Results 31 to 40 of about 423 (206)
Population‐weighted heating degree‐days for Canada [PDF]
Abstract The use of population‐weighted heating degree‐days provides a more realistic estimate of the potential fuel demand for residential heating on a regional, provincial or national basis than the use of unweighted, site‐specific heating degree‐day values.
openaire +1 more source
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Analysis of cooling and heating degree days in the United States from 2015 to 2024 [PDF]
A sizable portion of the electricity consumed in buildings is due to the thermal load associated with the location of these buildings. Specific environmental characteristics can be translated into factors that allow researchers to understand the ...
Barbosa Priscila M. +3 more
doaj +1 more source
Climate Change Effects on Heating and Cooling Demands of Buildings in Canada
Climate change is causing more frequent extreme weather events. The consequences of increasing global temperature on the operating cost of existing buildings, and the associated health, safety, and economic risks were investigated.
Samir E. Chidiac, Lan Yao, Paris Liu
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Climate Change and Vulnerabilities of the European Energy Balance
Energy consumption induces climate change but at the same time modifications in climate impact energy sector both in term of supply capacity and shifts in energy demands.
Giuliano Buceti
doaj +1 more source
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Energy consumption depends strongly on weather conditions. Thus, to formulate energy-related policy goals, it is crucial to monitor changes related to the heating degree days (HDD) and cooling degree days (CDD) – widely applied indicators of climate ...
Sylwia Pangsy-Kania +3 more
doaj +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source

