Results 101 to 110 of about 2,511,519 (330)

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

FEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama, Nonoka Takayama, Rina Tanaka, Yuuki Arai, Yohko Yamaguchi, Yuko Nawata, Yutaro Azuma, Shusuke Tada   +7 more
wiley   +1 more source

Study and development of the process of production and using of peat-coke bricks at cast iron melting in cupola

Литьë и металлургия, 2003
In this article there are considered the problem of using of coke waste. There have been proposed to briquette coke waste with peat and use briquettes as the fuel for cupolas heating boilers and furnaces.
N. V. Svidunovich, N. V. Kislov, Ju. P. Bobrov, S. F. Lukashevich   +3 more
doaj  

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

FEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez, Everton G. Melo, Isadora C. B. Pavan, Percíllia V. S. Oliveira, Luiza B. C. T. Coimbra, Thaís L. S. Araujo   +5 more
wiley   +1 more source

Problems of production and using of briquetted metal discard

Литьë и металлургия, 2003
There is given the general information about development of metal discard recycling by means of briquetting, using bindings and deoxidizers.
N. A. Svidunovich, L. Z. Pisarenko, D. V. Kuis, Ju. P. Bobrov   +3 more
doaj  

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Experience of using of instruments MAXI for computer-aided control of the casting structure from annealed and high-test cast iron by magnetic method

Литьë и металлургия, 2002
The magnetic analyzer of production structure quality (MAXI-P) is created and applied in industry at ОАО "MZOO"The result of measuring is compared with the previously established usability ranges.
S. G. Sandomirski, L. Z. Pisarenko, S. F. Lukashevich   +2 more
doaj  

[Heat illness].

Nederlands tijdschrift voor geneeskunde, 2023
Thermoregulation keeps the normal body temperature of humans at approximately 37 °C. However, as a result of heat load - both endogenous and exogenous heat - it can occur that the body is unable to dissipate excess heat, leading to an increase in the core body temperature.
Hoek, Amber E., Dollee, Nathalie, Prins, Gerrie, Alsma, Jelmer   +3 more
openaire   +2 more sources

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming

FEBS Open Bio, EarlyView.
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar, Michael A. Ripperger, Grant M. Westlake, Kevin C. Ess   +3 more
wiley   +1 more source

Energy Supply for Heating the Slow Solar Wind Observed by Parker Solar Probe between 0.17 and 0.7 au

, 2020
Honghong Wu, Chuanyi Tu, Xin Wang, Jiansen He, Liping Yang   +4 more
openalex   +1 more source