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Two Cases of Heavy Chain MGUS [PDF]
Case Reports in Oncological Medicine, 2016 Heavy chain diseases are rare variants of B-cell lymphomas that produce one of three classes of immunoglobulin heavy chains, without corresponding light chains. We describe two patients with asymptomatic heavy chain monoclonal gammopathy.
Jan Van Keer +4 more
doaj +6 more sources
Immunoglobulin heavy chain exclusion in the shark. [PDF]
PLoS Biology, 2008 The adaptive immune system depends on specific antigen receptors, immunoglobulins (Ig) in B lymphocytes and T cell receptors (TCR) in T lymphocytes.
Karolina Malecek +6 more
doaj +5 more sources
Antibodies, 2022 Serum anti-HLA-I IgG are present in non-alloimmunized males, cancer patients, and transplant recipients. Anti-HLA-I antibodies are also present in intravenous immunoglobulin (IVIg), prepared from the plasma of thousands of healthy donors.
Mepur H. Ravindranath +4 more
doaj +1 more source
Vaccines, 2022 Leukocyte cell-surface HLA-I molecules, involved in antigen presentation of peptides to CD8+ T-cells, consist of a heavy chain (HC) non-covalently linked to β2-microglobulin (β2m) (Face-1).
Mepur H. Ravindranath +5 more
doaj +1 more source
Spin chain on a metallic surface: Dissipation-induced order vs. Kondo entanglement [PDF]
Phys. Rev. B 106, L161103 (2022), 2022 We explore the physics of a spin-1/2 Heisenberg chain with Kondo interaction, $J_k$, to a two-dimensional electron gas. At weak $J_k$ the problem maps onto a Heisenberg chain locally coupled to a dissipative Ohmic bath. At the decoupled fixed point, the dissipation is a marginally relevant perturbation and drives long-range antiferromagnetic order ...
arxiv +1 more source
Maturation of the Human Immunoglobulin Heavy Chain Repertoire With Age
Frontiers in Immunology, 2020 B cells play a central role in adaptive immune processes, mainly through the production of antibodies. The maturation of the B cell system with age is poorly studied.
Marie Ghraichy +18 more
doaj +1 more source
The validation of artificial anti‐monkeypox antibodies by in silico and experimental approaches
Immunity, Inflammation and Disease, 2023 As a result of smallpox immunization programs that ended more than 40 years ago, a significant portion of the world's population is not immune. Moreover, due to the lack of anti‐monkeypox drugs and vaccines against monkeypox, the spread of this virus may
Sadeq Shabani +3 more
doaj +1 more source
Diagnostic Pathology, 2022 Background Mu heavy chain disease is a rare lymphoid neoplasm characterized by vacuolated bone marrow plasma cells and secretion of defective mu immunoglobulin heavy chains. The biological basis of mu heavy chain disease is poorly understood.
Vandana Baloda +9 more
doaj +1 more source
Heavy-Chain Deposition Disease [PDF]
New England Journal of Medicine, 1993 Comment inOminous consequences of immunoglobulin deposition. [N Engl J Med. 1993]
Aucouturier, Pierre +7 more
openaire +3 more sources