used to simulate tissue ...
Lemieux, L., Thornton, J.S., Carmichael, D.W., Rodionov, R., McEvoy, A., Thornton, R., Allen, P.J.   +6 more
core  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Enhancement of heat transfer in waste-heat heat exchangers [PDF]

, 1980
The Fluidfire shallow fluidized bed heat transfer facility was modified during this program to give increased air flow capacity and to allow testing with different distributor plates and with two-stage heat exchangers. Tests were conducted using this heat transfer facility to investigate the effect of reduced distributor plate pressure loss and amount ...
openaire   +2 more sources

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

[Men standing beside trucks at Heating and Ventilating Company]

, 1954
A few men standing beside trucks outside of the "Heating and Ventilating Company of Texas." All of the men are dressed in their work uniforms.
Douglass, Neal
core  

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source